FullText URL | fulltext20211006-2a.pdf |
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Author | Kamada, Yasuhiko| Kusumoto, Rie| Kashino, Chiaki| Kubo, Kotaro| Mitsui, Takashi| Masuyama, Hisashi| |
Keywords | double cross plasty genital chronic graft-versus-host disease hematocolpos hematopoietic stem cell transplantation vaginal reconstruction |
Note | This is the peer reviewed version of the following article: [Kamada, Y., Kusumoto, R., Kashino, C., Kubo, K., Mitsui, T., & Masuyama, H. (2021). Surgically treated genital chronic graft‐versus‐host disease in women: A report of three cases. Journal of Obstetrics and Gynaecology Research.], which has been published in final form at [https://doi.org/10.1111/jog.15005]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-ArchivedVersions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wileyor by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked toWiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof bythird parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
Published Date | 2021-09-05 |
Publication Title | Journal of Obstetrics and Gynaecology Research |
Volume | volume47 |
Issue | issue11 |
Publisher | Wiley |
Start Page | 4122 |
End Page | 4126 |
ISSN | 1341-8076 |
NCID | AA11082002 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Japan Society of Obstetrics and Gynecology |
File Version | author |
PubMed ID | 34482585 |
DOI | 10.1111/jog.15005 |
Web of Science KeyUT | 000697443000001 |
Related Url | isVersionOf https://doi.org/10.1111/jog.15005 |
JaLCDOI | 10.18926/AMO/58269 |
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FullText URL | 74_2_115.pdf |
Author | Kotani, Sayoko| Kamada, Yasuhiko| Shimizu, Keiko| Sakamoto, Ai| Nakatsuka, Mikiya| Hiramatsu, Yuji| Masuyama, Hisashi| |
Abstract | Thrombosis in decidual vessels is one of the mechanisms of pregnancy loss. However, few studies have assessed the relation between platelet activation, which is known to cause of thrombosis, and recurrent pregnancy loss (RPL). We investigated platelet activation in women with RPL compared to controls by measuring plasma levels of platelet factor 4 (PF4) and β-thromboglobulin (βTG), and assessed correlations between PF4/βTG and coagulative risk factors associated with RPL. The study group included 135 women who had experienced two or more consecutive pregnancy losses. The control group included 28 age-matched healthy women who had never experienced pregnancy loss. PF4 and βTG plasma levels were significantly higher in the women with RPL than controls (PF4: 14.0 [8.0-20.0] vs. 9.0 [6.0-12.0] ng/ml, p=0.043; βTG: 42.0 [24.3-59.8] vs. 31.5 [26.6-36.4] ng/ml, p=0.002). There was a significant association between βTG and anti-phosphatidylethanolamine antibody immunoglobulin M (aPE IgM) (p=0.048). Among the women with RPL, 18 of those who were positive for PF4 (45%) and 18 of those who were positive for βTG (37%) were negative for all known coagulative risk factors associated with RPL. Measurements of PF4 and βTG may be important because they help identify women who are at risk of RPL. |
Keywords | recurrent pregnancy loss platelet factor 4 β-thromboglobulin platelet activation |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-04 |
Volume | volume74 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 115 |
End Page | 122 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32341585 |
Web of Science KeyUT | 000528278500004 |
NAID | 120006839448 |
Author | Kamada, Yasuhiko| Hiramatsu, Yuji| |
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Published Date | 2008-01-04 |
Publication Title | 岡山医学会雑誌 |
Volume | volume119 |
Issue | issue3 |
Content Type | Journal Article |
Author | 鎌田 泰彦| |
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Published Date | 2001-03-25 |
Publication Title | |
Content Type | Thesis or Dissertation |