Author 竹田 芳弘|
Published Date 1984-03-31
Publication Title
Content Type Thesis or Dissertation
JaLCDOI 10.18926/AMO/48077
FullText URL 66_1_17.pdf
Author Hayashida, Keiichi| Takeda, Yoshihiro| Katsuda, Toshizo| Yamamoto, Kenyu| Suesada, Yasuhide| Shibata, Moeko| Azuma, Masami|
Abstract Proximal femoral bone mineral density (BMD) can be measured by dual energy X-ray absorptiometry method in the neck, trochanter, intertrochanter, total and Ward's triangle area. Ward's triangle area of the proximal femur is a smaller area to measure than the others, and the position varies, depending on the status of inner rotation of the target leg. In this study, the measurements of the proximal femoral BMD in women were carried out on the neck, trochanter, intertrochanter, total and Ward's triangle area with the, subjects' legs turned 15 degrees toward the inside. The Ward's BMD were measured using Ward's cognitive method, in which the measured BMD were compared among age groups of 50-59, 60-69, 70-79 and 80-89 to determine whether this process could reveal decreased femoral BMD in elderly women. The correlation between BMD and age was tested using the Pearson correlation coefficient. In all measured parts, the BMD of women age 50-59 were significantly higher than those of women age 80-89. The correlations between BMD and age were negative in all measured parts, and the most negative correlation was between age and Ward's BMD. The study using Ward's cognitive method showed an inverse correlation between Ward's BMD and age in women.
Keywords proximal femoral BMD dual energy X-ray absorptiometry Wardʼs BMD Wardʼs cognitive method
Amo Type Original Article
Published Date 2012-02
Publication Title Acta Medica Okayama
Volume volume66
Issue issue1
Publisher Okayama University Medical School
Start Page 17
End Page 21
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22358135
Web of Science KeyUT 000300800700003
JaLCDOI 10.18926/11690
Title Alternative A study of x-rays protection in a hip-joint radiography examination
FullText URL 011_2_059_064.pdf
Author Nakagiri, Yoshitada| Maruyama, Toshinori| Goto, Sachiko| Azuma, Yoshiharu| Shibuya, Koichi| Tamura, Eri| Tanimoto, Eriko| Torii, Fumiko| Takeda, Yoshihiro| Sugita, Katsuhiko|
Abstract 幼小児を含めた若年者の股関節X線撮影検査においては鉛板などで生殖腺を防護して行うのが通常である。男性の場合は生殖腺は体外に露出しているので,それを鉛板で包むようにすればある程度目的は達成される。しかし,女性の場合,生殖腺は骨盤腔内に存在するため,卵巣及び子宮を防護でき診断目的領域にかからないように鉛板を成形し,腹壁上に置いて撮影する。X斬写真上ではグリッドで散乱線を除去しているため,鉛板の陰影がくっきりと撮影され,生殖腺は完全に防護されているように見える。しかし,体内では散乱線によるかなりの被曝があるものと考えられる。そこで今回,鉛板下の散乱線量を鉛板幅及び電圧を変化させ,ファントム内各深さの散乱線量を測定した。その結果,鉛板下の散乱線量が相当量認められ,その量は深さ3~4cmでピークを形成した。鉛板幅による変化は幅が狭いほど線量は大きくなり,電圧による変化は60kVと80kVを比べると80kVの方が多くなった。これを鉛板なしの場合と比較すると,ファントム内意さが増すにしたがい増大した。したがって,臨床において鉛板がずれて再撮影をすることのないよう細心の注意が必要であると考えられた。
Abstract Alternative Usually in a hip-joint radiographic examination for the youth including children, the gonads should be well protected with an appropriate lead shield etc. Since the male gonads are in the outside of the body, if covered with a lead shield, the shield can protect them. However, in the case of the female, since the gonads of exist in a pelvic cavity, the lead shield is cut to a specific pattern so that it can protect the ovaries and the womb, and it is set on the abdomen during the radiographic exposure. Since the scattered radiation on an X-ray film can be removed with the grid, the image of a lead shield is obtained clearly, and the gonads seem to be protected completely. The shield can not protect the gonads of the female from the scattered radiation, though it protects them almost completely from the primary X-rays beam. Therefore, the gonads have radioactive contamination from scattered radiation. Then, in order to estimate the amount of scattered radiation under the lead shield, the dose under the shield was measured by using a phantom in this research, changing lead shield width, the tube-voltage, and the monitoring depth of a phantom. As a results, the dose under the lead shield was observed considerably and showed the peak at the depth of 3 or 4cm. Therefore, it was thought that a careful caution was required for obviating lead shield in clinical.
Keywords 股関節X線撮影 (Radiography Examination of Hip-joint) 医療被爆 (Patient Dose) X線測定 (Dosimetry) 生殖腺防護 (X-rays Protection of the Gonads)
Publication Title 岡山大学医学部保健学科紀要
Published Date 2001-03-24
Volume volume11
Issue issue2
Start Page 59
End Page 64
ISSN 1345-0948
language 日本語
File Version publisher
NAID 120002313720
JaLCDOI 10.18926/11714
Title Alternative スクリーン/フィルム乳房撮影法における乳房線量測定システム
FullText URL 010_2_099_106.pdf
Author Goto, Sachiko| Azuma, Yoshiharu| Maruyama, Toshinori| Nakagiri, Yoshitada| Takeda, Yoshihiro| Sugita, Katsuhiko| Kadohisa, Shigefumi|
Abstract The average glandular dose to glandular tissue m mammography is generally assumed to be a function of beam quality (HVL), x-ray tube target material, tube voltage, breast thickness, breast composition and, to a lesser extent, x-ray tube voltage waveform. The average glandular dose is generally determined from published tables with knowledge of the above function. Tables for a high frequency x-ray generator are not yet published. In our study, the lookup tables for the average glandular dose were made at 28 kV (high frequency x-ray generator), employing a breast simulating tissue (0-100% adipose tissue, 0-100% glandular tissue) phantom for an Mo target - Mo filter source assembly. We tried to estimate breast composition from x-ray mammograms by digital image processing techniques, also using the simulating tissue phantom. Then the system that automatically calculates the average glandular dose from digitized clinical x-ray mammograms was built. It is considered that this system can contribute to objective evaluation of the average glandular dose.
Abstract Alternative 乳房X線撮影法において乳腺組織に対する平均放射線吸収線量,すなわち平均乳腺線量は放射線のリスクの最も有用な測定法であり,現在,乳房に対する線量の評価に用いられている指標である。一般に,平均乳腺線量は線質(HVL),X線管球ターゲット材料,管電圧,圧迫乳房厚さ,乳房構成および(ある程度)X線管電圧波形の関数であるとされている。平均乳腺線量は,上記の関数についての情報を備えた表が公表されており,一般にその表を使って決定されている。近年,インバータ式といわれる高周波X線発生装置が普及してきた。しかし,その装置用の表は,まだ公表されていない。我々の研究では,乳房組織をシュミレートするファントム(0~100%乳腺組織,0~100%脂肪組織)を使用して,28kVでMoターゲット―Moフィルタソースアセンブリーを備えた高周波X線発生装置のために,平均乳腺線量用のルックアップテーブルを作成した。同様に,乳房組織をシュミレートするファントムを使用して,乳房X線写真から,ディジタル・イメージプロセシング技術によって,乳房構成の評価を試みた。そして,ディジタイズされた臨床乳房X線写真から,平均乳腺線量を自動的に計算するシステムを構築した。サンプル数が少ないため断定はできないが,日本女性は,基準構成(50%の脂肪および50%の乳腺組織)と比較すると,脂肪が少ない傾向を分析結果は示唆していた。また,平均乳腺吸収線量の限度は,明確に規定されていないが,American College of Radiology(ACR)は4 mGyなどを推奨している。また日本では,3 mGyが推奨されているが,我々の撮影システムはこれらを十分満足していた。このように本システムは,平均乳腺線量の客観的な評価に寄与するとともに,DR(digital radiography)などに応用すると,すなわちルックアップテーブルをDRのコンピュータに保存しておけば,撮影後すぐに乳房構成および平均乳腺線量を算出できる可能性をもつ。
Keywords Screen/Film Mammography (スクリーン/フィルム乳房撮影法) Breast composition (乳房構成) Average glandular dose (平均乳腺線量) Entrance skin exposure (皮膚入射線量) Breast-equivalent material phantom (乳房組織等価ファントム)
Publication Title 岡山大学医学部保健学科紀要
Published Date 2000-03-24
Volume volume10
Issue issue2
Start Page 99
End Page 106
ISSN 1345-0948
language 英語
File Version publisher
NAID 120002313736
JaLCDOI 10.18926/11730
Title Alternative Measurement of intracellular pH by flow cytometry using pH sensitive fluorescence dye, and influence of hyperthermia and amiloride derivatives on the intracellular pH
FullText URL 006_001_005.pdf
Author Asaumi, Jun-ichi| Kawasaki, Shoji| Kuroda, Masahiro| Takeda, Yoshihiro| Hiraki, Yoshio|
Abstract エールリッヒ腹水癌細胞とそのアドリアマイシン耐性細胞において蛍光pH指示薬2'、7'-bis-(2-carboxyethyl) carboxyfluorescein] (BCECF) の蛍光量をフローサイトメトリーで測定することによって細胞内pHの検量曲線を作成することができた。このことより、これらの細胞においてBCECFの蛍光量で細胞内pHの変化を簡易に比較できることを示唆した。さらに、温熱、Na(+)/H(+) exchanger の阻害例であるアミロライド[3,5-diamino-6-chloro-N-(diaminomethylene) pyrazinecarboxamide]、およびアミロライド誘導隊MH-12-43[N-amidino-3-amino-6-chloro-5-(N-ethyliso-propylamino) pyrazinecarboxyamide] の細胞内pHへの影響をエールリッヒ腹水癌細胞で観察した。37℃では、0.5mMアミロライド、0.05mM MH-12-43により細胞内pHは減少し、42℃処理によりさらに減少した。42℃において、0.05mM MH-12-43による細胞内pHの減少は、0.5mMアミロライドによる減少より大きかった。
Abstract Alternative We examined relationship between intensity of intracellular fluorescence of [2', 7'-bis-(2'-carboxyethyl) carboxyfluorescein] (BCECF) and intracellular pH in Ehrlich ascites tumor cells and their adriamycin-resistant strain, and found a good correlation between them at both strains. This suggests that changes in the intracellular pH on these strains may be obtained through measurement of intracellular fluorescence of BCECF by flow cytometry. Further, we examined influence of hyperthermia, 3, 5-diamino-6-chloro-N-(diaminomethylene)pyrazinecarboxamide (amiloride), an inhibitor of Na(+)/H(+) exchanger, and its derivative; N-amidino-3-amino-6-chloro-5-(N-ethylisopropylamino) pyrazinecarboxyamide (MH-12-43) on the intracellular pH in Ehrlich ascites tumor cells. The treatment of 0.5mM amiloride or 0.05mM MH-12-43 reduced intracellular pH at 37℃, while the more reduction was observed by the treatment at 42℃. The reduction of intracellular pH by 0.05mM MH-12-43 was more substantial than that of 0.5mM amiloride at 42℃.
Keywords BCECF 細胞内pH (Intracellular pH) フローサイトメトリー (Flow Cytometry) アミロライド (Amiloride) MH-12-43
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1996-02-29
Volume volume6
Start Page 1
End Page 5
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313855
JaLCDOI 10.18926/11735
Title Alternative Clinical application of the contrast media containing soft drinks for the X-ray examination of the stomach
FullText URL 006_015_021.pdf
Author Shibuya, Koichi| Nakagiri, Yoshitada| Azuma, Yoshiharu| Goto, Sachiko| Maruyama, Toshinori| Sugita, Katsuhiko| Okura, Yasuhiko| Natsukawa, Koichi| Tandani, Nobuyoshi| Nobuhara, Eitaro| Morioka, Yasuki| Takeda, Yoshihiro| Hiraki, Yoshio|
Abstract 胃X線検査の被験者を増やし、検査を円滑に行う上で造影剤である硫酸バリウム懸濁液の飲みにくさが障害の一つとなっている。これを改善する目的で、懸濁液に市販の粉末清涼飲料を混入したところ、64.2%の人が通常のものよりも飲みやすいと答えた。臨床上も造影剤の付着が悪くなったり、胃の蠕動を促進する等の問題は生じず、有用であると考えられた。
Abstract Alternative Barium sulfate suspensions are disliked by many people. This is one of the obstacles to increase persons who consult doctors and to have medical examinations smoothly. We mixed soft drinks into the suspensions to improve this problem. As a result, they were popular among 64.2% people, there were not any clinical troubles that the suspensions did not stick to the mucous membrane of the stomach well, the peristalsis of the sotmach were promoted, and so on. These results suggest that the contrast media containing soft drinks is useful for the X-ray examinations of the stomach.
Keywords 造影剤 (contrast media) 硫酸バリウム (barium sulfate suspension) 清涼飲料 (soft drinks) 消化管検査 (barium examination)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1996-02-29
Volume volume6
Start Page 15
End Page 21
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002313345
FullText URL NMC40_7_703.pdf
Author Nakashima, Masahiro| Shinya, Takayoshi| Oto, Takahiro| Okawa, Tomoyo| Takeda, Yoshihiro|
Keywords bronchiolitis obliterans syndrome forced expiratory volume function volume lung transplantation morphological volume
Note This is a accepted manuscript of Nakashima, Masahiro et. al. Diagnostic value of ventilation/perfusion single-photon emission computed tomography/computed tomography for bronchiolitis obliterans syndrome in patients after lung transplantation. Nuclear Medicine Communications. (2019) 40(7), 703-710. To see pulished version, see doi: 10.1097/MNM.0000000000001021.|
Published Date 2019-07
Publication Title Nuclear Medicine Communications
Volume volume40
Issue issue7
Publisher Lippincott, Williams & Wilkins
Start Page 703
End Page 710
ISSN 0143-3636
NCID AA10624879
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 31022070
DOI 10.1097/MNM.0000000000001021
Web of Science KeyUT 000472672100006
Related Url isVersionOf https://doi.org/10.1097/MNM.0000000000001021
JaLCDOI 10.18926/15252
Title Alternative Extended-cycle processによる乳房撮影用増感紙/フィルムシステムの画質改善
FullText URL 009_2_083_090.pdf
Author Goto, Sachiko| Maruyama, Toshinori| Azuma, Yoshiharu| Nakagiri, Yoshitada| Takeda, Yoshihiro| Sugita, Katsuhiko| Kimura, Fumie| Kadohisa, Shigefumi|
Abstract Extended-cycle process is the term used for a processor in which the processing time has been prolonged usually to approximate 210 seconds. It has been known that the extended-cycle process of some single-emulsion films as used for mammography may enhance film contrast and increase film speed. So the speed was increased in lower speed and higher resolution system than conventional systems by means of using the extended-cycle process in this paper. We investigated how much the resolution of the system was kept. A single screen-single emulsion combination, Konica M-100/CM-H was employed as a low speed and high resolution system. This film after exposure was processed in the different combinations of developing temperatures, 30, 32 and 34℃, and processing time of 210 seconds. On the other hand, Konica M-200/CM-H was employed as a high speed system. This film was processed in the standard-cycle processing (34℃, 90 seconds). Those systems were compared on contrast, speed, screen-film blur and noise by a characteristic curve, MTF (modulation transfer function) and WS (wiener spectrum). Furthermore, the RMI 165 phantom was used to evaluate visibility of mammographic details of these systems. As a result, in the extended-cycle process at the developing temperatures of 32 or 34°C and processing time of 210 seconds for M-100/CM-H, it was possible to increase the speed as much as the higher speed system, M-200/CM-H. Then the contrast, the MTF and the visibility were also improved as compared to the higher speed system. Furthermore patient dose could be reduced at the developing temperature of 34℃ and processing time of 210 seconds in M-100/CM-H.
Abstract Alternative 通常,extended-cycle processは処理時間が約210秒に延ばされた現像機のために使われる用語である。乳房撮影に使われるような片面乳剤フィルムにおけるextended-cycle processは,フィルムコントラストを増し,感度をあげることが良く知られている。そこで,本論文ではextended-cycle processにより低感度,高解像度システムの感度を上げ,どの程度解像度が維持されるかを調べた。片面増感紙/片面フィルムの組合わせであるKonica M-100/CM-Hを低感度,高解像度システムとして用いた。露光後のフィルムは現像温度30,32, 34度,処理時間210秒の異なる組合わせで現像処理した。一方,高感度システムとしてKonica M-200/CM-Hを用い,このフィルムは標準現像(34℃,90秒)された。感度,増感紙/フイルムのぼけ,雑音に関して,特性曲線,MTF(modulation transfer function), WS(wiener spectrum)によってこれらのシステムを比較した。さらにこれらのシステムにおける乳房写真の細部視覚評価のためにRM165ファントムを使用した。その結果,M-100/CM-Hに対するextended-cycle process現像温度32, 34℃,処理時間210秒のextended-cycle processにおいて,高感度システムM-200/CM-Hと同等の感度を上げることが可能であった。そのとき,コントラスト,MTF,視覚的検出能も高感度システムより向上した。さらに,現像温度34℃,処理時間210秒では,被曝線量の低減が可能であった。
Keywords image quality mammography single screen-single emulsion film system high-resolution screen extended-cycle process
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1999-02-26
Volume volume9
Issue issue2
Start Page 83
End Page 90
ISSN 0917-4494
language 英語
File Version publisher
NAID 120002307881
JaLCDOI 10.18926/15274
Title Alternative Clinical evaluation of barium sulfate suspensions "Barytgen HD" - Second report -
FullText URL 009_1_041_048.pdf
Author Nobuhara, Eitarou| Takeda, Yoshihiro| Niiya, Harutaka| Shibuya, Koichi| Morioka, Yasuki| Nakagiri, Yoshitada| Joja, Ikuo| Sugita, Katsuhiko| Hiraki, Yoshio|
Abstract 混合粒子型硫酸バリウム「バリトゲンHD」の懸濁液最適濃度について,検討を行った。懸濁液安定性は,200w/v%と190w/v%は良好であったが,180w/v%は不良で臨床使用には不向きであると思われた。臨床的評価において200w/v%と190w/v%は付着性,辺縁の描出能,胃小区描出能においては同程度であった。200w/v%に多く見られた凝集・ムラ付き,気泡は,190w/v%では少なくなった。飲み易さは,200w/v%,190w/v%とも飲み易いと評価されたが,190w/v%でより飲み易い傾向にあった。バリトゲンHDの最適懸濁液濃度は,190w/v%であると思われる。
Abstract Alternative Barium sulfate suspensions in 200w/v% and 190w/v% had good stability. But in 180w/v% it had worse stability. Significant difference was not observed in coating, visualization of gastric margin and gastric area between in 200w/v% and 190w/v%. Barium sulfate suspensions in 190w/v% had less sticky coating of gastric mucosa and fewer bubbles than 200w/v%. Barium sulfate suspensions in 190w/v% was easiest density to drink. 190w/v% seems to be most adequate density in our study.
Keywords 造影剤 (contrast medium) 硫酸バリウム (barium sulfate suspension) 消化管検査 (barium examination)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1998-09-30
Volume volume9
Issue issue1
Start Page 41
End Page 48
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002307256
JaLCDOI 10.18926/15290
Title Alternative Clinical evaluation was examined between mixed type barium sulfate suspensions "BarytgenHD" and "Barytgen"
FullText URL 007_2_105_112.pdf
Author Nobuhara, Eitarou| Takeda, Yoshihiro| Shibuya, Kohichi| Oguri, Nobuhiro| Arioka, Tadashi| Goto, Sachiko| Morioka, Yasuki| Niiya, Harutaka| Nakagiri, Yoshitada| Joja, Ikuo| Sugita, Katsuhiko| Hiraki, Yoshio|
Abstract 混合粒子型硫酸バリウムバリトゲンHD200w/v%懸濁液について,バリトゲン160w/v%懸濁液と比較検討を行った。懸濁液安定性は両者共良かった。臨床評価においては,付着性,胃小区描出能は同程度であり,辺縁の描出能は良かったが凝集・ムラ付き,気泡は多くみられ懸濁液濃度について検討を加える必要があると考える。飲み易さは,バリトゲンHD200w/v%懸濁液のほうが濃度が高いのにもかかわらず飲み易く好評であった。
Abstract Alternative Both barium sulfate suspensions, Barytgen HD and Barytgen, had good stability. Although significant difference was not abserved in coating and visualization of gastric area, BarytgenHD showed better marginal visualization of gastric margin. Further study is needed to improve the visualization of sticky coating of gastric mucosa and many bubbles. BarytgenHD was easily to drink instead of high density barium sulfate suspensions.
Keywords 造影剤 (contorast media) 硫酸バリウム (barium sulfate suspension) 消化管検査 (barium examination)
Publication Title 岡山大学医療技術短期大学部紀要
Published Date 1997-01-31
Volume volume7
Issue issue2
Start Page 105
End Page 112
ISSN 0917-4494
language 日本語
File Version publisher
NAID 120002307979
JaLCDOI 10.18926/AMO/31118
FullText URL fulltext.pdf
Author Tsunoda, Masatoshi| Kimoto, Shin| Hamazaki, Keisuke| Takeda, Yoshihiro| Hiraki, Yoshio|
Abstract <p>A non-invasive method for measuring portal blood flow by magnetic resonance (MR) phase contrast was evaluated in a flow phantom and 20 healthy volunteers. In a flow phantom study, the flow volumes and mean flow velocities measured by MR phase contrast showed close correlations with those measured by electromagnetic flowmetry. In 20 healthy volunteers, the cross-sectional areas, flow volumes and mean flow velocities measured by MR phase contrast correlated well with those measured by the Doppler ultrasound method. Portal blood flow averaged during the imaging time could be measured under natural breathing conditions by using a large number of acquisitions without the limitations imposed on the Doppler ultrasound method. MR phase contrast is considered to be useful for the non-invasive measurement of portal blood flow.</p>
Keywords portal blood flow magnetic resonance imaging phase contrast
Amo Type Article
Published Date 1994-10
Publication Title Acta Medica Okayama
Volume volume48
Issue issue5
Publisher Okayama University Medical School
Start Page 283
End Page 288
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7863800
Web of Science KeyUT A1994PP23600009
JaLCDOI 10.18926/AMO/31557
FullText URL fulltext.pdf
Author Kuroda, Masahiro| Hizuta, Akio| Iwagaki, Hiromi| Makihata, Eiichi| Asaumi, Junichi| Nishikawa, Koji| Gao, Xian Shu| Nakagawa, Tomio| Togami, Izumi| Takeda, Yoshihiro| Joja, Ikuo| Kawasaki, Shoji| Orita, Kunzo| Hiraki, Yoshio|
Abstract <p>Between November 1984 and August 1992 we used hyperthermotherapy in six cases of local recurrence of rectal cancer. Hyperthermotherapy was performed on the average 8.7 times (range: 3-18) for each patient for 60 min each. All patients underwent combined radiotherapy and received a mean radiation dose of 42.5 Gy (range: 9-60 Gy). Five patients underwent heating within 1 h after irradiation and one patient simultaneously with the irradiation. Four patients underwent combined chemotherapy and two patients immunotherapy. Before the treatment all patients had painful lesions, but pain decreased posttherapeutically in five patients. Performance status improved in two patients. High carcinoembryonic antigen levels prior to the therapy in four patients decreased in all cases after treatment. Posttherapeutical computed tomograms revealed only minor response or no changes. After the treatment, four patients died of exacerbations of recurrent tumors and one patient of distant metastases. The patient who underwent simultaneous radiohyperthermotherapy is presently alive, in August 1992, 38 months after initiation of the treatment. The 50% survival time after initiation of the treatment was 25 months (range: 10-38 months). Hyperthermotherapy combined with radiotherapy, chemotherapy and/or immunotherapy was useful for the alleviation of pain in patients who developed local recurrence after surgery, and improved survival after recurrences can be expected.</p>
Keywords rectal cancer local recurrence hyperthermia radiotherapy chemotherapy
Amo Type Article
Published Date 1993-08
Publication Title Acta Medica Okayama
Volume volume47
Issue issue4
Publisher Okayama University Medical School
Start Page 249
End Page 254
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8213219
Web of Science KeyUT A1993LV73800005
JaLCDOI 10.18926/AMO/31576
FullText URL fulltext.pdf
Author Fujishima, Mamoru| Suemitsu, Ichizou| Sei, Tetsurou| Takeda, Yoshihiro| Hiraki, Yoshio|
Abstract <p>A total of 124 lesions from 1 to 6cm in diameter, including 31 cavernous hemangiomas, 32 metastases and 61 hepatocellular carcinomas (HCC) were analyzed to study the usefulness of magnetic resonance imaging (MRI) at 0.5 Tesla to differentiate focal hepatic lesions on the basis of qualitative criteria. Each focal hepatic lesion was assessed for shape, internal architecture and signal intensity relative to normal liver parenchyma. While all cavernous hemangiomas and metastases except one lesion could be detected, detection rate of HCC was significantly inferior to that of the other two diseases. A tumor capsule and a hyperintense focus on T1-weighted images were demonstrated in only HCC lesions in strong contrast with the other two diseases; however, metastases with slow-growing characteristics or subacute hematoma may appear as similar images. Cavernous hemangiomas appeared markedly hyperintense on T2-weighted images in 23 of 31 lesions, but one metastasis and one HCC had similar images. A multivariate analysis of several MRI resulted in the following mean discriminant scores: cavernous hemangioma, -1.2652; metastasis, 0.1830; and HCC, 0.7138. It appeared to be possible to differentiate the three diseases with 84.4 percent accuracy.</p>
Keywords magnetic resonance imaging liver neoplasms multivariate analysis
Amo Type Article
Published Date 1993-04
Publication Title Acta Medica Okayama
Volume volume47
Issue issue2
Publisher Okayama University Medical School
Start Page 117
End Page 120
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8389524
Web of Science KeyUT A1993LA45200008
JaLCDOI 10.18926/AMO/31599
FullText URL fulltext.pdf
Author Kuroda, Masahiro| Tsushima, Tomoyasu| Nasu, Yasutomo| Asaumi, Junichi| Nishikawa, Koji| Gao, Xian Shu| Joja, Ikuo| Takeda, Yoshihiro| Togami, Izumi| Makihata, Eiichi| Kawasaki, Shoji| Ohmori, Hiroyuki| Hiraki, Yoshio|
Abstract <p>We performed a long-term follow-up of 4 patients with penile cancer who underwent hyperthermotherapy from August 1985 until August 1992. Hyperthermia was applied using a frequency of 350 MHz with a waveguide applicator twice a week for 60 min each for an average of 9.5 times (varying from 6 to 13 times). The total heating time that the temperature of urethra could be kept above 42 degrees C, was 166 min on the average (ranging from 0 to 463 min). Two patients classified as stage I according to the Jackson classification and 1 patient classified as stage IV underwent combined radiotherapy and received an average radiation dose of 53 Gy (range, 40-70 Gy). Among these patients 2 underwent combined chemotherapy with bleomycin or peplomycin. Malignant cells disappeared posttherapeutically and in August 1992, after an average of 5 years and 9 months (varying from 4 years 6 months to 6 years 10 months), the patients were free of recurrences. The one patient on stage IV had extensive invasion of the abdominal wall, but still recovered completely. One patient on stage III underwent combined chemotherapy and hyperthermotherapy, but heating had obviously been insufficient. There was a residue of malignant cells after the treatment and we performed a penectomy. Regarding functional preservation of the penis a multidisciplinary therapy incorporating hyperthermotherapy can be expected to increase the curativity. This indicates that it could induce in an advanced case, where an operation would be difficult, complete remission.</p>
Keywords penile cancer hyperthermia radiotherapy chemotherapy
Amo Type Article
Published Date 1993-06
Publication Title Acta Medica Okayama
Volume volume47
Issue issue3
Publisher Okayama University Medical School
Start Page 169
End Page 174
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8379345
Web of Science KeyUT A1993LL12400005
JaLCDOI 10.18926/AMO/31634
FullText URL fulltext.pdf
Author Suzuki, Yasunori| Kohno, Yoshihiro| Takeda, Yoshihiro| Hiraki, Yoshio|
Abstract <p>To investigate the correlation between nuclear medicine parameters determined by technetium-99m-DTPA-galactosyl-human serum albumin (Tc-99m-GSA) and liver function tests, canonical correlation analysis was performed. Tc-99m-GSA studies were performed on 47 patients with hepatocellular carcinoma (HCC) who had undergone transcatheter arterial embolization (TAE). The nuclear medicine parameters LU15, HH15 and LHL15, which are results of nuclear imaging tests, were chosen in combination with the following liver function tests: the serum bilirubin level (T.Bil), the serum albumin level (Alb), serum cholinesterase activity (Ch-E), the clearance rate of indocyanine green (KICG), the hepaplastin test (HPT) and the prothrombin time (PT). The canonical correlation coefficient was 0.7345 and the upper tail probability was 0.00167. A significant correlation was observed between the two sets of variables. The high structural coefficients of Ch-E, KICG and HPT indicated a close relationship with the nuclear medicine parameters, supporting the notion that these nuclear medicine parameters are useful for the estimation of liver damage. The structural coefficients of the nuclear medicine parameters were also high, with LU15 being a parameter as useful as both HH15 and LHL15. T.Bil may evaluate a liver function that is not measured by nuclear imaging techniques, so we should take T.Bil results into account before considering TAE.</p>
Keywords Technetium-99m-DTPA-galactosyl-human serum albumin hepatocellular carcinoma transcatheter arterial embolization multivariate analysis
Amo Type Article
Published Date 1999-10
Publication Title Acta Medica Okayama
Volume volume53
Issue issue5
Publisher Okayama University Medical School
Start Page 225
End Page 232
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 10561731
Web of Science KeyUT 000083427100004
JaLCDOI 10.18926/AMO/32098
FullText URL fulltext.pdf
Author Yamamoto, Yasuhiro| Okumura, Yoshihiro| Sato, Shuhei| Maki, Kumi| Mukai, Takashi| Mifune, Hirofumi| Akaki, Shiro| Takeda, Yoshihiro| Kanazawa, Susumu| Hiraki, Yoshio|
Abstract <p>We studied the differentiation of thyroid nodules using fine-needle aspiration biopsy (FNA) and Tl-201 scintigraphy quantitative analysis. One-hundred and thirty-one thyroid nodules were examined: 83 follicular lesions (58 benign and 25 malignant lesions) and 48 non-follicular lesions (8 benign and 40 malignant lesions). During Tl-201 scintigraphy examinations, an early and a delayed image were acquired 10 and 120 min after an intravenous injection, respectively. The T/N ratio (counts of nodular lesion/counts of contralateral normal thyroid tissue) of each image was calculated quantitatively. We assessed the ability of the Tl-201 scintigraphy and of the FNA analysis to differentiate benign and malignant lesions and determined the cut-off levels for the assays. For the follicular lesions, the area under the ROC (Receiver Operating Characteristic) curve (Az) for the Tl-201 scintigraphy data was greater than that for the FNA data. For the non-follicular lesions, the Az for the FNA data was greater than that for the Tl-201 scintigraphy data. We set cut-off levels at 1.370 for follicular lesions, and 1.070 for non-follicular lesions. The sensitivity and specificity were 76% and 82.7% for follicular lesions, and 90% and 87.5% for non-follicular lesions, respectively. The overall accuracy of the analysis was 84.0%.</p>
Keywords ?thyroid nodules fine-needle aspiration biopsy(FNA) Tl-201scintigraphy
Amo Type Article
Published Date 2004-04
Publication Title Acta Medica Okayama
Volume volume58
Issue issue2
Publisher Okayama University Medical School
Start Page 75
End Page 83
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 15255508
Web of Science KeyUT 000221043700003
JaLCDOI 10.18926/AMO/32116
FullText URL fulltext.pdf
Author Kurose, Taichi| Okumura, Yoshihiro| Sato, Shuhei| Yamamoto, Yasuhiro| Akaki, Shiro| Takeda, Yoshihiro| Kanazawa, Susumu| Ando, Akio| Date, Hiroshi| Shimizu, Nobuyoshi| Hiraki, Yoshio|
Abstract <p>We evaluated the respiratory functions of patients with pulmonary emphysema who underwent lung volume reduction surgery (LVRS) by the mean transit time (MTT) with Xe-133 lung ventilation scintigraphy, forced expiration volume in 1 sec (FEV1.0), residual volume (RV), distance walked in 6 min (6-min walk), and the Hugh-Jones classification (H-J classification) before and after LVRS. In 69 patients with pulmonary emphysema (62 men, 7 women; age range, 47-75 years; mean age, 65.4 years +/- 6.1, preoperative H-J classification, III (two were II)-V) who underwent LVRS, all preoperative and postoperative parameters (MTT 3 weeks after LVRS and the others 3 months after LVRS) were judged statistically by the Wilcoxon signed-ranks test and Odds ratio. Every postoperative parameter was improved with a significant difference (P &#60; 0.05) compared to preoperative parameters. MTT at 3 weeks after LVRS was not associated with %FEV1.0 and the H-J classification at 3 months after LVRS, but was associated with RV and a 6-min walk at 3 months after LVRS. MTT was useful for the clinical evalution of aerobic capability after LVRS.</p>
Keywords lung volume reduction surgery (LVRS) respiratory functions Xe-133 lung ventilation scintigraphy pulmonary emphysema
Amo Type Article
Published Date 2004-02
Publication Title Acta Medica Okayama
Volume volume58
Issue issue1
Publisher Okayama University Medical School
Start Page 7
End Page 15
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 15157006
Web of Science KeyUT 000189271100002
FullText URL BreastCancer_24_4_593.pdf BreastCancer_24_4_593_tbl_fig.pdf
Author Yatake, Hidetoshi| Sawai, Yuka| Nishi, Toshio| Nakano, Yoshiaki| Nishimae, Ayaka| Katsuda, Toshizo| Yabunaka, Koichi| Takeda, Yoshihiro| Inaji, Hideo|
Keywords Breast cancer Direct methods Mammography Mask methods Stereotactic vacuum assisted biopsy
Published Date 2017-07
Publication Title Breast Cancer
Volume volume24
Issue issue4
Publisher Japanese Breast Cancer Society
Start Page 593
End Page 600
ISSN 1340-6868
NCID AA1103354X
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 27878446
DOI 10.1007/s12282-016-0743-y
Web of Science KeyUT 000404221100015
Related Url https://doi.org/10.1007/s12282-016-0743-y
Author Hayashi, Hidehiro| Hiraki, Yoshio| Joja, Ikuo| Kashitani, Naoko| Miyake, Masayoshi| Yamamoto, Yoshio| Kanzaki, Noriko| Inoue, Nobuhiro| Noriyasu, Toshiaki| Hashimoto, Keiji| Takeda, Yoshihiro| Mizuta, Akihumi| Sugita, Katsuhiko| Aono, Kaname|
Published Date 1987-02-28
Publication Title 岡山医学会雑誌
Volume volume99
Issue issue1-2
Content Type Journal Article
Author Noriyasu, Toshiaki| Hiraki, Yoshio| Takeda, Yoshihiro| Mimura, Hidehumi| Mitani, Masahiko| Nagayama, Masako| Kimoto, Shin| Kaji, Mitsumasa| Hashimoto, Keiji| Aono, Kaname|
Published Date 1988
Publication Title 岡山医学会雑誌
Volume volume100
Issue issue9-10
Content Type Journal Article