ID | 52900 |
JaLCDOI | |
FullText URL | |
Author |
Muro, Shinichiro
Nasu, Junichiro
Harada, Ryo
Matsubara, Minoru
Nakarai, Asuka
Uno, Masatoshi
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Abstract | A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle aspiration revealed Grade 3 small-cell type primary pancreatic neuroendocrine carcinoma. Consequently, the diagnosis of malignant insulinoma was made. Transarterial embolization (TAE) for hepatic metastases resulted in the reduction of tumor volume and prompt resolution of hypoglycemic attacks, whereas diazoxide and systemic chemotherapy had been ineffective for controlling blood glucose levels, and octreotide was unavailable due to the allergic effect. This case report highlights the potential usefulness of TAE for malignant insulinomas in the management of hypoglycemia.
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Keywords | malignant insulinoma
hypoglycemia
liver metastases
transarterial embolization
neuroendocrinetumor
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Amo Type | Case Report
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Publication Title |
Acta Medica Okayama
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Published Date | 2014-10
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Volume | volume68
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Issue | issue5
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Publisher | Okayama University Medical School
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Start Page | 307
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End Page | 311
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School
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File Version | publisher
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Refereed |
True
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PubMed ID | |
Web of Science KeyUT |