start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=1-2 article-no= start-page=29 end-page=38 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The reconstructive surgery of head and neck cancers kn-title=頭頸部癌の再建外科―当科における再建術式の臨床的観察― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Thiry nine reconstructive surgeries were performed in 37 cases of head and neck cancers from January, 1989 to August, 1991 in our department. The best functional results were obtained on deglutition, swallowing and phonatin after intraoral and/or mesopharyngeal reconstruction using free radial forearm flaps. The free jejunal transposition procedure had the lowest complication rate. The rectus abdominus musculocutaneous free flap was used for nasal, paranasal reconstruction. Esthetics could be presereved by this reconstruction method due to mider postoperative atrophy and contraction. Eye sockets for the artificial eyes were made with eye conjunctiva in 3 canses of extended total maxillectomy with the orbital exenteration. The use of microvas-cular free flaps in this new plastic surgery resulted in the decrease of refusal of operations in maxillectomy canses. en-copyright= kn-copyright= en-aut-name=WatanabeShuichi en-aut-sei=Watanabe en-aut-mei=Shuichi kn-aut-name=渡辺周一 kn-aut-sei=渡辺 kn-aut-mei=周一 aut-affil-num=1 ORCID= en-aut-name=KawakamiTakashi en-aut-sei=Kawakami en-aut-mei=Takashi kn-aut-name=川上登史 kn-aut-sei=川上 kn-aut-mei=登史 aut-affil-num=2 ORCID= en-aut-name=InokuchiIkuo en-aut-sei=Inokuchi en-aut-mei=Ikuo kn-aut-name=井口郁雄 kn-aut-sei=井口 kn-aut-mei=郁雄 aut-affil-num=3 ORCID= en-aut-name=UnoKin-ya en-aut-sei=Uno en-aut-mei=Kin-ya kn-aut-name=宇野鉄哉 kn-aut-sei=宇野 kn-aut-mei=鉄哉 aut-affil-num=4 ORCID= en-aut-name=OhomichiTakuya en-aut-sei=Ohomichi en-aut-mei=Takuya kn-aut-name=大道卓也 kn-aut-sei=大道 kn-aut-mei=卓也 aut-affil-num=5 ORCID= en-aut-name=FukazawaMotoharu en-aut-sei=Fukazawa en-aut-mei=Motoharu kn-aut-name=深沢元晴 kn-aut-sei=深沢 kn-aut-mei=元晴 aut-affil-num=6 ORCID= en-aut-name=YonedaTakaaki en-aut-sei=Yoneda en-aut-mei=Takaaki kn-aut-name=米田孝明 kn-aut-sei=米田 kn-aut-mei=孝明 aut-affil-num=7 ORCID= en-aut-name=FukushimaKunihiro en-aut-sei=Fukushima en-aut-mei=Kunihiro kn-aut-name=福島邦博 kn-aut-sei=福島 kn-aut-mei=邦博 aut-affil-num=8 ORCID= en-aut-name=MasudaYu en-aut-sei=Masuda en-aut-mei=Yu kn-aut-name=増田游 kn-aut-sei=増田 kn-aut-mei=游 aut-affil-num=9 ORCID= en-aut-name=KamikawaYasuaki en-aut-sei=Kamikawa en-aut-mei=Yasuaki kn-aut-name=上川康明 kn-aut-sei=上川 kn-aut-mei=康明 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=再建外科 kn-keyword=再建外科 en-keyword=頭頸部癌 kn-keyword=頭頸部癌 en-keyword=有茎 (筋) 皮弁 kn-keyword=有茎 (筋) 皮弁 en-keyword=遊離 (筋) 皮弁 kn-keyword=遊離 (筋) 皮弁 END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=2 article-no= start-page=155 end-page=159 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Approaches for infantile hearing loss：Transmission from Okayama to other prefectures kn-title=小児難聴に対する取り組み―岡山から全国への発信― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KataokaYuko en-aut-sei=Kataoka en-aut-mei=Yuko kn-aut-name=片岡祐子 kn-aut-sei=片岡 kn-aut-mei=祐子 aut-affil-num=1 ORCID= en-aut-name=FukushimaKunihiro en-aut-sei=Fukushima en-aut-mei=Kunihiro kn-aut-name=福島邦博 kn-aut-sei=福島 kn-aut-mei=邦博 aut-affil-num=2 ORCID= en-aut-name=SugayaAkiko en-aut-sei=Sugaya en-aut-mei=Akiko kn-aut-name=菅谷明子 kn-aut-sei=菅谷 kn-aut-mei=明子 aut-affil-num=3 ORCID= en-aut-name=NishizakiKazunori en-aut-sei=Nishizaki en-aut-mei=Kazunori kn-aut-name=西﨑和則 kn-aut-sei=西﨑 kn-aut-mei=和則 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　耳鼻咽喉・頭頸部外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　耳鼻咽喉・頭頸部外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　耳鼻咽喉・頭頸部外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　耳鼻咽喉・頭頸部外科学 en-keyword=新生児聴覚スクリーニング検査 kn-keyword=新生児聴覚スクリーニング検査 en-keyword=小児難聴 kn-keyword=小児難聴 en-keyword=補聴器・人工内耳 kn-keyword=補聴器・人工内耳 en-keyword=言語発達 kn-keyword=言語発達 en-keyword=遺伝子診断 kn-keyword=遺伝子診断 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=8 article-no= start-page=1343 end-page=1349 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20068 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Using assessment of higher brain functions of children with GJB2-associated deafness and cochlear implants as a procedure to evaluate language development en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Objective: While investigators have reported that patients with GJB2-associated deafness and cochlear implants have preferable language development, the mechanisms of this phenomenon remains unknown. The goat of the present study was to assess higher brain functions of patients with GJB2-retated and GJB2-unrelated deafness as a method of evaluating language development.
Methods: Eight children with cochlear implants were subjected to genetic testing for GJB2 and underwent the Raven colored progressive matrices test, Rey's auditory verbal learning test, Rey's complex figure test, the standardized Language test for aphasia, the picture vocabulary test, and the standardized comprehension test for abstract words.
Results:Three children were diagnosed with GJB2-related deafness, and five children were diagnosed with GJB2-unrelated deafness. All three GJB2-related cases demonstrated normal range higher brain functions and fair language development. By contrast, one GJB2-unrelated case showed a semantic disorder, another demonstrated a visual cognitive disorder with dyslexia, and another had attention deficit-hyperactivity disorder.
Conclusions:Children with GJB2-unrelated deafness showed a high frequency of heterogeneous disorders that can affect proper language development. This difference between children with GJB2-retated and GJB2-unrelated deafness may account for the improved language development in children with GJB2-related deafness and cochlear implants. Further, genetic diagnosis of the non-syndromic hearing toss represents a useful tool for the preoperative prediction of outcomes following a cochlear implant procedure.

en-copyright= kn-copyright= en-aut-name=KawasakiAkihiro en-aut-sei=Kawasaki en-aut-mei=Akihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukushimaKunihiro en-aut-sei=Fukushima en-aut-mei=Kunihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KataokaYuko en-aut-sei=Kataoka en-aut-mei=Yuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=FukudaShoichiro en-aut-sei=Fukuda en-aut-mei=Shoichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NishizakiKazunori en-aut-sei=Nishizaki en-aut-mei=Kazunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University en-keyword=cochlear implant kn-keyword=cochlear implant en-keyword=higher brain function kn-keyword=higher brain function en-keyword=GJB2 kn-keyword=GJB2 en-keyword=language development kn-keyword=language development en-keyword=non-syndromic hearing loss kn-keyword=non-syndromic hearing loss en-keyword=learninng disability kn-keyword=learninng disability END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=頭頸部非癌組織におけるヒトパピローマウイルス16型DNAのPCR法による検出 kn-title=Human papillomavims field name="type" 16 DNA detected by the polymerase chain reaction in non-cancer tissues of the head and neck en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=福島邦博 kn-aut-sei=福島 kn-aut-mei=邦博 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=3 article-no= start-page=167 end-page=174 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=200106 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Genetic alteration of penicillin non-susceptible Streptococcus pneumoniae observed throughout recurrence of acute otitis media detected by amplified fragment length polymorphism analysis. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The prevalence of penicillin non-susceptible Streptococcus pneumoniae (PNSSP) is increasing among isolates from acute otitis media (AOM). Repeated episodes of antibiotic exposure are a well-known risk factor for the isolation of PNSSP although otitis-prone or recurrent AOM cases frequently require repeated courses of antibiotic treatment. In order to evaluate the chronological alteration of S. pneumoniae during recurrences of AOM, strains of S. pneumoniae were isolated from 11 patients, each of whom had experienced 2-4 episodes of AOM, were examined. Every bacterial specimen obtained from a single episode of recurrent AOM was examined by PCR-based penicillin-binding protein (PBP) assay, serotyping, and amplified fragment length polymorphism (AFLP), then compared to other samples from the same case. Two cases (18.2%) showed strain diversity during repeated antibiotic treatments by serotyping or PBP-assay. By AFLP analysis, 6 cases (54.5%) demonstrated heterogeneous strains during recurrent AOM. Clonal survivors of previous episodes of AOM were not always the cause of subsequent episodes of AOM, even in otitis-prone cases.

en-copyright= kn-copyright= en-aut-name=SugataKen-ichi en-aut-sei=Sugata en-aut-mei=Ken-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukushimaKunihiro en-aut-sei=Fukushima en-aut-mei=Kunihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OgawaTeruhiro en-aut-sei=Ogawa en-aut-mei=Teruhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakashimaTomoko en-aut-sei=Nakashima en-aut-mei=Tomoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SugataAkemi en-aut-sei=Sugata en-aut-mei=Akemi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KasakiNorio en-aut-sei=Kasaki en-aut-mei=Norio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=GunduzMehmet en-aut-sei=Gunduz en-aut-mei=Mehmet kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University affil-num=7 en-affil= kn-affil=Okayama University en-keyword=acute otitis media kn-keyword=acute otitis media en-keyword=amplified fragment length polymorphism(AFLP) kn-keyword=amplified fragment length polymorphism(AFLP) en-keyword=penicillin non-susceptible Streptococcus pncumoniac. kn-keyword=penicillin non-susceptible Streptococcus pncumoniac. END