ID | 32190 |
JaLCDOI | |
FullText URL | |
Author |
Hatano, Atsushi
Uno, Fumio
Nii, Shiro
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Abstract | Ability of two neurovirulent strains (F and +GC (LPV) Miyama) of herpes simplex virus type 1 (HSV-1) to establish and maintain reactivatable latency in trigeminal ganglia (TG) was compared after intranasal inoculation of mice. The +GC (LPV) Miyama strain showed a very low rate of virus reactivation in explant cultures of TG, while the F strain showed a high rate of reactivation. These data indicate that neurovirulent strains of HSV-1 are not always competent for reactivatable latency, although most virulent strains of HSV-1 thus far reported were competent for reactivatable latency.</P> |
Keywords | herpes simplex virus type 1
neurovirulence
latency
reactivation
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Amo Type | Article
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Publication Title |
Acta Medica Okayama
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Published Date | 1991-04
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Volume | volume45
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Issue | issue2
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Publisher | Okayama University Medical School
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Start Page | 117
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End Page | 121
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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File Version | publisher
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Refereed |
True
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PubMed ID | |
Web of Science KeyUT |