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Author Yumoto, Tetsuya| Naitou, Hiromichi| Ihoriya, Hiromi| Yorifuji, Takashi| Nakao, Atsunori|
Published Date 2019-01-29
Publication Title PLoS ONE
Volume volume14
Issue issue1
Publisher Public Library of Science
Start Page e0207049
ISSN 1932-6203
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2019 Yumoto et al.
File Version publisher
PubMed ID 30695039
DOI 10.1371/journal.pone.0207049
Web of Science KeyUT 000457046400004
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0207049
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Author Yumoto, Tetsuya| Naitou, Hiromichi| Yorifuji, Takashi| Aokage, Toshiyuki| Fujisaki, Noritomo| Nakao, Atsunori|
Keywords Glasgow coma scale Japan Coma Scale Mortality Trauma Traumatic brain injury
Published Date 2019-11-06
Publication Title BMC Emergency Medicine
Volume volume19
Issue issue1
Publisher BMC
Start Page 65
ISSN 1471-227X
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2019
File Version publisher
PubMed ID 31694575
DOI 10.1186/s12873-019-0282-x
Web of Science KeyUT 000495573700001
Related Url isVersionOf https://doi.org/10.1186/s12873-019-0282-x
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Author Yumoto, Tetsuya| Naitou, Hiromichi| Yorifuji, Takashi| Tahara, Yoshio| Yonemoto, Naohiro| Nonogi, Hiroshi| Nagao, Ken| Ikeda, Takanori| Sato, Naoki| Tsutsui, Hiroyuki|
Keywords out-of-hospital cardiac arrest outcome national meeting cardiopulmonary resuscitation
Published Date 2019-12-16
Publication Title International Journal of Environmental Research and Public Health
Volume volume16
Issue issue24
Publisher MDPI
Start Page 5130
ISSN 1661-7827
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2019 by the authors.
File Version publisher
PubMed ID 31888125
DOI 10.3390/ijerph16245130
Web of Science KeyUT 000507312700245
Related Url isVersionOf https://doi.org/10.3390/ijerph16245130
JaLCDOI 10.18926/AMO/55433
FullText URL 71_5_363.pdf
Author Yumoto, Tetsuya| Kosaki, Yoshinori| Yamakawa, Yasuaki| Iida, Atsuyoshi| Yamamoto, Hirotsugu| Yamada, Taihei| Tsukahara, Kohei| Naito, Hiromichi| Osako, Takaaki| Nakao, Atsunori|
Abstract Worldwide, hemorrhagic shock in major trauma remains a major potentially preventable cause of death. Controlling bleeding and subsequent coagulopathy is a big challenge. Immediate assessment of unidentified bleeding sources is essential in blunt trauma patients with hemorrhagic shock. Chest/pelvic X-ray in conjunction with ultrasonography have been established classically as initial diagnostic imaging modalities to identify the major sources of internal bleeding including intra-thoracic, intra-abdominal, or retroperitoneal hemorrhage related to pelvic fracture. Massive soft tissue injury, regardless of whether isolated or associated with multiple injuries, occasionally causes extensive hemorrhage and acute traumatic coagulopathy. Specific types of injuries, including soft tissue injury or retroperitoneal hemorrhage unrelated to pelvic fracture, can potentially be overlooked or be considered “occult” causes of bleeding because classical diagnostic imaging often cannot exclude such injuries. The purpose of this narrative review article is to describe “occult” or unusual sources of bleeding associated with blunt trauma.
Keywords soft tissue injury subcutaneous hematoma non-cavitary hemorrhage retroperitoneal hemorrhage hemorrhagic shock
Amo Type Review
Published Date 2017-10
Publication Title Acta Medica Okayama
Volume volume71
Issue issue5
Publisher Okayama University Medical School
Start Page 363
End Page 368
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 29042693
JaLCDOI 10.18926/AMO/54590
FullText URL 70_5_331.pdf
Author Iida, Atsuyoshi| Nosaka, Nobuyuki| Yumoto, Tetsuya| Knaup, Emily| Naito, Hiromichi| Nishiyama, Chihiro| Yamakawa, Yasuaki| Tsukahara, Kohei| Terado, Michihisa| Sato, Keiji| Ugawa, Toyomu| Nakao, Atsunori|
Abstract In recent years, it has become evident that molecular hydrogen is a particularyl effective treatment for various disease models such as ischemia-reperfusion injury; as a result, research on hydrogen has progressed rapidly. Hydrogen has been shown to be effective not only through intake as a gas, but also as a liquid medication taken orally, intravenously, or locally. Hydrogenʼs effectiveness is thus multifaceted. Herein we review the recent research on hydrogen-rich water, and we examine the possibilities for its clinical application. Now that hydrogen is in the limelight as a gaseous signaling molecule due to its potential ability to inhibit oxidative stress signaling, new research developments are highly anticipated.
Keywords hydrogen antioxidant effect medical gas gaseous signaling molecule clinical tests
Amo Type Review
Published Date 2016-10
Publication Title Acta Medica Okayama
Volume volume70
Issue issue5
Publisher Okayama University Medical School
Start Page 331
End Page 337
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 27777424
Web of Science KeyUT 000388098700001
JaLCDOI 10.18926/AMO/53673
FullText URL 69_5_275.pdf
Author Nosaka, Nobuyuki| Goda, Yu| Knaup, Emily| Tsukahara, Kohei| Yumoto, Tetsuya| Ugawa, Toyomu| Ujike, Yoshihito|
Abstract We sought to identify the incidence, injury patterns, and financial burden of ladder fall injuries to provide a reference for reinforcing guidelines on the prevention of such injuries. We enrolled the patients who were injured in a ladder-related fall and required intensive care between April 2012 and March 2014 at Okayama University Hospital, a tertiary care hospital in Okayama City:9 patients injured in 7 stepladder falls and 2 straight ladder falls. The median patient age was 69 years, and 8 were males. Six falls occurred in non-occupational settings. Head injuries predominated, and the injury severity score ranged from 2 to 35 (mean=21±12). At the time of discharge from the intensive care unit, one patient had died and 5 patients had some neurological disabilities. The case fatality rate was 11%. The total cost of care during the review period was ¥16,705,794, with a mean cost of ¥1,856,199 per patient. Ladder fall injuries are associated with a high rate of neurological sequelae and pose a financial burden on the health insurance system. A prevention education campaign targeting at older-aged males in non-occupational settings may be a worthwhile health service investment in this community.
Keywords accidental falls accident prevention hospital costs injuries ladder
Amo Type Original Article
Published Date 2015-10
Publication Title Acta Medica Okayama
Volume volume69
Issue issue5
Publisher Okayama University Medical School
Start Page 275
End Page 278
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 26490024
Web of Science KeyUT 000365519600003
JaLCDOI 10.18926/AMO/53557
FullText URL 69_4_213.pdf
Author Yumoto, Tetsuya| Sato, Keiji| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito|
Abstract Hyponatremia, a common electrolyte disorder associated with traumatic brain injuries (TBIs), has high mortality and morbidity rates. The aim of this study was to identify the risk factors for hyponatremia associated with TBI. We retrospectively analyzed the cases of TBI patients who were admitted to the emergency intensive care unit at Okayama University Hospital between October 2011 and September 2014. A total of 82 TBI patients were enrolled. The incidences of hyponatremia (serum sodium level of<135mEq/L) and severe hyponatremia (serum sodium level of<130mEq/L) within the first 14 days after admission were 51オ (n=42) and 20オ (n=16), respectively. After admission, hyponatremia took a median period of 7 days to develop and lasted for a median of 3 days. Multivariate analysis demonstrated that higher fluid intake from days 1 to 3 and the presence of cranial fractures were risk factors for hyponatremia. The 58 patients with hyponatremia experienced fewer ventilator-free days, longer intensive care unit stays, and less favorable outcomes compared to the 24 patients without hyponatremia;however, these differences were not significant. Further studies are needed to determine the optimal management strategy for TBI-associated hyponatremia in the intensive care unit setting.
Keywords traumatic brain injury hyponatremia cranial fracture fluid intake
Amo Type Original Article
Published Date 2015-08
Publication Title Acta Medica Okayama
Volume volume69
Issue issue4
Publisher Okayama University Medical School
Start Page 213
End Page 218
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 26289912
Web of Science KeyUT 000365519100004
JaLCDOI 10.18926/AMO/53021
FullText URL 68_6_323.pdf
Author Hirayama, Takahiro| Nagano, Osamu| Shiba, Naoki| Yumoto, Tetsuya| Sato, Keiji| Terado, Michihisa| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito|
Abstract In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH<sub>2</sub>O) with or without a resistor (20cmH<sub>2</sub>O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV.
Keywords HFOV mean lung pressure mean airway pressure
Amo Type Original Article
Published Date 2014-12
Publication Title Acta Medica Okayama
Volume volume68
Issue issue6
Publisher Okayama University Medical School
Start Page 323
End Page 329
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25519026
Web of Science KeyUT 000346882200002
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/53132