FullText URL | fulltext20220509-1.pdf Supporting_Information20220509-1.pdf |
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Author | Ohtsuka, Satomi| Okumura, Taisei| Τabuchi, Yuna| Miyagawa, Tomoyuki| Kanayama, Naoki| Magari, Masaki| Hatano, Naoya| Sakagami, Hiroyuki| Suizu, Futoshi| Ishikawa, Teruhiko| Tokumitsu, Hiroshi| |
Note | This document is the Accepted Manuscript version of a Published Work that appeared in final form in Biochemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.biochem.1c00796| |
Published Date | 2022-03-11 |
Publication Title | Biochemistry |
Volume | volume61 |
Issue | issue7 |
Publisher | American Chemical Society (ACS) |
Start Page | 545 |
End Page | 553 |
ISSN | 0006-2960 |
NCID | AA00564599 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | Copyright © 2022 American Chemical Society |
File Version | author |
DOI | 10.1021/acs.biochem.1c00796 |
Web of Science KeyUT | 000783678600007 |
Related Url | isVersionOf https://doi.org/10.1021/acs.biochem.1c00796 |
JaLCDOI | 10.18926/46955 |
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FullText URL | mfe_38_1-2_091_096.pdf |
Author | Kanayama, Naoki| Yamakoshi, Kimi| Kiyomi, Masaaki| Magari, Masaki| Ohmori, Hitoshi| |
Abstract | Generally, IgM antibodies (Abs) produced in a primary immune response show lower affinity for an inducing antigen (Ag) compared with the corresponding IgG Abs that are major switched isotypes formed in the secondary response. An IgM molecule is a pentamer with 10 Ag-binding sites that will contribute to an increase of avidity for an Ag. To estimate the contribution of the pentameric structure to the avidity of an IgM Ab, we generated IgM and IgG1 monoclonal Abs (mAbs) with identical V regions that are specific for 4-hydroxy-3-nitrophenylacetyl (NP) by in vitro class switching of B cells followed by the cell fusion with a mouse myeloma cell line. Compared with an anti-NP IgG1 mAb, the corresponding IgM mAb showed much higher avidity for NP-conjugated bovine serum albumin, which was drastically reduced after being dissociated into monomers. |
Publication Title | Memoirs of the Faculty of Engineering, Okayama University |
Published Date | 2004-03 |
Volume | volume38 |
Issue | issue1-2 |
Start Page | 91 |
End Page | 96 |
ISSN | 0475-0071 |
language | English |
File Version | publisher |
NAID | 80017001822 |
FullText URL | fulltext.pdf |
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Author | Yamamoto, Maho| Kondo, Rina| Hozumi, Haruka| Doi, Seita| Denda, Miwako| Magari, Masaki| Kanayama, Naoki| Hatano, Naoya| Morishita, Ryo| Tokumitsu, Hiroshi| |
Keywords | S100 protein HMG20A protein-protein interaction Ca2+-signal transduction genome-wide screening |
Published Date | 2021-03-30 |
Publication Title | Biomolecules |
Volume | volume11 |
Issue | issue4 |
Publisher | MDPI |
Start Page | 510 |
ISSN | 2218-273X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | publisher |
PubMed ID | 33808200 |
NAID | 120007037385 |
DOI | 10.3390/biom11040510 |
Web of Science KeyUT | 000642769800001 |
Related Url | isVersionOf https://doi.org/10.3390/biom11040510 |
FullText URL | fulltext20220106-5.pdf |
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Author | Fukumoto, Yusei| Harada, Yuhei| Ohtsuka, Satomi| Kanayama, Naoki| Magari, Masaki| Hatano, Naoya| Sakagami, Hiroyuki| Tokumitsu, Hiroshi| |
Keywords | CaMKK oligomerization Ca2+-signaling phosphorylation CaM kinase cascade |
Note | © 2021 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.bbrc.2021.11.105] .| |
Published Date | 2022-1 |
Publication Title | Biochemical and Biophysical Research Communications |
Volume | volume587 |
Publisher | Elsevier BV |
Start Page | 160 |
End Page | 165 |
ISSN | 0006-291X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Elsevier Inc. |
File Version | author |
PubMed ID | 34875535 |
DOI | 10.1016/j.bbrc.2021.11.105 |
Web of Science KeyUT | 000729413200005 |
Related Url | isVersionOf https://doi.org/10.1016/j.bbrc.2021.11.105 |
FullText URL | BBRC_525_1_251_257.pdf |
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Author | Takabatake, Shota| Fukumoto, Yusei| Ohtsuka, Satomi| Kanayama, Naoki| Magari, Masaki| Sakagami, Hiroyuki| Hatano, Naoya| Tokumitsu, Hiroshi| |
Keywords | CaMKKβ Phosphorylation Dephosphorylation PP1 PP2A Okadaic acid |
Note | This fulltext is available in Feb. 2021.| |
Published Date | 2020-04-23 |
Publication Title | Biochemical and Biophysical Research Communications |
Volume | volume525 |
Issue | issue1 |
Publisher | Academic Press |
Start Page | 251 |
End Page | 257 |
ISSN | 0006-291X |
NCID | AA00564395 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 32085894 |
DOI | 10.1016/j.bbrc.2020.02.056 |
Web of Science KeyUT | 000526797700039 |
Related Url | isVersionOf https://doi.org/10.1016/j.bbrc.2020.02.056 |
FullText URL | BBA_1863_4_672.pdf |
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Author | Takabatake, Shota| Ohtsuka, Satomi| Sugawara, Takeyuki| Hatano, Naoya| Kanayama, Naoki| Magari, Masaki| Sakagami, Hiroyuki| Tokumitsu, Hiroshi| |
Keywords | CaMKK Calmodulin Intracellular Ca(2+) PKA Phosphorylation Signal transduction |
Published Date | 2019-01-17 |
Publication Title | Biochimica et Biophysica Acta (BBA) - General Subjects |
Volume | volume1863 |
Issue | issue4 |
Publisher | Elsevier Science |
Start Page | 672 |
End Page | 680 |
ISSN | 0304-4165 |
NCID | AA00564679 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 30660766 |
DOI | 10.1016/j.bbagen.2018.12.012 |
Web of Science KeyUT | 000460853200003 |
Related Url | isVersionOf https://doi.org/10.1016/j.bbagen.2018.12.012 |
FullText URL | BBRC_485_2_261.pdf |
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Author | Kawaguchi, Yuka| Nariki, Hiroaki| Kawamoto, Naoko| Kanehiro, Yuichi| Miyazaki, Satoshi| Suzuki, Mari| Magari, Masaki| Tokumitsu, Hiroshi| Kanayama, Naoki| |
Keywords | AID DT40 Gene conversion Ig SRSF1 Somatic hypermutation |
Published Date | 2017-04 |
Publication Title | Biochemical and Biophysical Research Communications |
Volume | volume485 |
Issue | issue2 |
Publisher | Elsevier |
Start Page | 261 |
End Page | 266 |
ISSN | 0006-291X |
NCID | AA00564395 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
File Version | author |
PubMed ID | 28235482 |
DOI | 10.1016/j.bbrc.2017.02.097 |
Web of Science KeyUT | 000396798300007 |
Related Url | isVersionOf https://doi.org/10.1016/j.bbrc.2017.02.097 |
FullText URL | fulltext20220602-1.pdf |
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Author | Kaneshige, Riku| Ohtsuka, Satomi| Harada, Yuhei| Kawamata, Issei| Magari, Masaki| Kanayama, Naoki| Hatano, Naoya| Sakagami, Hiroyuki| Tokumitsu, Hiroshi| |
Keywords | AMP-activated protein kinase Arg/Pro-rich insert domain (RP-domain) calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase kinase substrate recognition |
Note | This is the peer reviewed version of the following article: [Kaneshige, R., Ohtsuka, S., Harada, Y., Kawamata, I., Magari, M., Kanayama, N., Hatano, N., Sakagami, H. and Tokumitsu, H. (2022), Substrate recognition by Arg/Pro-rich insert domain in calcium/calmodulin-dependent protein kinase kinase for target protein kinases. FEBS J, 289: 5971-5984. https://doi.org/10.1111/febs.16467], which has been published in final form at [https://doi.org/10.1111/febs.16467]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext will be available in May 2023.| |
Published Date | 2022-05-17 |
Publication Title | The FEBS Journal |
Volume | volume289 |
Issue | issue19 |
Publisher | Wiley |
Start Page | 5971 |
End Page | 5984 |
ISSN | 1742-464X |
NCID | AA11998513 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 Federation of European Biochemical Societies. |
File Version | author |
PubMed ID | 35490408 |
DOI | 10.1111/febs.16467 |
Web of Science KeyUT | 000796673600001 |
Related Url | isVersionOf https://doi.org/10.1111/febs.16467 |