ID | 61302 |
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Author |
Okada, Masahiro
Department of Biomaterials, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
Hara, Emilio Satoshi
Department of Biomaterials, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Yabe, tsushi
Department of Biomaterials, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Okada, Kei
Department of Applied Chemistry and Biotechnology, Faculty of Engineering, Okayama University
Shibata, Yo
Department of Conservative Dentistry, Division of Biomaterials and Engineering, Showa University School of Dentistry
Torii , Yasuhiro
Department of Comprehensive Dentistry, Okayama University Hospital
Nakano, Takayoshi
Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University
Matsumoto, Takuya
Department of Biomaterials, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
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Abstract | A variety of polymer‐ and ceramic‐based soft‐tissue adhesives have been developed as alternatives to surgical sutures, yet several disadvantages regarding the mechanical properties, biocompatibility, and handling hinder their further application particularly when applied for immobilization of implantable devices. Here, it is reported that a biocompatible and tough metal, titanium (Ti), shows instant and remarkable adhesion properties after acid treatment, demonstrated by ex vivo shear adhesion tests with mouse dermal tissues. Importantly, in vivo experiments demonstrate that the acid‐treated Ti can easily and stably immobilize a device implanted in the mouse subcutaneous tissue. Collectively, the acid‐treated Ti is shown as a solid‐state instant adhesive material for biological soft tissues, which can have diverse applications including immobilization of body‐implantable devices.
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Keywords | acid treatment
adhesive
hydrophobic interaction
soft tissue
titanium
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Published Date | 2020-05-07
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Publication Title |
Advanced Materials Interfaces
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Volume | volume7
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Issue | issue9
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Publisher | Wiley
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Start Page | 1902089
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ISSN | 2196-7350
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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Copyright Holders | © 2020 The Authors.
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File Version | publisher
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DOI | |
Web of Science KeyUT | |
Related Url | isVersionOf https://doi.org/10.1002/admi.201902089
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License | https://creativecommons.org/licenses/by-nc-nd/4.0/
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Funder Name |
Japan Society for the Promotion of Science
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助成番号 | 18K09637
JP25220912
JP25293402
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