Author Kiyota, Hiromasa|
Published Date 2017-02-01
Publication Title Scientific Reports of the Faculty of Agriculture, Okayama University
Volume volume106
Content Type Departmental Bulletin Paper
Title Alternative Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus Species
FullText URL srfa_108_001_004.pdf
Author Kiyota, Hiromasa| Saito, Akihito| Takai, Momoko| Kuwahara, Shigefumi|
Abstract Synthetic studies of ancistrocladinium A and B, antileishmanial compounds isolated from a Congolese Ancistrocladus sp., are described. Buchwald‒Hartwig coupling reaction between the dihydroisoquinoline and the naphthyl triflate failed. The main framework of ancistrocladinium A was constructed by 1,2‒addition of the amine to the naphthoquinone in the presence of celium trichloride as a catalyst. On the other hand, 1,4‒addition of the amine to the naphthoquinone proceeded without catalyst to form the framework of B. These products will be valuable leads for antileishmanial agents.
Keywords ancistrocladinium A and B synthetic studies leishmania, Ancistrocladus isoquinoline
Publication Title Scientific Reports of the Faculty of Agriculture, Okayama University
Published Date 2019-02-01
Volume volume108
Start Page 1
End Page 4
ISSN 2186-7755
language 日本語
File Version publisher
FullText URL 17P-SO3-Sia-SR.pdf
Author Vavricka, Christopher J.| Muto, Chiaki| Hasunuma, Tomohisa| Kimura, Yoshinobu| Araki, Michihiro| Wu, Yan| Gao, George F.| Ohrui, Hiroshi| Izumi, Minoru| Kiyota, Hiromasa|
Keywords Antiviral agents Drug discovery and development Glycosides
Published Date 2017-08
Publication Title Scientific Reports
Volume volume7
Issue issue1
Publisher Nature Publishing Group
Start Page 8239
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 28811524
DOI 10.1038/s41598-017-07836-y
Web of Sience KeyUT 000407570000116
Related Url https://doi.org/10.1038/s41598-017-07836-y
FullText URL Sci_Rep_15_7_8239.pdf
Author Vavrick, Christopher J.| Muto, Chiaki| Hasunuma, Tomohisa| Kimura, Yoshinobu| Araki, Michihiro| Wu, Yan| Gao, George F.| Ohrui, Hiroshi| Izumi, Minoru| Kiyota, Hiromasa|
Note This is an article published by Science
Published Date 2017-08
Publication Title Scientific Reports
Volume volume7
Issue issue1
Publisher Nature Publishing Group
Start Page 8239
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 28811524
DOI 10.1038/s41598-017-07836-y
Web of Sience KeyUT 000407570000116
Related Url https://doi.org/10.1038/s41598-017-07836-y
Author Wu, Yi-Bing| Liu, Dan| Liu, Pei-Yu| Yang, Xue-Mei| Liao, Man| Lu, Nan-Nan| Sauriol, FranÅoise| Gu, Yu-Cheng| Shi, Qing-Wen| Kiyota, Hiromasa| Dong, Mei|
Published Date 2015-05-26
Publication Title Helvetica Chimica Acta
Volume volume98
Issue issue5
Content Type Journal Article