start-ver=1.4
cd-journal=joma
no-vol=36
cd-vols=
no-issue=11
article-no=
start-page=2875
end-page=2877
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210513
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The inhibitory effect of three degraded sesquiterpene lactones, iso-seco-tanapartholide, arteludooicinolide A and millifolide A isolated from Achillea millefolium L., on anti-human lung cancer cells was examined using MTT and reporter gene assays. Millifolide A has significant inhibitory effects on the proliferation of human lung cancer cells probably through inducing cell apoptosis. 
en-copyright=
kn-copyright=

en-aut-name=YuPan-Pan
en-aut-sei=Yu
en-aut-mei=Pan-Pan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=YuFeng
en-aut-sei=Yu
en-aut-mei=Feng
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=LiWen-Zhe
en-aut-sei=Li
en-aut-mei=Wen-Zhe
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=WangSi-Ming
en-aut-sei=Wang
en-aut-mei=Si-Ming
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=WangChuan
en-aut-sei=Wang
en-aut-mei=Chuan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=DongMei
en-aut-sei=Dong
en-aut-mei=Mei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=NiZhi-Yu
en-aut-sei=Ni
en-aut-mei=Zhi-Yu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=LiYong
en-aut-sei=Li
en-aut-mei=Yong
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=KiyotaHiromasa
en-aut-sei=Kiyota
en-aut-mei=Hiromasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

affil-num=1
en-affil=College of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification
kn-affil=

affil-num=2
en-affil=College of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification
kn-affil=

affil-num=3
en-affil=College of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification
kn-affil=

affil-num=4
en-affil=The Fourth Hospital of Hebei Medical University
kn-affil=

affil-num=5
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=6
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=7
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=8
en-affil=The Fourth Hospital of Hebei Medical University
kn-affil=

affil-num=9
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=
en-keyword=Achillea millefolium L
kn-keyword=Achillea millefolium L
en-keyword=millifolide A
kn-keyword=millifolide A
en-keyword=human lung cancer cells
kn-keyword=human lung cancer cells
en-keyword=antiproliferation
kn-keyword=antiproliferation
en-keyword=apoptosis 
kn-keyword=apoptosis 
END

start-ver=1.4
cd-journal=joma
no-vol=85
cd-vols=
no-issue=1
article-no=
start-page=134
end-page=142
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210121
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Synthesis of (12R,13S)-pyriculariol and (12R,13S)-dihydropyriculariol revealed that the rice blast fungus, Pyricularia oryzae, produces these phytotoxins as racemates
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Synthesis of assumed natural (12R,13S)-enantiomers of pyriculariol (1) and dihydropyriculariol (2), phytotoxins isolated from rice blast disease fungus, Pyricularia oryzae, was achieved using Wittig reaction or microwave-assisted Stille coupling reaction as the key step. The synthesis revealed that the natural 1 and 2 are racemates. Foliar application test on a rice leaf indicated that both the salicylaldehyde core and side chain were necessary for phytotoxic activity. The fungus is found to produce optically active phytotoxins when incubated with rotary shaker, but racemic ones when cultured using an aerated jar fermenter.
en-copyright=
kn-copyright=

en-aut-name=NagashimaYuta
en-aut-sei=Nagashima
en-aut-mei=Yuta
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SasakiAyaka
en-aut-sei=Sasaki
en-aut-mei=Ayaka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HiraokaRyoya
en-aut-sei=Hiraoka
en-aut-mei=Ryoya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=OnodaYuko
en-aut-sei=Onoda
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TanakaKoji
en-aut-sei=Tanaka
en-aut-mei=Koji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=WangZi-Yi
en-aut-sei=Wang
en-aut-mei=Zi-Yi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=KuwanaAtsuki
en-aut-sei=Kuwana
en-aut-mei=Atsuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=SatoYuki
en-aut-sei=Sato
en-aut-mei=Yuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=SuzukiYuji
en-aut-sei=Suzuki
en-aut-mei=Yuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=IzumiMinoru
en-aut-sei=Izumi
en-aut-mei=Minoru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=KuwaharaShigefumi
en-aut-sei=Kuwahara
en-aut-mei=Shigefumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

en-aut-name=NukinaManabu
en-aut-sei=Nukina
en-aut-mei=Manabu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=

en-aut-name=KiyotaHiromasa
en-aut-sei=Kiyota
en-aut-mei=Hiromasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=

affil-num=1
en-affil=Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University
kn-affil=

affil-num=2
en-affil=Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University
kn-affil=

affil-num=3
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=4
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=5
en-affil=Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University
kn-affil=

affil-num=6
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=7
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=8
en-affil=Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University
kn-affil=

affil-num=9
en-affil=Laboratory of Plant Nutrition and Function, Graduate School of Agricultural Science, Tohoku University
kn-affil=

affil-num=10
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=11
en-affil=Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University
kn-affil=

affil-num=12
en-affil=Professor Emeritus, Yamagata University
kn-affil=

affil-num=13
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=
en-keyword=Pyricularia oryzae
kn-keyword=Pyricularia oryzae
en-keyword=rice blast disease
kn-keyword=rice blast disease
en-keyword=structure revision
kn-keyword=structure revision
en-keyword=total synthesis 
kn-keyword=total synthesis 
END

start-ver=1.4
cd-journal=joma
no-vol=108
cd-vols=
no-issue=
article-no=
start-page=1
end-page=4
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus Species
kn-title=RƒŠ[ƒVƒ…ƒ}ƒjƒAŒด’ŽŠˆซ•จŽฟAncistrocladinium A‚ฦB‚ฬ‡ฌŒค‹†
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus sp., are described. Buchwald?Hartwig coupling reaction between the dihydroisoquinoline and the naphthyl triflate failed. The main framework of ancistrocladinium A was constructed by 1,2?addition of the amine to the naphthoquinone in the presence of celium trichloride as a catalyst. On the other hand, 1,4?addition of the amine to the naphthoquinone proceeded without catalyst to form the framework of B. These products will be valuable leads for antileishmanial agents.
en-copyright=
kn-copyright=

en-aut-name=KiyotaHiromasa
en-aut-sei=Kiyota
en-aut-mei=Hiromasa
kn-aut-name=ด“c—mณ
kn-aut-sei=ด“c
kn-aut-mei=—mณ
aut-affil-num=1
ORCID=

en-aut-name=SaitoAkihito
en-aut-sei=Saito
en-aut-mei=Akihito
kn-aut-name=โV“กบl
kn-aut-sei=โV“ก
kn-aut-mei=บl
aut-affil-num=2
ORCID=

en-aut-name=TakaiMomoko
en-aut-sei=Takai
en-aut-mei=Momoko
kn-aut-name=‚ˆไ“Žq
kn-aut-sei=‚ˆไ
kn-aut-mei=“Žq
aut-affil-num=3
ORCID=

en-aut-name=KuwaharaShigefumi
en-aut-sei=Kuwahara
en-aut-mei=Shigefumi
kn-aut-name=ŒKŒดd•ถ
kn-aut-sei=ŒKŒด
kn-aut-mei=d•ถ
aut-affil-num=4
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=‰ชŽR‘ๅŠw‘ๅŠw‰@@Šย‹ซถ–ฝ‰ศŠwŒค‹†‰ศ

affil-num=2
en-affil=Graduate School of Agricultural Science, Tohoku University
kn-affil=“Œ–k‘ๅŠw‘ๅŠw”_ŠwŒค‹†‰ศ

affil-num=3
en-affil=Graduate School of Agricultural Science, Tohoku University
kn-affil=“Œ–k‘ๅŠw‘ๅŠw”_ŠwŒค‹†‰ศ

affil-num=4
en-affil=Graduate School of Agricultural Science, Tohoku University
kn-affil=“Œ–k‘ๅŠw‘ๅŠw”_ŠwŒค‹†‰ศ
en-keyword=ancistrocladinium A and B
kn-keyword=ancistrocladinium A and B
en-keyword=synthetic studies
kn-keyword=synthetic studies
en-keyword=leishmania, Ancistrocladus
kn-keyword=leishmania, Ancistrocladus
en-keyword=isoquinoline
kn-keyword=isoquinoline
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=1
article-no=
start-page=8239
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=201708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= The design, synthesis and application of N-acetylneuraminic acid-derived compounds bearing anomeric sulfo functional groups are described. These novel compounds, which we refer to as sulfo-sialic acid analogues, include 2-decarboxy-2-deoxy-2-sulfo-N-acetylneuraminic acid and its 4-deoxy-3,4-dehydrogenated pseudoglycal. While 2-decarboxy-2-deoxy-2-sulfo-N-acetylneuraminic acid contains no further modifications of the 2-deoxy-pyranose ring, it is still a more potent inhibitor of avian-origin H5N1 neuraminidase (NA) and drug-resistant His275Tyr NA as compared to the oxocarbenium ion transition state analogue 2,3-dehydro-2-deoxy-N-acetylneuraminic acid. The sulfo-sialic acid analogues described in this report are also more potent inhibitors of influenza NA (up to 40-fold) and bacterial NA (up to 8.5-fold) relative to the corresponding anomeric phosphonic acids. These results confirm that this novel anomeric sulfo modification offers great potential to improve the potency of next-generation NA inhibitors including covalent inhibitors.
en-copyright=
kn-copyright=

en-aut-name=VavrickChristopher J.
en-aut-sei=Vavrick
en-aut-mei=Christopher J.
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=MutoChiaki
en-aut-sei=Muto
en-aut-mei=Chiaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HasunumaTomohisa
en-aut-sei=Hasunuma
en-aut-mei=Tomohisa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KimuraYoshinobu
en-aut-sei=Kimura
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=ArakiMichihiro
en-aut-sei=Araki
en-aut-mei=Michihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=WuYan
en-aut-sei=Wu
en-aut-mei=Yan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=GaoGeorge F.
en-aut-sei=Gao
en-aut-mei=George F.
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=OhruiHiroshi
en-aut-sei=Ohrui
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=IzumiMinoru
en-aut-sei=Izumi
en-aut-mei=Minoru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=KiyotaHiromasa
en-aut-sei=Kiyota
en-aut-mei=Hiromasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=2
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=3
en-affil=Graduate School of Science, Technology and Innovation, Kobe University
kn-affil=

affil-num=4
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=5
en-affil=Graduate School of Science, Technology and Innovation, Kobe University
kn-affil=

affil-num=6
en-affil=CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
kn-affil=

affil-num=7
en-affil=CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
kn-affil=

affil-num=8
en-affil=Yokohama College of Pharmacy
kn-affil=

affil-num=9
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=10
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=1
article-no=
start-page=8239
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=201708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= The design, synthesis and application of N-acetylneuraminic acid-derived compounds bearing anomeric sulfo functional groups are described. These novel compounds, which we refer to as sulfo-sialic acid analogues, include 2-decarboxy-2-deoxy-2-sulfo-N-acetylneuraminic acid and its 4-deoxy-3,4-dehydrogenated pseudoglycal. While 2-decarboxy-2-deoxy-2-sulfo-N-acetylneuraminic acid contains no further modifications of the 2-deoxy-pyranose ring, it is still a more potent inhibitor of avian-origin H5N1 neuraminidase (NA) and drug-resistant His275Tyr NA as compared to the oxocarbenium ion transition state analogue 2,3-dehydro-2-deoxy-N-acetylneuraminic acid. The sulfo-sialic acid analogues described in this report are also more potent inhibitors of influenza NA (up to 40-fold) and bacterial NA (up to 8.5-fold) relative to the corresponding anomeric phosphonic acids. These results confirm that this novel anomeric sulfo modification offers great potential to improve the potency of next-generation NA inhibitors including covalent inhibitors.
en-copyright=
kn-copyright=

en-aut-name=VavrickaChristopher J.
en-aut-sei=Vavricka
en-aut-mei=Christopher J.
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=MutoChiaki
en-aut-sei=Muto
en-aut-mei=Chiaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HasunumaTomohisa
en-aut-sei=Hasunuma
en-aut-mei=Tomohisa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=KimuraYoshinobu
en-aut-sei=Kimura
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=ArakiMichihiro
en-aut-sei=Araki
en-aut-mei=Michihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=WuYan
en-aut-sei=Wu
en-aut-mei=Yan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=GaoGeorge F.
en-aut-sei=Gao
en-aut-mei=George F.
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=OhruiHiroshi
en-aut-sei=Ohrui
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=IzumiMinoru
en-aut-sei=Izumi
en-aut-mei=Minoru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=KiyotaHiromasa
en-aut-sei=Kiyota
en-aut-mei=Hiromasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=2
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=3
en-affil=Graduate School of Science, Technology and Innovation, Kobe University
kn-affil=

affil-num=4
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=5
en-affil=Graduate School of Science, Technology and Innovation, Kobe University
kn-affil=

affil-num=6
en-affil=CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
kn-affil=

affil-num=7
en-affil=CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
kn-affil=

affil-num=8
en-affil=Yokohama College of Pharmacy
kn-affil=

affil-num=9
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=

affil-num=10
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=
en-keyword=Antiviral agents
kn-keyword=Antiviral agents
en-keyword=Drug discovery and development
kn-keyword=Drug discovery and development
en-keyword=Glycosides
kn-keyword=Glycosides
END

start-ver=1.4
cd-journal=joma
no-vol=106
cd-vols=
no-issue=
article-no=
start-page=33
end-page=38
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Enzyme-catalyzed synthesis and odor evaluation of both enantiomers of perfume compounds
kn-title=y‘fG”}”ฝ‰ž‚๐Œฎ‚ฦ‚ท‚้Œ๕ŠwŠˆซ‚ศ‹C•จŽฟ—ผ‹พ‘œ‘ฬ‚ฬ‡ฌ‚ฦ‹C•]‰ฟ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Synthesis of both enantiomers of some perfume compounds, and their difference in aroma
characteristics are described. Enantiomeric pairs of methyl jasmonate and its 4,5-didehydro congener, principal components of jasmin absolute, were prepared from the corresponding commercially available racemates using lipase-catalyzed optical resolution. The E-value for the reaction is as high as 370. The nature-identical isomers produced superior aroma activity relative to unnatural ones. Racemic lavandulol from a commercial source, was also resolved using several enzymatic transesterifications followed by hydrolysis with PPL. Odor evaluation revealed that the nature-identical isomer should play a key role in lavender oil. Cis-ƒฟ-irone and cis-ƒม-irone, used as important violet components for perfumery, were synthesized in optically active forms through fractional crystallization of the diastereomeric salts with ƒฟ-phenethylamine. The nature-identical irones also had better floral characteristics like ionone.
en-copyright=
kn-copyright=

en-aut-name=KiyotaHiromasa
en-aut-sei=Kiyota
en-aut-mei=Hiromasa
kn-aut-name=ด“c—mณ
kn-aut-sei=ด“c
kn-aut-mei=—mณ
aut-affil-num=1
ORCID=

affil-num=1
en-affil=Graduate School of Environmental and Life Science, Okayama University
kn-affil=‰ชŽR‘ๅŠw‘ๅŠw‰@Šย‹ซถ–ฝ‰ศŠwŒค‹†‰ศ
en-keyword=flavor and fragrance
kn-keyword=flavor and fragrance
en-keyword=enantiomers
kn-keyword=enantiomers
en-keyword=synthesis
kn-keyword=synthesis
en-keyword=methyl jasmonate
kn-keyword=methyl jasmonate
en-keyword=lavandulol
kn-keyword=lavandulol
en-keyword=irone
kn-keyword=irone
END

start-ver=1.4
cd-journal=joma
no-vol=98
cd-vols=
no-issue=5
article-no=
start-page=691
end-page=698
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2015
dt-pub=20150526
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=New Limonoids from the Seeds of Xylocarpus granatum
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Three novel limonoids, 2,3-dideacetylxyloccensin S (1), 30-deacetylxyloccensin W (2), and 7-hydroxy-21ƒภ-methoxy-3-oxo-24,25,26,27-tetranortirucalla-1,14-diene-23(21)-lactone (3), were isolated from the seeds of the Chinese mangrove, Xylocarpus granatum. The structures were elucidated on the basis of 1D- and 2D-NMR (including 1H- and 13C-NMR, DEPT, 1H,1H-COSY, HSQC, HMBC, and NOESY) data and confirmed by HR-MS.
en-copyright=
kn-copyright=

en-aut-name=WuYi-Bing
en-aut-sei=Wu
en-aut-mei=Yi-Bing
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=LiuDan
en-aut-sei=Liu
en-aut-mei=Dan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=LiuPei-Yu
en-aut-sei=Liu
en-aut-mei=Pei-Yu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YangXue-Mei
en-aut-sei=Yang
en-aut-mei=Xue-Mei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=LiaoMan
en-aut-sei=Liao
en-aut-mei=Man
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=LuNan-Nan
en-aut-sei=Lu
en-aut-mei=Nan-Nan
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=SauriolFran?oise
en-aut-sei=Sauriol
en-aut-mei=Fran?oise
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=GuYu-Cheng
en-aut-sei=Gu
en-aut-mei=Yu-Cheng
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=ShiQing-Wen
en-aut-sei=Shi
en-aut-mei=Qing-Wen
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=KiyotaHiromasa
en-aut-sei=Kiyota
en-aut-mei=Hiromasa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=DongMei
en-aut-sei=Dong
en-aut-mei=Mei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University

affil-num=2
en-affil=
kn-affil=School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University

affil-num=3
en-affil=
kn-affil=School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University

affil-num=4
en-affil=
kn-affil=School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University

affil-num=5
en-affil=
kn-affil=School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University

affil-num=6
en-affil=
kn-affil=School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University

affil-num=7
en-affil=
kn-affil=Department of Chemistry, Queen?s University

affil-num=8
en-affil=
kn-affil=Syngenta Jealott?s Hill International Research Centre

affil-num=9
en-affil=
kn-affil=School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University

affil-num=10
en-affil=
kn-affil=Graduate School of Environmental and Life Science, Okayama University

affil-num=11
en-affil=
kn-affil=Hebei Key Laboratory of Forensic Medicine, Hebei Medical University
END