start-ver=1.4
cd-journal=joma
no-vol=10
cd-vols=
no-issue=1
article-no=
start-page=4387
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200309
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Three-dimensional observation and analysis of remineralization in dentinal caries lesions
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The remineralization mechanism in dental caries lesions is not completely understood. This study reports on ultrastructural and chemical changes observed within arrested caries lesions. Carious human teeth were observed using scanning electron microscopy (SEM) and focused-ion-beam (FIB)-SEM. The crystals detected in the caries lesions were characterized by transmission electron microscopy (TEM), along with chemical element mapping using energy-dispersive spectroscopy (EDS)-STEM. FIB-SEM 3D reconstructions revealed a severely damaged dentin surface abundantly covered by bacteria. Although the dentin tubules were clogged up to a depth of 100 mu m, bacterial invasion into dentin tubules was not observed. TEM crystal analysis and EDS-STEM revealed the presence of Ca and P, as well as of Mg within the HAp crystals deposited inside the dentin tubules. It was concluded that extensive remineralization with deposition of Mg-HAp crystals had occurred in dentin tubules of caries-arrested dentin. Understanding the natural remineralization process is thought to be helpful for developing clinical biomimetic remineralization protocols.
en-copyright=
kn-copyright=

en-aut-name=YoshiharaKumiko
en-aut-sei=Yoshihara
en-aut-mei=Kumiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=NagaokaNoriyuki
en-aut-sei=Nagaoka
en-aut-mei=Noriyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=NakamuraAkiko
en-aut-sei=Nakamura
en-aut-mei=Akiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=HaraToru
en-aut-sei=Hara
en-aut-mei=Toru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=YoshidaYasuhiro
en-aut-sei=Yoshida
en-aut-mei=Yasuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=Van MeerbeekMeerbeek, Bart
en-aut-sei=Van Meerbeek
en-aut-mei=Meerbeek, Bart
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

affil-num=1
en-affil=Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Pathology & Experimental Medicine
kn-affil=

affil-num=2
en-affil=Okayama University Dental School, Advanced Research Center for Oral and Craniofacial Sciences
kn-affil=

affil-num=3
en-affil=National Institute for Materials Science
kn-affil=

affil-num=4
en-affil=National Institute for Materials Science
kn-affil=

affil-num=5
en-affil=Okayama University, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Biomaterials Laboratory
kn-affil=

affil-num=6
en-affil=Hokkaido University, Faculty of Dental Medicine, Department of Biomaterials and Bioengineering
kn-affil=

affil-num=7
en-affil=KU Leuven (University of Leuven), Department of Oral Health Research, BIOMAT & UZ Leuven (University Hospitals Leuven)
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=7
cd-vols=
no-issue=1
article-no=
start-page=90
end-page=100
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190211
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Accelerated induction of in vitro apatite formation by parallel alignment of hydrothermally oxidized titanium substrates separated by sub-millimeter gaps
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= Although autoclaving is a common sterilization method for biomedical devices, the ability to induce deposition of apatite particles on hydrothermally treated titanium is still not fully realized. This is because the induction ability is too weak to be evaluated via in vitro apatite formation in Kokubo's simulated body fluid (SBF) by the conventional immersion method, i.e. using samples with open and smooth surface. This study reports on the surface structure of hydrothermally treated titanium and the ability to induce deposition of apatite particles on the surface of parallel confined spaces separated by sub-millimeter gaps in Kokubo's SBF. Thin-film X-ray diffraction and analyses using Fourier transform infra-red (FT-IR) spectroscopy and Raman spectroscopy revealed that a nano-crystalline anatase-type titanium oxide layer was formed on titanium substrates after hydrothermal treatment at 150 degrees C for 2 h. When growth of the titanium oxide layer was moderately suppressed, the hydrothermally treated titanium surface exhibited a characteristic interference color, silver or gold, which does not impair the esthetic appearance of the titanium-based implant. The ability to induce deposition of apatite particles on hydrothermally treated titanium was remarkably amplified by parallel alignment of substrates separated by sub-millimeter gaps.
en-copyright=
kn-copyright=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=OkamotoKeigo
en-aut-sei=Okamoto
en-aut-mei=Keigo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=2
en-affil=Biomaterials Laboratory, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=3
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
en-keyword=Titanium substrate
kn-keyword=Titanium substrate
en-keyword=apatite deposition
kn-keyword=apatite deposition
en-keyword=simulated body fluid
kn-keyword=simulated body fluid
en-keyword=parallel alignment
kn-keyword=parallel alignment
en-keyword=titania layer
kn-keyword=titania layer
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20191202
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Comparative study of in vitro apatite-forming abilities of highly ordered rutile nanorod arrays fabricated on cpTi and Ti6Al4V alloys
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= The surfaces of commercially available pure titanium (cpTi) and Ti6Al4V alloy specimens were modified to form highly ordered rutile nanorod arrays by chemical treatment and subsequent aging treatment. The densities of the rutile rods were (1.04 +/- 0.06) x10(3) and (0.70 +/- 0.10) x10(3) mu m(-2) for the cpTi and Ti6Al4V alloy specimens, respectively. Both the rutile nanorod arrays on the cpTi and Ti6Al4V alloy specimens deposited apatite particles when soaked in simulated body fluid (SBF) for one day. After soaking for various other periods, scanning electron microscopy images and thin-film X-ray diffraction patterns of these specimens showed that the cpTi specimens exhibited a superior rate of apatite nucleation and favored the formation of numerous apatite particles with larger diameter. This superior apatite-forming ability of the cpTi specimens can be attributed to the dense, thick titania layers with higher rutile nanorod density on their surfaces.
en-copyright=
kn-copyright=

en-aut-name=LiuXingzhu
en-aut-sei=Liu
en-aut-mei=Xingzhu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

affil-num=1
en-affil=Biomaterials Laboratory, Graduate School of Natural Science and Technology, Okayama University
kn-affil=

affil-num=2
en-affil=Biomaterials Laboratory, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=

affil-num=3
en-affil=Biomaterials Laboratory, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
en-keyword=Rutile
kn-keyword=Rutile
en-keyword=nanorod arrays
kn-keyword=nanorod arrays
en-keyword=apatite
kn-keyword=apatite
en-keyword=rod density
kn-keyword=rod density
END

start-ver=1.4
cd-journal=joma
no-vol=36
cd-vols=
no-issue=2
article-no=
start-page=67
end-page=72
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=200203
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Preparation of alginic acid layers on solid substrates for biomedical applications
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Alginic acid was immobilized on ƒΑ-aminopropyltriethoxysilane-coated glass as a model substrate since an alginic acid layer was known to prevent cell adhesion. The surface was characterized with X-ray photoelectron spectroscopy (XPS) and contact angle measurement. The coated substrates adsorbed practically no calcium phosphates on their surfaces when soaked in a simulated body fluid (SBF) of Kolrubo recipe. Since calcium ions are one of the factors for blood clotting, the present alginic acid coating is one of the candidates to improve blood compatibility of clinical materials.
en-copyright=
kn-copyright=

en-aut-name=YoshiokaTomohiko
en-aut-sei=Yoshioka
en-aut-mei=Tomohiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TsuruKanji
en-aut-sei=Tsuru
en-aut-mei=Kanji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=2
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=3
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=4
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
END

start-ver=1.4
cd-journal=joma
no-vol=36
cd-vols=
no-issue=1
article-no=
start-page=117
end-page=121
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=200112
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Improvement of Biocompatibility of Silicone Elastomer by Surface Modification
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=ƒΑ-Methacryloxypropyltrimethoxysilane (ƒΑ-MPS) was grafted to silicone due to emulsion polymerization to induce Si-OH groups, in order to provide silicone with bioactivity spontaneous deposition of apatite in body fluid and to improve cytocompatibility. Apatite deposited on the grafted silicone within 7 days of soaking in 1.5 times as concentrated as the Kokubo solution. Osteoblastic cells (MC3T3-E1) were cultured on the specimens up to 7 days. After 5 days of culture, the number of MC3T3-E1 cells on the grafted specimen was much greater than that on the original specimen. These results indicated that the biocompatibility of silicone elastomer was improved by the grafting ƒΑ-MPS.
en-copyright=
kn-copyright=

en-aut-name=ShirosakiYuki
en-aut-sei=Shirosaki
en-aut-mei=Yuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=TsuruKanji
en-aut-sei=Tsuru
en-aut-mei=Kanji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=TakashimaSeisuke
en-aut-sei=Takashima
en-aut-mei=Seisuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=2
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=3
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=4
en-affil=
kn-affil=Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University

affil-num=5
en-affil=
kn-affil=Co-operative Research Center, Okayama University
END

start-ver=1.4
cd-journal=joma
no-vol=33
cd-vols=
no-issue=2
article-no=
start-page=79
end-page=84
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990427
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Apatite Formation on Electrochemically Treated Titanium
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A titanium oxide gel was electrochemically prepared on Ti with a cell consisting of Ti as the working electrode, Pt as the counter one, AgCl as the reference one, and an aqueous solution of 0.1 mol/L Ca(NO(3))(2) as the electrolyte solution. The Ti electrode was kept at 9.5V for 1 hr for oxidation and subsequently kept at-3.0V for 10 min (Ca9.5-3.0):calcium ions were expected to be adsorbed at the latter treatment. Other Ti specimen was kept at -3.0V for 10 min (Ca-3.0). Both specimens were found so bioactive as to deposit apatite in 12 hr (Ca9.5-3.0) and in 1 day (Ca-3.0) when soaked in a simulated body fluid (Kokubo solution). Calcium carbonate detected on the surface of Ca9.5-3.0 caused no harmful effects on spontaneous deposition of apatite in the fluid.
en-copyright=
kn-copyright=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=”φβ–Ύ‹`
kn-aut-sei=”φβ
kn-aut-mei=–Ύ‹`
aut-affil-num=1
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=‘μ‘
kn-aut-sei=‘μ
kn-aut-mei=‘
aut-affil-num=2
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=KoyanoKeiko
kn-aut-sei=Koyano
kn-aut-mei=Keiko
aut-affil-num=3
ORCID=

en-aut-name=TsuruKanji
en-aut-sei=Tsuru
en-aut-mei=Kanji
kn-aut-name=“s—―Š°Ž‘
kn-aut-sei=“s—―
kn-aut-mei=Š°Ž‘
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=2
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=3
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=4
en-affil=
kn-affil=Graduate School of Natural Science, Okayama University
END

start-ver=1.4
cd-journal=joma
no-vol=31
cd-vols=
no-issue=2
article-no=
start-page=45
end-page=51
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970328
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Bioactive Calcium Borosilicate Glasses for Enameling Titanium
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The thermal expansion coefficient of some bioactive glasses in the system CaO-SiO(2)-B(2)O(3) were adjusted to be similar to that of titanium by controlling the composition. A glass of composition 45CaO₯30SiO(2)₯25B(2)O(3) was selected among those as the enameling glass. A slurry was prepared by mixing the glass powder and ethanal to be developed on titanium and heated at 740Ž for 30 min. Thus treated specimen was soaked in a simulated body fluid (Kokubo solutiion). FT-IR reflection and thin film X-ray diffraction analyses indicated apatite formation on the glass coating layer within 12 h of soaking in the fluid. Thus titanium could be provided with bioactivity due to the enameling.
en-copyright=
kn-copyright=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=”φβ–Ύ‹`
kn-aut-sei=”φβ
kn-aut-mei=–Ύ‹`
aut-affil-num=1
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=KobayashiKeizo
kn-aut-sei=Kobayashi
kn-aut-mei=Keizo
aut-affil-num=2
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=‘μ‘
kn-aut-sei=‘μ
kn-aut-mei=‘
aut-affil-num=3
ORCID=

en-aut-name=OhtsukiChikara
en-aut-sei=Ohtsuki
en-aut-mei=Chikara
kn-aut-name=‘ε’ΞŽεΕ
kn-aut-sei=‘ε’Ξ
kn-aut-mei=ŽεΕ
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioengineering Science

affil-num=2
en-affil=
kn-affil=Department of Bioengineering Science

affil-num=3
en-affil=
kn-affil=Department of Bioengineering Science

affil-num=4
en-affil=
kn-affil=Department of Bioengineering Science
END

start-ver=1.4
cd-journal=joma
no-vol=31
cd-vols=
no-issue=2
article-no=
start-page=39
end-page=44
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1997
dt-pub=19970328
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Bioactivity of Nb(V) and Ta(V)-Doped Calcium Silicate Glasses
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Nb(2)O(5)-and Ta(2)O(5)-doped calcium si1icate glasses were soaked for various periods in a simulated body fluid(Kokubo solution) up to 30 days. Apatite formation ability of the surface of these glasses were investigated with thin-film X-ray diffraction and FT-IR reflection spectroscopy. The effects of these additive oxides on the bioactivity of CaO₯SiO(2) based glass were discussed. A small amount of Nb(2)O(5) and Ta(2)O(5) suppressed the rate of silica hydrogel layer formation and the apatite formation on the surface of the glasses. The rate of the apatite nucleation on the surface of Nb(2)O(5)-doped calcium silicate glass was slower than that on the surface of Ta(2)O(5)-doped calcium silicate glass. It was concluded that the decrease in the apatite forming ability of calcium silicate glasses by these additive oxides is attributed to the suppression of formation of silica hydrogel layer which plays an important role in apatite nucleation.
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=ImayoshiNaoki
kn-aut-sei=Imayoshi
kn-aut-mei=Naoki
aut-affil-num=1
ORCID=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=‘μ‘
kn-aut-sei=‘μ
kn-aut-mei=‘
aut-affil-num=2
ORCID=

en-aut-name=OhtsukiChikara
en-aut-sei=Ohtsuki
en-aut-mei=Chikara
kn-aut-name=‘ε’ΞŽεΕ
kn-aut-sei=‘ε’Ξ
kn-aut-mei=ŽεΕ
aut-affil-num=3
ORCID=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=”φβ–Ύ‹`
kn-aut-sei=”φβ
kn-aut-mei=–Ύ‹`
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=2
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=3
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=4
en-affil=
kn-affil=Department of Bioscience and Biotechnology
END

start-ver=1.4
cd-journal=joma
no-vol=34
cd-vols=
no-issue=1-2
article-no=
start-page=39
end-page=43
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2000
dt-pub=20000327
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Cytocompatibility of Silicone Elastomer Treated with Hydrogenperoxide Containing Tantalum Chloride
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Silicone elastomer was chemically treated at 60Ž for 7 days with 30 wt% H(2)O(2) solutions with or without TaCl(5) and soaked for various periods in a simulated body
fluid(Kokubo solution) up to 21 days. Apatite formation ability of the surface of the silicone elastomer specimens was investigated with thin-film X-ray diffraction and FT-IR
reflection spectroscopy. These silicone specimens did not deposit apatite or calcium phosphates, irrespective of chemical treatment. Osteoblast-like cells (MC3T3-El) derived from mouse were cultured on the specimens at 36.5Ž under 5%C0(2) and 95% humidity. Similar degree of proliferation of cells was observed at 7 days among three specimens, while the no treatment specimen after incubation for 5 days showed a lower degree of proliferation than the silicone treated with 30 wt% H(2)O(2) solutions with or without TaCl(5). Alkaline phosphatase activity of the cells proliferated on the no treatment specimen was lower than those of the silicone treated with 30 wt% H(2)O(2) solutions with or without
TaCl(5). These results indicate that the cytotoxicity of the silicone could be improved by the chemical treatment with 30 wt% H(2)O(2) solutions with or without TaCl(5).
en-copyright=
kn-copyright=

en-aut-name=HayakawaSatoshi
en-aut-sei=Hayakawa
en-aut-mei=Satoshi
kn-aut-name=‘μ‘
kn-aut-sei=‘μ
kn-aut-mei=‘
aut-affil-num=1
ORCID=

en-aut-name=ShirosakiYuki
en-aut-sei=Shirosaki
en-aut-mei=Yuki
kn-aut-name=ιθ—R‹I
kn-aut-sei=ιθ
kn-aut-mei=—R‹I
aut-affil-num=2
ORCID=

en-aut-name=YabutaTakeshi
en-aut-sei=Yabuta
en-aut-mei=Takeshi
kn-aut-name=βΦ“c•Ži
kn-aut-sei=βΦ“c
kn-aut-mei=•Ži
aut-affil-num=3
ORCID=

en-aut-name=TsuruKanji
en-aut-sei=Tsuru
en-aut-mei=Kanji
kn-aut-name=“s—―Š°Ž‘
kn-aut-sei=“s—―
kn-aut-mei=Š°Ž‘
aut-affil-num=4
ORCID=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=OhtsukiChikara
kn-aut-sei=Ohtsuki
kn-aut-mei=Chikara
aut-affil-num=5
ORCID=

en-aut-name=OsakaAkiyoshi
en-aut-sei=Osaka
en-aut-mei=Akiyoshi
kn-aut-name=”φβ–Ύ‹`
kn-aut-sei=”φβ
kn-aut-mei=–Ύ‹`
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=2
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=3
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=4
en-affil=
kn-affil=Department of Bioscience and Biotechnology

affil-num=5
en-affil=
kn-affil=Graduate School of Materials Science. Nara Institute of Science and Technology

affil-num=6
en-affil=
kn-affil=Department of Bioscience and Biotechnology
END