Author Sugiura, Yuko| Soga, Yoshihiko| Tanimoto, Ichiro| Kokeguchi, Susumu| Nishide, Sachiko| Kono, Kotoe| Takahashi, Kanayo| Fujii, Nobuharu| Ishimaru, Fumihiko| Tanimoto, Mitsune| Yamabe, Kokoro| Tsutani, Soichiro| Nishimura, Fusanori| Takashiba, Shogo|
Published Date 2008-04
Publication Title Supportive Care in Cancer
Volume volume16
Issue issue4
Content Type Journal Article
Author Murakami, Jun| Asaumi, Jun-ichi| Kawai, Noriko| Tsujigiwa, Hidetsugu| Yanagi, Yoshinobu| Nagatsuka, Hitoshi| Inoue, Tetsuyoshi| Kokeguchi, Susumu| Kawasaki, Shoji| Kuroda, Masahiro| Tanaka, Noriaki| Matsubara, Nagahide| Kishi, Kanji|
Published Date 2005-07
Publication Title Cancer Chemotherapy and Pharmacology
Volume volume56
Issue issue1
Content Type Journal Article
Author Maki, Yu| Murakami, Jun| Asaumi, Jun-ichi| Tsujigiwa, Hidetsugu| Nagatsuka, Hitoshi| Kokeguchi, Susumu| Fukui, Kazuhiro| Kawai, Noriko| Yanagi, Yoshinobu| Kuroda, Masahiro| Tanaka, Noriaki| Matsubara, Nagahide| Kishi, Kanji|
Published Date 2005-7
Publication Title Oral Oncology
Volume volume41
Issue issue10
Content Type Journal Article
Author Okui, Akemi| Soga, Yoshihiko| Kokeguchi, Susumu| Nose, Motoko| Yamanaka, Reiko| Kusano, Nobuchika| Morita, Manabu|
Published Date 2015-07-15
Publication Title Internal Medicine
Volume volume54
Issue issue14
Content Type Journal Article
Author Sugiura, Yuko| Soga, Yoshihiko| Yamabe, Kokoro| Tsutani, Soichiro| Tanimoto, Ichiro| Maeda, Hiroshi| Kokeguchi, Susumu| Fujii, Nobuharu| Ishimaru, Fumihiko| Tanimoto, Mitsune| Nishimura, Fusanori| Takashiba, Shogo|
Published Date 2010-03
Publication Title Supportive Care in Cancer
Volume volume18
Issue issue3
Content Type Journal Article
JaLCDOI 10.18926/AMO/52405
FullText URL 68_2_89.pdf
Author Sako, Shinichi| Kariyama, Reiko| Mitsuhata, Ritsuko| Yamamoto, Masumi| Wada, Koichiro| Ishii, Ayano| Uehara, Shinya| Kokeguchi, Susumu| Kusano, Nobuchika| Kumon, Hiromi|
Abstract We conducted a study on molecular epidemiology and clinical implications of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa isolated from urine. Over a 10-year period from 2001 through 2010, a total of 92 MBL-producing P. aeruginosa urine isolates were collected from patients (one isolate per patient) who were admitted to 5 hospitals in Okayama Prefecture, Japan. When cross-infection was suspected in the hospital, pulsed-field gel electrophoresis was performed. In the resulting dendrogram of 79 MBL-producing P. aeruginosa urine isolates, no identical isolates and 7 pairs of isolates with ≥80% similarity were found. The biofilm-forming capabilities of 92 MBL-producing P. aeruginosa urine isolates were significantly greater than those of 92 non-MBL-producing urine isolates in a medium of modified artificial urine. The imipenem resistance transferred in 16 of 18 isolates tested, and these frequencies were in the range of 10-3 to 10-9. All of 18 isolates tested belonged to internationally spread sequence type 235 and had 3 gene cassettes of antimicrobial resistance genes in the class 1 integron. The strong biofilm-forming capabilities of MBL-producing P. aeruginosa urine isolates could be seriously implicated in nosocomial infections. To prevent spread of the organism and transferable genes, effective strategies to inhibit biofilm formation in medical settings are needed.
Keywords Pseudomonas aeruginosa metallo-β-lactamase molecular epidemiology biofilm urinary tract infection
Amo Type Original Article
Published Date 2014-04
Publication Title Acta Medica Okayama
Volume volume68
Issue issue2
Publisher Okayama University Medical School
Start Page 89
End Page 99
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 24743784
Web of Sience KeyUT 000334652700004
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/52504
Author 苔口 進|
Published Date 1992-03-28
Publication Title
Content Type Thesis or Dissertation