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ID 34235
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Author
Yamamoto, Masahiko
Zhu, Changjin
Yi, Lui
Rong, Zheng
Miura, Yoshie
Tanamoto, Ken-ichi
Shimizu, Sakayu
Baba, Naomichi
Abstract
Novel fatty acyl and phospholipid derivatives of pyrrole polyamide were synthesized. Their cytotoxicity against a cancer cell line of MT-4 cells and those infected by human immunodeficiency virus (HIV) was examined. Although no anti-HIV activity was found, their cytotoxicitty against the cancer cells was significantly enhanced by introducing a lipophilic group into the pyrrole polyamide.
Keywords
pyrrole polyamide
lipid
phospholipid
cancer cell
human immunodeficiency virus (HIV)-II
Note
Published with permission from the copyright holder.
This is published in Bioscience Biotechnology and Biochemistry, 2007 Vol.71 Issue.4 pp.1078-1082
Publisher URL: http://dx.doi.org/10.1271/bbb.60650
Direct access to Thomson Web of Science record
(C)2007 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
Published Date
2007-04
Publication Title
Bioscience, Biotechnology, and Biochemistry
Volume
volume71
Issue
issue4
Publisher
Japan Society for Bioscience, Biotechnology, and Agrochemistry
Publisher Alternative
日本農芸化学会
Start Page
1078
End Page
1082
ISSN
0916-8451
NCID
AA10824164
Content Type
Journal Article
language
英語
Copyright Holders
Japan Society for Bioscience, Biotechnology and Agrochemistry
File Version
publisher
Refereed
True
DOI
PubMed ID
Web of Science KeyUT
Submission Path
biochemistry/14