ID | 47085 |
FullText URL | |
Title Alternative | Significance of reduction surgery in multidisciplinary treatment of advanced hepatocellular carcinoma with multiple intrahepatic metastases : A case report
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Author |
Satoh, Daisuke
Umeda, Yuzo
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Abstract | We report a case of advanced HCC with multiple intrahepatic metastases who obtained long-term survival by reductive hepatic resection as part of a multidisciplinary treatment. The patient was a 75-year-old man who had HCC, 13.5 cm in diameter in the right lobe of the liver with multiple intrahepatic metastases around the main tumor and 7 intrahepatic metastases in the left lobe of the liver. The large main tumor and intrahepatic metastases around the main tumor were initially resected by right lobectomy as reduction surgery. Transcatheter arterial chemoembolization (TACE) with epirubicin for intrahepatic metastases in the remnant liver was started 1 month after initial hepatectomy and repeated every 3 months. Twelve months after initial hepatectomy, lung metastases appeared, so we started systemic chemotherapy with 5-fluorouracil (5-FU) and cisplatin (CDDP). In addition, we changed epirubicin to CDDP for TACE. Despite this combination therapy, 20 months after the initial hepatectomy, the lung metastases showed an increase in size. We decided to discontinue systemic chemotherapy and administer sorafenib. The patient was alive without progression of intrahepatic metastasis and lung metastasis more than 26 months after the initial hepatectomy.
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Keywords | 進行肝細胞癌 (advanced hepatocellular carcinoma)
減量手術 (reduction surgery)
肝動脈塞栓療法 (transcatheter arterial chemoembolization : TACE)
ソラフェニブ (sorafenib)
集学的治療 (multidisciplinary treatment)
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Note | 症例報告 (Case Report)
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Published Date | 2011-12-01
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume123
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Issue | issue3
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 213
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End Page | 216
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ISSN | 0030-1558
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NCID | AN00032489
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Content Type |
Journal Article
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Related Url | http://www.okayama-u.ac.jp/user/oma/
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language |
Japanese
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Copyright Holders | Copyright (c) 2011 岡山医学会
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File Version | publisher
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Refereed |
True
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DOI | |
Eprints Journal Name | joma
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