start-ver=1.4
cd-journal=joma
no-vol=62
cd-vols=
no-issue=5
article-no=
start-page=861
end-page=867
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210809
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Radon inhalation decreases DNA damage induced by oxidative stress in mouse organs via the activation of antioxidative functions
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Radon inhalation decreases the level of lipid peroxide (LPO); this is attributed to the activation of antioxidative functions. This activation contributes to the beneficial effects of radon therapy, but there are no studies on the risks of radon therapy, such as DNA damage. We evaluated the effect of radon inhalation on DNA damage caused by oxidative stress and explored the underlying mechanisms. Mice were exposed to radon inhalation at concentrations of 2 or 20 kBq/m(3) (for one, three, or 10 days). The 8-hydroxy-2 '-deoxyguanosine (8-OHdG) levels decreased in the brains of mice that inhaled 20 kBq/m(3) radon for three days and in the kidneys of mice that inhaled 2 or 20 kBq/m(3) radon for one, three or 10 days. The 8-OHdG levels in the small intestine decreased by approximately 20-40% (2 kBq/m(3) for three days or 20 kBq/m(3) for one, three or 10 days), but there were no significant differences in the 8-OHdG levels between mice that inhaled a sham treatment and those that inhaled radon. There was no significant change in the levels of 8-oxoguanine DNA glycosylase, which plays an important role in DNA repair. However, the level of Mn-superoxide dismutase (SOD) increased by 15-60% and 15-45% in the small intestine and kidney, respectively, following radon inhalation. These results suggest that Mn-SOD probably plays an important role in the inhibition of oxidative DNA damage.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=ShutoHina
en-aut-sei=Shuto
en-aut-mei=Hina
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NaoeShota
en-aut-sei=Naoe
en-aut-mei=Shota
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=YanoJunki
en-aut-sei=Yano
en-aut-mei=Junki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=KanzakiNorie
en-aut-sei=Kanzaki
en-aut-mei=Norie
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=TanakaHiroshi
en-aut-sei=Tanaka
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=TeratoHiroaki
en-aut-sei=Terato
en-aut-mei=Hiroaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
affil-num=1
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=2
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=3
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=4
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=5
en-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
kn-affil=
affil-num=6
en-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
kn-affil=
affil-num=7
en-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
kn-affil=
affil-num=8
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=9
en-affil=Graduate School ofMedicine Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=
affil-num=10
en-affil=Advanced Science Research Center Okayama University
kn-affil=
affil-num=11
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
en-keyword=radon
kn-keyword=radon
en-keyword=oxidative DNA damage
kn-keyword=oxidative DNA damage
en-keyword=Mn-superoxide dismutase (SOD)
kn-keyword=Mn-superoxide dismutase (SOD)
en-keyword=8-oxoguanine DNA glycosylase
kn-keyword=8-oxoguanine DNA glycosylase
END
start-ver=1.4
cd-journal=joma
no-vol=62
cd-vols=
no-issue=3
article-no=
start-page=390
end-page=400
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210127
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Evaluation of the redox state in mouse organs following radon inhalation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Radon inhalation activates antioxidative functions in mouse organs, thereby contributing to inhibition of oxidative stress-induced damage. However, the specific redox state of each organ after radon inhalation has not been reported. Therefore, in this study, we evaluated the redox state of various organs in mice following radon inhalation at concentrations of 2 or 20 kBq/m(3) for 1, 3 or 10 days. Scatter plots were used to evaluate the relationship between antioxidative function and oxidative stress by principal component analysis (PCA) of data from control mice subjected to sham inhalation. The results of principal component (PC) 1 showed that the liver and kidney had high antioxidant capacity; the results of PC2 showed that the brain, pancreas and stomach had low antioxidant capacities and low lipid peroxide (LPO) content, whereas the lungs, heart, small intestine and large intestine had high LPO content but low antioxidant capacities. Furthermore, using the PCA of each obtained cluster, we observed altered correlation coefficients related to glutathione, hydrogen peroxide and LPO for all groups following radon inhalation. Correlation coefficients related to superoxide dismutase in organs with a low antioxidant capacity were also changed. These findings suggested that radon inhalation could alter the redox state in organs; however, its characteristics were dependent on the total antioxidant capacity of the organs as well as the radon concentration and inhalation time. The insights obtained from this study could be useful for developing therapeutic strategies targeting individual organs.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KanzakiNorie
en-aut-sei=Kanzaki
en-aut-mei=Norie
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=ShutoHina
en-aut-sei=Shuto
en-aut-mei=Hina
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YanoJunki
en-aut-sei=Yano
en-aut-mei=Junki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NaoeShota
en-aut-sei=Naoe
en-aut-mei=Shota
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=TanakaHiroshi
en-aut-sei=Tanaka
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=TeratoHiroaki
en-aut-sei=Terato
en-aut-mei=Hiroaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
affil-num=1
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=2
en-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
kn-affil=
affil-num=3
en-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
kn-affil=
affil-num=4
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=5
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=6
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=7
en-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
kn-affil=
affil-num=8
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=9
en-affil=Advanced Science Research Center, Okayama University
kn-affil=
affil-num=10
en-affil=Graduate School ofMedicine Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=
affil-num=11
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
en-keyword=radon
kn-keyword=radon
en-keyword=redox state
kn-keyword=redox state
en-keyword=oxidative stress
kn-keyword=oxidative stress
en-keyword=antioxidative function
kn-keyword=antioxidative function
en-keyword=principal component analysis
kn-keyword=principal component analysis
END
start-ver=1.4
cd-journal=joma
no-vol=61
cd-vols=
no-issue=4
article-no=
start-page=517
end-page=523
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2020
dt-pub=20200429
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=X-Irradiation at 0.5 Gy after the forced swim test reduces forced swimming-induced immobility in mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The forced swim test (FST) is a screening model for antidepressant activity; it causes immobility and induces oxidative stress. We previously reported that radon inhalation has antidepressant-like effects in mice potentially through the activation of antioxidative functions upon radon inhalation. This study aimed to investigate the effect of prior and post low-dose X-irradiation (0.1, 0.5, 1.0 and 2.0 Gy) on FST-induced immobility and oxidative stress in the mouse brain, and the differences, if any, between the two. Mice received X-irradiation before or after the FST repeatedly for 5 days. In the post-FST-irradiated group, an additional FST was conducted 4h after the last irradiation. Consequently, animals receiving prior X-irradiation (0.1 Gy) had better mobility outcomes than sham-irradiated mice; however, their levels of lipid peroxide (LPO), an oxidative stress marker, remained unchanged. However, animals that received post-FST X-irradiation (0.5 Gy) had better mobility outcomes and their LPO levels were significantly lower than those of the sham-irradiated mice. The present results indicate that 0.5 Gy X-irradiation after FST inhibits FST-induced immobility and oxidative stress in mice.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=ShutoHina
en-aut-sei=Shuto
en-aut-mei=Hina
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=YanoJunki
en-aut-sei=Yano
en-aut-mei=Junki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=NaoeShota
en-aut-sei=Naoe
en-aut-mei=Shota
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=IshidaTsuyoshi
en-aut-sei=Ishida
en-aut-mei=Tsuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NakadaTetsuya
en-aut-sei=Nakada
en-aut-mei=Tetsuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=YamatoKeiko
en-aut-sei=Yamato
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=NomuraTakaharu
en-aut-sei=Nomura
en-aut-mei=Takaharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
affil-num=1
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=2
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=3
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=4
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=5
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=6
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=7
en-affil=Laboratory of Neurology and Neurosurgery, National Cerebral and Cardiovascular Center
kn-affil=
affil-num=8
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=9
en-affil=Central Research Institute of Electric Power Industry
kn-affil=
affil-num=10
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=
en-keyword=X-irradiation
kn-keyword=X-irradiation
en-keyword=forced swim test
kn-keyword=forced swim test
en-keyword=antioxidants
kn-keyword=antioxidants
en-keyword=brain
kn-keyword=brain
en-keyword=oxidative stress
kn-keyword=oxidative stress
END
start-ver=1.4
cd-journal=joma
no-vol=34
cd-vols=
no-issue=9
article-no=
start-page=1181
end-page=1187
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201210
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Comparative Study on the Inhibitory Effects of α-Tocopherol and Radon on Carbon Tetrachloride-Induced Renal Damage
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Since the 2011 nuclear accident in Fukushima, the effects of low-dose irradiation, especially internal exposure, are at the forefront of everyone’s attention. However, low-dose radiation induced various stimulating effects such as activation of antioxidative and immune functions. In this study, we attempted to evaluate the quantitative effects of the activation of antioxidative activities in kidney induced by radon inhalation on carbon tetrachloride (CCl4)-induced renal damage. Mice were subjected to intraperitoneal (i.p.) injection of CCl4 after inhaling approximately 1000 or 2000 Bq/m3 radon for 24 h, or immediately after i.p. injection of α-tocopherol (100, 300, or 500 mg/kg bodyweight). In case of renal function, radon inhalation at a concentration of 2000 Bq/m3 has the inhibitory effects similar to α-tocopherol treatment at a dose of 300?500 mg/kg bodyweight. The activities of superoxide dismutase and catalase in kidneys were significantly higher in mice exposed to radon as compared to mice treated with CCl4 alone. These findings suggest that radon inhalation has an antioxidative effect against CCl4-induced renal damage similar to the antioxidative effects of α-tocopherol due to induction of antioxidative functions.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=YamatoKeiko
en-aut-sei=Yamato
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=MoriiYuji
en-aut-sei=Morii
en-aut-mei=Yuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=EtaniReo
en-aut-sei=Etani
en-aut-mei=Reo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=TakataYuji
en-aut-sei=Takata
en-aut-mei=Yuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=KawabeAtsuishi
en-aut-sei=Kawabe
en-aut-mei=Atsuishi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=7
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=8
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=9
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=10
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=11
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=12
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=radon
kn-keyword=radon
en-keyword=carbon tetrachloride
kn-keyword=carbon tetrachloride
en-keyword=oxidative damage
kn-keyword=oxidative damage
en-keyword=α-tocopherol
kn-keyword=α-tocopherol
en-keyword=kidney
kn-keyword=kidney
END
start-ver=1.4
cd-journal=joma
no-vol=61
cd-vols=
no-issue=1
article-no=
start-page=1
end-page=8
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120127
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Basic Study on Positive Effects of Radon Inhalation on Pet's Health
kn-title=ラドン吸入がペットの健康改善に及ぼす効果に関する基礎的検討
en-subtitle=
kn-subtitle=
en-abstract=Radon inhalation using our radon exposure device activated anti-oxidative function in some organs of mouse. To assess the possibility of its application to veterinary care, healthy dogs and cats with chronic renal failure were inhaled radon at a concentration of 5500Bq/m3 for 30 minutes every 2 days for 30 days. In result, radon inhalation within a relatively long time period significantly decreased the triglyceride level of dogs. On the other hand, some cats increased the volume of drinking water by radon inhalation and the creatinine level in blood of these cats was decreased to normal level. These findings suggest that radon inhalation may have curative properties against chronic renal failure.
kn-abstract=著者らは今までに，共同開発したラドン吸入装置を用いマウスにラドン吸入をさせた場合，諸臓器中の抗酸化機能が亢進する可能性などを明らかにしてきた。本研究では，ラドン吸入の獣医療への応用の可能性について新たに検討するため，健常なイヌ5頭(オス：2(1，9才)，メス：3(1〜5才))及び慢性腎不全症のネコ8頭(オス：3(2〜6才)，メス：5(5〜7才))を対象に基礎的な検討をした。すなわち，約5500Bq/m3のラドンを1回30分で隔日に30日間(計15回)それぞれ吸入させた。その結果，イヌにおいて，中性脂肪が減少する可能性が示された。また，その効果は吸入開始20〜30日後に現れることも示唆できた。他方，ネコにおいて，飲水量が改善し血清中クレアチニンが基準値内に減少する症例がみられるなど，慢性腎不全症に対し一定の効果が期待できる可能性が示唆された。
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=片岡隆浩
kn-aut-sei=片岡
kn-aut-mei=隆浩
aut-affil-num=1
ORCID=
en-aut-name=TokunagaRikizo
en-aut-sei=Tokunaga
en-aut-mei=Rikizo
kn-aut-name=徳永力三
kn-aut-sei=徳永
kn-aut-mei=力三
aut-affil-num=2
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=迫田晃弘
kn-aut-sei=迫田
kn-aut-mei=晃弘
aut-affil-num=3
ORCID=
en-aut-name=KawabeAtsushi
en-aut-sei=Kawabe
en-aut-mei=Atsushi
kn-aut-name=川辺睦
kn-aut-sei=川辺
kn-aut-mei=睦
aut-affil-num=4
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=5
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=山岡聖典
kn-aut-sei=山岡
kn-aut-mei=聖典
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=2
en-affil=
kn-affil=南富士ケンネル附属動物病院
affil-num=3
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=4
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=5
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=6
en-affil=
kn-affil=岡山大学大学院保健学研究科
en-keyword=dog
kn-keyword=dog
en-keyword=cat
kn-keyword=cat
en-keyword=radon inhalation
kn-keyword=radon inhalation
en-keyword=serum biochemistry
kn-keyword=serum biochemistry
en-keyword=chronic renal failure
kn-keyword=chronic renal failure
END
start-ver=1.4
cd-journal=joma
no-vol=57
cd-vols=
no-issue=4
article-no=
start-page=241
end-page=251
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20080425
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Basic Study on Activation of Antioxidation Function in Some Organs of Mice by Radon Inhalation Using New Radon Exposure Device
kn-title=ラドン吸入試作装置によるマウス諸臓器中の抗酸化機能の亢進に関する研究
en-subtitle=
kn-subtitle=
en-abstract=There are a lot of life style diseases that are related to reactive oxygen species in indications of the radon therapy, and, the further clarification of mechanism is expected. Therefore, in this study, we investigated the activation of antioxidation function in some organs of mice by radon inhalation using the new radon exposure device. It was enable that this device was the adjustments of radon concentration by changing the air flow rate to the specially processed radon source and so on. The mice were made to inhale the radon of 400Bq/m3 or 4000Bq/m3 with this device. Results show that in brain, lungs, liver, and kidney, both the activities of superoxide dismutase(SOD) and catalase increased, and lipid peroxide levels decreased. This suggests that radon inhalation enhanced the antioxidation function. These findings are important in understanding the mechanism of diseases in which radon therapy is used as treatment, and most of which are called activated oxygen-related diseases.
kn-abstract=ラドン療法の適応症には活性酸素に由来する生活習慣病が多く，その機構の更なる解明が期待されている。また，汎用性があり医学的効果が再現できるラドン吸入装置の構築は意義が大きい。このため，著者らは共同で開発したラドン吸入試作装置を用い，マウス諸臓器中の抗酸化機能の変化特性を検討した。ラドン吸入試作装置は，特殊加工したラドン線源を収納したユニットの数量，それへの送風量及び湿度などを調節することによりラドン濃度を自在に調整可能にするものである。この装置によりマウスに400Bq/m3あるいは4000Bq/m3のラドンを吸入させた。その結果，脳・肺・肝臓・腎臓において，抗酸化系酵素であるSODとカタラーゼの両活性が増加し，過酸化脂質量が減少した。この抗酸化機能の亢進により，本実験条件でのラドン吸入は活性酸素障害の抑制，すなわち，生活習慣病の予防や症状緩和に効果のある可能性が改めて示唆できた。
en-copyright=
kn-copyright=
en-aut-name=NakagawaShinya
en-aut-sei=Nakagawa
en-aut-mei=Shinya
kn-aut-name=中川慎也
kn-aut-sei=中川
kn-aut-mei=慎也
aut-affil-num=1
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=片岡隆浩
kn-aut-sei=片岡
kn-aut-mei=隆浩
aut-affil-num=2
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=迫田晃弘
kn-aut-sei=迫田
kn-aut-mei=晃弘
aut-affil-num=3
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=石森有
kn-aut-sei=石森
kn-aut-mei=有
aut-affil-num=4
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=5
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=山岡聖典
kn-aut-sei=山岡
kn-aut-mei=聖典
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=2
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=3
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=4
en-affil=
kn-affil=独立行政法人 日本原子力研究開発機構人形峠環境技術センター
affil-num=5
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=6
en-affil=
kn-affil=岡山大学大学院保健学研究科
en-keyword=new radon exposure device
kn-keyword=new radon exposure device
en-keyword=radon inhalation
kn-keyword=radon inhalation
en-keyword=antioxidative function
kn-keyword=antioxidative function
en-keyword=superoxide dismutase
kn-keyword=superoxide dismutase
en-keyword=catalase
kn-keyword=catalase
en-keyword=lipid peroxide
kn-keyword=lipid peroxide
en-keyword=active oxygen
kn-keyword=active oxygen
en-keyword=mouse
kn-keyword=mouse
en-keyword=radon-222
kn-keyword=radon-222
END
start-ver=1.4
cd-journal=joma
no-vol=146
cd-vols=
no-issue=1-3
article-no=
start-page=360
end-page=363
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=201107
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Our previous studies showed the possibility that activation of the antioxidative function alleviates various oxidative damages, which are related to lifestyle diseases. Results showed that, low-dose X-ray irradiation activated superoxide dismutase and inhibits oedema following ischaemia-reperfusion. To alleviate ischaemia-reperfusion injury with transplantation, the changes of the antioxidative function in liver graft using low-dose X-ray irradiation immediately after exenteration were examined. Results showed that liver grafts activate the antioxidative function as a result of irradiation. In addition, radon inhalation enhances the antioxidative function in some organs, and alleviates alcohol-induced oxidative damage of mouse liver. Moreover, in order to determine the most effective condition of radon inhalation, mice inhaled radon before or after carbon tetrachloride (CCl4) administration. Results showed that radon inhalation alleviates CCl4-induced hepatopathy, especially prior inhalation. It is highly possible that adequate activation of antioxidative functions induced by low-dose irradiation can contribute to preventing or reducing oxidative damages, which are related to lifestyle diseases.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=YoshimotoMasaaki
en-aut-sei=Yoshimoto
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=NakagawaShinya
en-aut-sei=Nakagawa
en-aut-mei=Shinya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=ToyotaTeruaki
en-aut-sei=Toyota
en-aut-mei=Teruaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=YamatoKeiko
en-aut-sei=Yamato
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=KawabeAtsushi
en-aut-sei=Kawabe
en-aut-mei=Atsushi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Sakakibara Heart Institute of Okayama
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=7
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=8
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center
affil-num=9
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=10
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=11
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=12
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
END
start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=1
article-no=
start-page=21
end-page=24
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=The Elevation of p53 Protein Level and SOD Activity in the Resident Blood of the Misasa Radon Hot Spring District
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To clarify the mechanism by which radon hot springs prevent cancer or not, in this study, blood was collected from residents in the Misasa hot spring district and in a control district. The level of a representative cancer-suppressive gene, p53, and the activity of a representative antioxidant enzyme, superoxide dismutase (SOD), were analyzed as indices. The level of serum p53 protein in the males in the Misasa hot spring district was found to be 2-fold higher than that in the control district, which is a significant difference. In the females in the Misasa hot spring district, SOD activity was approximately 15% higher than that in the control district, which is also statistically significant, and exceeded the reference range of SOD activity despite advanced age. These results suggested that routine exposure of the residents in the Misasa hot spring district to radon at a concentration about 3 times higher than the national mean induces trace active oxygen in vivo, potentiating products of cancer-suppressive gene and antioxidant function. As the p53 protein level was high in the residents in the Misasa hot spring district, apoptosis of cancer cells may readily occur.
en-copyright=
kn-copyright=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=MitsunobuFumihiro
en-aut-sei=Mitsunobu
en-aut-mei=Fumihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=KojimaShuji
en-aut-sei=Kojima
en-aut-mei=Shuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=ShibakuraMisako
en-aut-sei=Shibakura
en-aut-mei=Misako
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
affil-num=1
en-affil=
kn-affil=Departments of Radiological Technology, Okayama University Medical School
affil-num=2
en-affil=
kn-affil=Misasa Medical Center, Okayama University Medical School
affil-num=3
en-affil=
kn-affil=Faculty of Pharmaceutical Sciences, Science University of Tokyo
affil-num=4
en-affil=
kn-affil=Departments of Medical Technology, Okayama University Medical School
affil-num=5
en-affil=
kn-affil=Departments of Radiological Technology, Okayama University Medical School
affil-num=6
en-affil=
kn-affil=Departments of Radiological Technology, Okayama University Medical School
affil-num=7
en-affil=
kn-affil=Misasa Medical Center, Okayama University Medical School
en-keyword=Radon hot spring
kn-keyword=Radon hot spring
en-keyword=Misasa
kn-keyword=Misasa
en-keyword=Cancer-related mortality rate
kn-keyword=Cancer-related mortality rate
en-keyword=p53 protein level
kn-keyword=p53 protein level
en-keyword=Superoxide dismutase activity
kn-keyword=Superoxide dismutase activity
END
start-ver=1.4
cd-journal=joma
no-vol=45
cd-vols=
no-issue=1
article-no=
start-page=89
end-page=95
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040507
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Inhibitory Effects of Prior Low-dose X-ray Irradiation on Carbon Tetrachloride-induced Hepatopathy in Acatalasemic Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The catalase activities in blood and organs of the acatalasemic (C3H/AnLCsbCsb) mouse of C3H strain are lower than those of the normal (C3H/AnLCsaCsa) mouse. We examined the effects of prior low-dose (0.5 Gy) X-ray irradiation, which reduced the oxidative damage under carbon tetrachloride-induced hepatopathy in the acatalasemic or normal mice. The acatalasemic mice showed a significantly lower catalase activity and a significantly higher glutathione peroxidase activity compared with those in the normal mice. Moreover, low-dose irradiation increased the catalase activity in the acatalasemic mouse liver to a level similar to that of the normal mouse liver. Pathological examinations and analyses of blood glutamic oxaloacetic and glutamic pyruvic transaminase activity and lipid peroxide levels showed that carbon tetrachloride induced hepatopathy was inhibited by low-dose irradiation. These findings may indicate that the free radical reaction induced by the lack of catalase and the administration of carbon tetrachloride is more properly neutralized by high glutathione peroxidase activity and low-dose irradiation in the acatalasemic mouse liver.
en-copyright=
kn-copyright=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NomuraTakaharu
en-aut-sei=Nomura
en-aut-mei=Takaharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=WangDa-Hong
en-aut-sei=Wang
en-aut-mei=Da-Hong
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=MoriShuji
en-aut-sei=Mori
en-aut-mei=Shuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=KiraShohei
en-aut-sei=Kira
en-aut-mei=Shohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=2
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=3
en-affil=
kn-affil=Low Dose Radiation Research Center, Central Research Institute of Electric Power Industry
affil-num=4
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=5
en-affil=
kn-affil=Public Health, Okayama University Medical School
affil-num=6
en-affil=
kn-affil=Pharmacology, Okayama University Medical School
affil-num=7
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=8
en-affil=
kn-affil=Public Health, Okayama University Medical School
en-keyword=Acatalasemic mouse
kn-keyword=Acatalasemic mouse
en-keyword=Catalase
kn-keyword=Catalase
en-keyword=CCl4
kn-keyword=CCl4
en-keyword=Hepatotoxicity
kn-keyword=Hepatotoxicity
en-keyword=Low-dose X-irradiation
kn-keyword=Low-dose X-irradiation
en-keyword=Antioxidant substances
kn-keyword=Antioxidant substances
END
start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=5
article-no=
start-page=648
end-page=652
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=200805
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Radioactivity and radon emanation fraction of the granites sampled at Misasa and Badgastein
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The chemical composition was analyzed and the radioactivity, radon exhalation rate and emanation fraction were measured to investigate the characteristics of the granites sampled at Misasa and Badgastein, world famous for radon therapy. The Misasa granite was probably composed of quartz, albite and microcline. The Badgastein granite was probably composed of quartz and muscovite. The radon exhalation rates and emanation fractions of the Misasa granite were much higher than those of the Badgastein granite, regardless of the Ra-226 activity concentrations.
en-copyright=
kn-copyright=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=IshimoriYu
en-aut-sei=Ishimori
en-aut-mei=Yu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=NagamatsuTomohiro
en-aut-sei=Nagamatsu
en-aut-mei=Tomohiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=radioactivity
kn-keyword=radioactivity
en-keyword=radon emanation fraction
kn-keyword=radon emanation fraction
en-keyword=granite
kn-keyword=granite
en-keyword=Misasa
kn-keyword=Misasa
en-keyword=Badgastein
kn-keyword=Badgastein
END
start-ver=1.4
cd-journal=joma
no-vol=43
cd-vols=
no-issue=1
article-no=
start-page=106
end-page=110
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=20080623
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Effects of some physical conditions on leaching rate of radon from radioactive minerals originating from some hot springs
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In order to determine the best physical conditions for leaching more radon from minerals into water, we measured the leaching rate of radon from radioactive minerals under the conditions of some different grain sizes and water temperatures. Water temperature affected the leaching rate of radon although the grain size did not significantly affect it. Furthermore, we proposed ultrasonic irradiation to the mixture of a mineral and water as the method of leaching more radon. Ultrasonic irradiation was efficient to leach more radon from the mineral soaked in water because of ultrasonic cavitation.
en-copyright=
kn-copyright=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=NagamatsuTomohiro
en-aut-sei=Nagamatsu
en-aut-mei=Tomohiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=radon hot spring
kn-keyword=radon hot spring
en-keyword=radioactive mineral
kn-keyword=radioactive mineral
en-keyword=leaching
kn-keyword=leaching
en-keyword=grain size
kn-keyword=grain size
en-keyword=water temperature
kn-keyword=water temperature
en-keyword=ultrasonic irradiation
kn-keyword=ultrasonic irradiation
END
start-ver=1.4
cd-journal=joma
no-vol=13
cd-vols=
no-issue=1
article-no=
start-page=7
end-page=15
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=20021225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Recent trend of research on the adaptive response induced by low dose radiation and its significance
kn-title=低線量放射線の適応応答に関する最近の研究動向とその意義
en-subtitle=
kn-subtitle=
en-abstract=We reviewed the recent trend of research on the adaptive response induced by low dose radiation and its significance. The following view were obtained. Risk assessment is fundamental to the protection of public health from radiation exposure, but any estimate of risk is subject to numerous major uncertainties. In view of the uncertainties surrounding the shape of dose-response curves at low doses of ionizing radiation. the linear nonthreshold dose-response model is now widely accepted as a paradigm in radiation protection practice and risk analysis. However, interest among scientists in obtaining a more conclusive understanding of the effects of low dose radiation has been evident in recent initiatives, such as adaptive response of low dose radiation, in part to help verify or disprove the linear model. A vigorous worldwide effort is now apparently underway to understand the basic mechanisms underlying the biological effects of low dose radiation. This review presents a series of papers representing the progress going on, which will undoubtably make an important contribution to this field of research.
kn-abstract=本総説は,低線量放射線に対する生体の適応応答(以下,適応応答)に関してその効果を含む最近の研究動向,さらに放射線防護との関係についてまとめたものである｡特にこの分野で最も検討が進んでいる｢低線量放射線照射の生物学的影響｣に関する国際研究組織(BELLE)での動向を中心に報告するものである｡即ち,ヒトと自然放射線との共存などヒトの生活環境と適応応答について,適応応答の短期的･長期的効果など適応応答の効果とその生物学的意義について言及した｡次に,適応応答の医療などへの応用の可能性について,また,適応応答と放射線防護との関係についても言及した｡ここで,低線量放射線にはヒトへの有益な効果があるとの多くの報告例がある半面,放射線防護の面では微量放射線でも危険とする考え方がその根拠にあることがわかった｡このため,今後は更なる低線量放射線の生体影響研究を進めるとともに,両者の間の隙間をなくす現実的･合理的な対応が求められている｡
en-copyright=
kn-copyright=
en-aut-name=KusuharaToshimasa
en-aut-sei=Kusuhara
en-aut-mei=Toshimasa
kn-aut-name=楠原俊昌
kn-aut-sei=楠原
kn-aut-mei=俊昌
aut-affil-num=1
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=2
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=山岡聖典
kn-aut-sei=山岡
kn-aut-mei=聖典
aut-affil-num=3
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=3
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
en-keyword=低線量放射線 (low dose radiation)
kn-keyword=低線量放射線 (low dose radiation)
en-keyword=低濃度化学物質 (low dose chemicals)
kn-keyword=低濃度化学物質 (low dose chemicals)
en-keyword=適応応答 (adaptive response)
kn-keyword=適応応答 (adaptive response)
en-keyword=放射線ホルミシス (radiation hormesis)
kn-keyword=放射線ホルミシス (radiation hormesis)
en-keyword=放射線防護 (radiation protection)
kn-keyword=放射線防護 (radiation protection)
END
start-ver=1.4
cd-journal=joma
no-vol=13
cd-vols=
no-issue=2
article-no=
start-page=77
end-page=82
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=20030320
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A Study of Reconstruction of Magnetic Resonance Image
kn-title=MRIにおける画像の再構成
en-subtitle=
kn-subtitle=
en-abstract=Magnetic resonance is an important modality for medical imaging, and advanced mathematical techniques are introduced into the reconstruction of images. Clearly
understandable explanations of the reconstruction of the MR image and of the mathematical derivation process have not been presented in the texts. Reconstruction of MR image is presented using the complex function and its relevant Fourier coefficients.
kn-abstract=磁気共鳴は医学におけるイメージングにおいて重要なモダリティーであり,高度な数学的手法が画像の再構成に取り入れられている｡画像再構成の数学的手法および画像再構成にいたるまでの数学的な過程を理解するこは,MRIを学ぶものにとって非常に重要であるが,成書において明確な説明はなされていない｡ここでは,MR画像の再構成法を,複素関数と複素フ-リェ係数を用いて導いたので報告する｡
en-copyright=
kn-copyright=
en-aut-name=KatoHirokazu
en-aut-sei=Kato
en-aut-mei=Hirokazu
kn-aut-name=加藤博和
kn-aut-sei=加藤
kn-aut-mei=博和
aut-affil-num=1
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=2
ORCID=
en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=黒田昌宏
kn-aut-sei=黒田
kn-aut-mei=昌宏
aut-affil-num=3
ORCID=
en-aut-name=ShibuyaKoichi
en-aut-sei=Shibuya
en-aut-mei=Koichi
kn-aut-name=澁谷光一
kn-aut-sei=澁谷
kn-aut-mei=光一
aut-affil-num=4
ORCID=
en-aut-name=KawasakiShoji
en-aut-sei=Kawasaki
en-aut-mei=Shoji
kn-aut-name=川崎祥二
kn-aut-sei=川崎
kn-aut-mei=祥二
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻医用放射線科学講座
affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻医用放射線科学講座
affil-num=3
en-affil=
kn-affil=岡山大学医学部付属病院
affil-num=4
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻医用放射線科学講座
affil-num=5
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻医用放射線科学講座
en-keyword=MRI
kn-keyword=MRI
en-keyword=フーリェ変換 (Fourier transform)
kn-keyword=フーリェ変換 (Fourier transform)
en-keyword=画像再構成 (Reconstruction)
kn-keyword=画像再構成 (Reconstruction)
en-keyword=周波数エンコード (Frequency encode)
kn-keyword=周波数エンコード (Frequency encode)
en-keyword=位相画像 (Phase image)
kn-keyword=位相画像 (Phase image)
END
start-ver=1.4
cd-journal=joma
no-vol=14
cd-vols=
no-issue=1
article-no=
start-page=1
end-page=14
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2003
dt-pub=20031225
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Recent trend of research on the nongenotoxic mechanisms of chemical carcinogenesis
kn-title=化学発がんの非遺伝毒性的メカニズムの解明に関する最近の動向
en-subtitle=
kn-subtitle=
en-abstract=To elucidate the health effects by low dose radiation, we reviewed the recent trend of research on the epigenetic mechanisms of chemical carcinogenesis. The following view were obtained. It has become apparent that chemical and physical agents that induce cancer may do so through different cellular and molecular mechanisms. Investigators, recognizing the apparent differences in the ways compounds
participate in the carcinogenesis process, coined the phrases "genotoxic" and "epigenetic" in describing activities of chemicals and physical agents that induced
cancer. The term "nongenotoxic" has to some extent replaced "epigenetic" and thus, classification of chemical carcinogens has been frequently delegated to either the genotoxic or nongenotoxic categories. Moreover, while much work remains in the understanding of the modes and mechanisms of action of nongenotoxic carcinogens and the epigenetic effects of these agents, it is apparent that this category of chemicals are functionally different than those compounds which directly interact, mutate, and modify genomic DNA.
kn-abstract=本総説は,筆者らが進めている｢低線量放射線の健康への影響と医療への応用｣に関する研究に資するために調査した,化学発がんの非遺伝毒性的メカニズムの解明に関する最近の動向の概要についてまとめたものである｡即ち,非遺伝毒性的発がんにおける細胞増殖,シトクロムP450誘導,酸化的ストレス,および遺伝子発現のそれぞれの役割,並びに量的な応答性について言及した｡また,後成的発がんにおけるアポトーシス,およびギャップ結合による情報伝達のそれぞれの役割についても触れた｡その結果,非遺伝毒性的な発がん物質の作用の様式とメカニズムやこれによる後成的な影響などについては解明さ
れつつあり,特に,これらの発がん物質がゲノムDNAに対し直接的な相互作用,突然変異,修飾などを行う発がん物質とは機能的に異なった作用をすることが明らかになった｡また,これらは放射線発がんなど低線量放射線の健康への影響などについて研究する上で,重要な知見となっていることもわかった。
en-copyright=
kn-copyright=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=山岡聖典
kn-aut-sei=山岡
kn-aut-mei=聖典
aut-affil-num=1
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=2
ORCID=
en-aut-name=InaYasuhiro
en-aut-sei=Ina
en-aut-mei=Yasuhiro
kn-aut-name=稲恭宏
kn-aut-sei=稲
kn-aut-mei=恭宏
aut-affil-num=3
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=片岡隆浩
kn-aut-sei=片岡
kn-aut-mei=隆浩
aut-affil-num=4
ORCID=
en-aut-name=KawabeAtsusi
en-aut-sei=Kawabe
en-aut-mei=Atsusi
kn-aut-name=川辺睦
kn-aut-sei=川辺
kn-aut-mei=睦
aut-affil-num=5
ORCID=
en-aut-name=SanoMasanobu
en-aut-sei=Sano
en-aut-mei=Masanobu
kn-aut-name=佐野正展
kn-aut-sei=佐野
kn-aut-mei=正展
aut-affil-num=6
ORCID=
en-aut-name=UjifukuAyako
en-aut-sei=Ujifuku
en-aut-mei=Ayako
kn-aut-name=氏福亜矢子
kn-aut-sei=氏福
kn-aut-mei=亜矢子
aut-affil-num=7
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=3
en-affil=
kn-affil=電力中央研究所低線量放射線研究センター
affil-num=4
en-affil=
kn-affil=岡山大学大学院保健学研究科保健学専攻修士課程
affil-num=5
en-affil=
kn-affil=岡山大学大学院保健学研究科保健学専攻修士課程
affil-num=6
en-affil=
kn-affil=岡山大学大学院保健学研究科保健学専攻修士課程
affil-num=7
en-affil=
kn-affil=岡山大学大学院保健学研究科保健学専攻修士課程
en-keyword=化学発がん (chemical carcinogenesis)
kn-keyword=化学発がん (chemical carcinogenesis)
en-keyword=非遺伝毒性 (nongenotoxicity)
kn-keyword=非遺伝毒性 (nongenotoxicity)
en-keyword=後成説 (epigenesis)
kn-keyword=後成説 (epigenesis)
en-keyword=酸化的ストレス (oxidative stress)
kn-keyword=酸化的ストレス (oxidative stress)
en-keyword=ギャップ結合 (gap junction)
kn-keyword=ギャップ結合 (gap junction)
END
start-ver=1.4
cd-journal=joma
no-vol=14
cd-vols=
no-issue=2
article-no=
start-page=121
end-page=128
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Measurement of sampling time in MRI and reconstruction of MR image
kn-title=MRIにおけるサンプリング時間の測定と画像の再構成
en-subtitle=
kn-subtitle=
en-abstract=Regarding the construction of k-space in MRI, it is necessary to extract the required data from the echo signals with the rate of sampling time. In order to measure
the sampling time, a rectangular phantom was placed on the left side of the FOV in the body coil of an MRI equipment, and got analog signals in the sequence of spin echo. The sampling time was determined by comparing the measured
signals with the Fourier coefficients obtained by transforming the step function which was similar to the profile of the FOV. The MRI MULTI-TEST PHANTOM was scanned, and the k-space was constructed with the extracted data from the echo signals with the rate of the determined sampling time. The MRI images of the MULTI-TEST PHANTOM were reconstructed by inverse-transforming the
obtained k-space.
kn-abstract=MRIにおいてk-spaceを構築するためにはエコー信号をサンプリング時間に従って採取する必要がある.このサンプリング時間を測定するために,FOV(field of view)の左半分にファントムを置くことにより階段関数となるスピン分布を生成した｡得られたエコー信号を,階段関数をフ-リェ変換したときに得られるフ-リェ係数と比較することによりサンプリング時間を求めた｡得られたサンプリング時間を用いて,MRI MULTI-TEST PHANTOMをMRI装置でスキャンすることにより得られたエコー信号をサンプリングしk-spaceを構築した。このk-spaceをフ-リェ逆変換することによりMRI MULTI-TEST PHANTOMの画像を再構成することができた。
en-copyright=
kn-copyright=
en-aut-name=KatoHirokazu
en-aut-sei=Kato
en-aut-mei=Hirokazu
kn-aut-name=加藤博和
kn-aut-sei=加藤
kn-aut-mei=博和
aut-affil-num=1
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=2
ORCID=
en-aut-name=KawasakiShoji
en-aut-sei=Kawasaki
en-aut-mei=Shoji
kn-aut-name=川崎祥二
kn-aut-sei=川崎
kn-aut-mei=祥二
aut-affil-num=3
ORCID=
en-aut-name=ShibuyaKoichi
en-aut-sei=Shibuya
en-aut-mei=Koichi
kn-aut-name=澁谷光一
kn-aut-sei=澁谷
kn-aut-mei=光一
aut-affil-num=4
ORCID=
en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=黒田昌宏
kn-aut-sei=黒田
kn-aut-mei=昌宏
aut-affil-num=5
ORCID=
en-aut-name=KoyamaTadashi
en-aut-sei=Koyama
en-aut-mei=Tadashi
kn-aut-name=小山矩
kn-aut-sei=小山
kn-aut-mei=矩
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=2
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=3
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=4
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院
affil-num=6
en-affil=
kn-affil=広島県立保健福祉大学放射線学科
en-keyword=MRI
kn-keyword=MRI
en-keyword=フーリェ変換 (Fourier transform)
kn-keyword=フーリェ変換 (Fourier transform)
en-keyword=画像再構成 (reconstruction)
kn-keyword=画像再構成 (reconstruction)
en-keyword=サンプリング時間 (sampling time)
kn-keyword=サンプリング時間 (sampling time)
END
start-ver=1.4
cd-journal=joma
no-vol=27
cd-vols=
no-issue=
article-no=
start-page=11
end-page=16
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=200512
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Basic study on the effects of the archeological investigation and the construction work
on the environmental radiation
kn-title=埋蔵文化財発掘調査および建設工事が環境放射線に及ぼす影響に関する基礎的検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In this paper, we investigated how the excavation of ruins and the construction work affected the environmental radiation in the Shikata campus of Okayama University (S-campus). The environmental radiation was steady in the S-campus until 1997, but began to change since 1998, while the ruin's survey and the construction work started frequently after 1998 in the S-campus. In general, the soil and the concrete include the natural radioisotope (uranium series and thorium series, etc). When ruins are surveyed, it is necessary to move a large amount of the soil. In addition, a large amount of the concrete is used for the construction work. To measure the environmental radiation, the monitor posts were set up on the east and west sides of the building of the Radioisotope Center (RIC). We sampled the soil in the container in each place. We used the high-purity germanium detector to analyze them. The monitor posts showed the difference in the in-air dose rate in each place in the S-campus. The in-air dose rate at the east side of the RIC was higher than that at the west side. The result of analysis showed that the soil includes the (40)K at the east side. While the specific activity of the 40K was 0.849Bq/g at the east side, the (40)K was hardly detected in the soil at the west side. The each soil included the 214-lead and 214-bismus ((214)Pb, (214)Bi), however, there was no significant difference in the specific activity of the each soil. The concrete included (40)K, whose specific activity was 0.492Bq/g. It was suggested that the change of the environmental radiation was attributed to radon and its daughter nuclides in the soil rather than the radiation from the concrete in the buildings.
en-copyright=
kn-copyright=
en-aut-name=NagamatsuTomohiro
en-aut-sei=Nagamatsu
en-aut-mei=Tomohiro
kn-aut-name=永松知洋
kn-aut-sei=永松
kn-aut-mei=知洋
aut-affil-num=1
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=2
ORCID=
en-aut-name=OnoToshiro
en-aut-sei=Ono
en-aut-mei=Toshiro
kn-aut-name=小野俊朗
kn-aut-sei=小野
kn-aut-mei=俊朗
aut-affil-num=3
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=山岡聖典
kn-aut-sei=山岡
kn-aut-mei=聖典
aut-affil-num=4
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学自然生命科学研究支援センター
affil-num=2
en-affil=
kn-affil=岡山大学医学部
affil-num=3
en-affil=
kn-affil=岡山大学自然生命科学研究支援センター
affil-num=4
en-affil=
kn-affil=岡山大学医学部
en-keyword=archeological investigation
kn-keyword=archeological investigation
en-keyword=construction work
kn-keyword=construction work
en-keyword=environmental radiation
kn-keyword=environmental radiation
en-keyword=soil
kn-keyword=soil
en-keyword=concrete
kn-keyword=concrete
END
start-ver=1.4
cd-journal=joma
no-vol=30
cd-vols=
no-issue=
article-no=
start-page=33
end-page=37
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=200812
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=岡山大学における核燃料物質の安全管理のための劣化ウランと天然ウランの鑑別について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In Japan, the Law for the Regulation of Nuclear Source Materials, Nuclear Fuel Materials and Reactors (Regulation Law) controls the nuclear fuel materials such as thorium (Th), uranium (U) and plutonium (Pu). Under the Regulation Law, all related materials and reactors are needed to register to the Government. In Okayama University, many nuclear fuel materials, mainly uranium compounds, are registered and stored in 11 departments, separately. Discrimination between depleted uranium and natural uranium is important for the observance of the Regulation Law and the safety management of the nuclear fuel materials in the Okayama University. However, the discrimination of the two kind of uranium has poorly analyzed. In this study, we analyzed several uranium compounds by using γ-ray spectrometry to determine whether the depleted uranium or not.
en-copyright=
kn-copyright=
en-aut-name=NagamatsuTomohiro
en-aut-sei=Nagamatsu
en-aut-mei=Tomohiro
kn-aut-name=永松知洋
kn-aut-sei=永松
kn-aut-mei=知洋
aut-affil-num=1
ORCID=
en-aut-name=HanafusaTadashi
en-aut-sei=Hanafusa
en-aut-mei=Tadashi
kn-aut-name=花房直志
kn-aut-sei=花房
kn-aut-mei=直志
aut-affil-num=2
ORCID=
en-aut-name=KinnoIkuo
en-aut-sei=Kinno
en-aut-mei=Ikuo
kn-aut-name=金野郁雄
kn-aut-sei=金野
kn-aut-mei=郁雄
aut-affil-num=3
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=迫田晃弘
kn-aut-sei=迫田
kn-aut-mei=晃弘
aut-affil-num=4
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=花元克巳
kn-aut-sei=花元
kn-aut-mei=克巳
aut-affil-num=5
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=山岡聖典
kn-aut-sei=山岡
kn-aut-mei=聖典
aut-affil-num=6
ORCID=
en-aut-name=OnoToshiro
en-aut-sei=Ono
en-aut-mei=Toshiro
kn-aut-name=小野俊朗
kn-aut-sei=小野
kn-aut-mei=俊朗
aut-affil-num=7
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=2
en-affil=
kn-affil=岡山大学自然生命科学研究支援センター光・放射線情報解析部門鹿田施設
affil-num=3
en-affil=
kn-affil=岡山大学自然生命科学研究支援センター光・放射線情報解析部門鹿田施設
affil-num=4
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=5
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=6
en-affil=
kn-affil=岡山大学大学院保健学研究科
affil-num=7
en-affil=
kn-affil=岡山大学自然生命科学研究支援センター光・放射線情報解析部門鹿田施設
en-keyword=Nuclear Fuel Materials
kn-keyword=Nuclear Fuel Materials
en-keyword=Depleted Uranium
kn-keyword=Depleted Uranium
en-keyword=Natural Uranium
kn-keyword=Natural Uranium
en-keyword=γ-ray Spectrometry
kn-keyword=γ-ray Spectrometry
END