start-ver=1.4
cd-journal=joma
no-vol=2012
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=2012
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Inhibitory Effects of Pretreatment with Radon on Acute Alcohol-Induced Hepatopathy in Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We previously reported that radon inhalation activates antioxidative functions in the liver and inhibits carbon tetrachloride-induced hepatopathy in mice. In addition, it has been reported that reactive oxygen species contribute to alcohol-induced hepatopathy. In this study, we examined the inhibitory effects of radon inhalation on acute alcohol- induced hepatopathy in mice. C57BL/6J mice were subjected to intraperitoneal injection of 50% alcohol (5 g/kg bodyweight) after inhaling approximately 4000 Bq/m(3) radon for 24 h. Alcohol administration significantly increased the activities of glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT) in serum, and the levels of triglyceride and lipid peroxide in the liver, suggesting acute alcohol- induced hepatopathy. Radon inhalation activated antioxidative functions in the liver. Furthermore, pretreatment with radon inhibited the depression of hepatic functions and antioxidative functions. These findings suggested that radon inhalation activated antioxidative functions in the liver and inhibited acute alcohol- induced hepatopathy in mice.
en-copyright=
kn-copyright=
en-aut-name=ToyotaTeruaki
en-aut-sei=Toyota
en-aut-mei=Teruaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=Okayama Univ, Grad Sch Hlth Sci
affil-num=2
en-affil=
kn-affil=Okayama Univ, Grad Sch Hlth Sci
affil-num=3
en-affil=
kn-affil=Okayama Univ, Grad Sch Hlth Sci
affil-num=4
en-affil=
kn-affil=Okayama Univ, Grad Sch Hlth Sci
affil-num=5
en-affil=
kn-affil=Okayama Univ, Grad Sch Hlth Sci
END
start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=6
article-no=
start-page=359
end-page=367
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=201312
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=In Vitro Assessment of Factors Affecting the Apparent Diffusion Coefficient of Jurkat Cells Using Bio-phantoms
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It is well known that many tumor tissues show lower apparent diffusion coefficient (ADC) values, and that several factors are involved in the reduction of ADC values. The aim of this study was to clarify how much each factor contributes to decreases in ADC values. We investigate the roles of cell density, extracellular space, intracellular factors, apoptosis and necrosis in ADC values using bio-phantoms. The ADC values of bio-phantoms, in which Jurkat cells were encapsulated by gellan gum, were measured
by a 1.5-Tesla magnetic resonance imaging device with constant diffusion time of 30sec. Heating at 42℃ was used to induce apoptosis while heating at 48℃ was used to induce necrosis. Cell death after heating was evaluated by flow cytometric analysis and electron microscopy. The ADC values of bio-phantoms including non-heated cells decreased linearly with increases in cell density, and showed a steep decline when the distance between cells became less than 3μm. The analysis of ADC values of cells after destruction of cellular structures by sonication suggested that approximately two-thirds of the ADC values of cells originate from their cellular structures. The ADC values of bio-phantoms including necrotic cells increased while those including apoptotic cells decreased. This study quantitatively
clarified the role of the cellular factors and the extracellular space in determining the ADC values
produced by tumor cells. The intermediate diffusion time of 30msec might be optimal to distinguish
between apoptosis and necrosis.
en-copyright=
kn-copyright=
en-aut-name=KatashimaKazunori
en-aut-sei=Katashima
en-aut-mei=Kazunori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=AshidaMasakazu
en-aut-sei=Ashida
en-aut-mei=Masakazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=SasakiTakanori
en-aut-sei=Sasaki
en-aut-mei=Takanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=MatsuzakiHidenobu
en-aut-sei=Matsuzaki
en-aut-mei=Hidenobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=MurakamiJun
en-aut-sei=Murakami
en-aut-mei=Jun
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=YanagiYoshinobu
en-aut-sei=Yanagi
en-aut-mei=Yoshinobu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=HisatomiMiki
en-aut-sei=Hisatomi
en-aut-mei=Miki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=HaraMarina
en-aut-sei=Hara
en-aut-mei=Marina
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=KatoHirokazu
en-aut-sei=Kato
en-aut-mei=Hirokazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=OhmuraYuichi
en-aut-sei=Ohmura
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
en-aut-name=KobayashiTomoki
en-aut-sei=Kobayashi
en-aut-mei=Tomoki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=
en-aut-name=KanazawaSusumu
en-aut-sei=Kanazawa
en-aut-mei=Susumu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=
en-aut-name=HaradaSosuke
en-aut-sei=Harada
en-aut-mei=Sosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=
en-aut-name=TakemotoMitsuhiro
en-aut-sei=Takemoto
en-aut-mei=Mitsuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=16
ORCID=
en-aut-name=OhnoSeiichiro
en-aut-sei=Ohno
en-aut-mei=Seiichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=17
ORCID=
en-aut-name=MimuraSeiichi
en-aut-sei=Mimura
en-aut-mei=Seiichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=18
ORCID=
en-aut-name=AsaumiJunichi
en-aut-sei=Asaumi
en-aut-mei=Junichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=19
ORCID=
affil-num=1
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=2
en-affil=
kn-affil=Radiological Technology, Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=4
en-affil=
kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=5
en-affil=
kn-affil=Radiological Technology, Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=7
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=8
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=9
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=10
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=11
en-affil=
kn-affil=Radiological Technology, Graduate School of Health Sciences, Okayama University
affil-num=12
en-affil=
kn-affil=Radiological Technology, Graduate School of Health Sciences, Okayama University
affil-num=13
en-affil=
kn-affil=Radiological Technology, Graduate School of Health Sciences, Okayama University
affil-num=14
en-affil=
kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=15
en-affil=
kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=16
en-affil=
kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=17
en-affil=
kn-affil=Central Division of Radiology, Okayama University Hospital
affil-num=18
en-affil=
kn-affil=Central Division of Radiology, Okayama University Hospital
affil-num=19
en-affil=
kn-affil=Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
en-keyword=ADC
kn-keyword=ADC
en-keyword=apoptosis
kn-keyword=apoptosis
en-keyword=necrosis
kn-keyword=necrosis
en-keyword=hyperthermia
kn-keyword=hyperthermia
en-keyword=cell density
kn-keyword=cell density
END
start-ver=1.4
cd-journal=joma
no-vol=53
cd-vols=
no-issue=6
article-no=
start-page=830
end-page=839
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Comparative study on the inhibitory effects of antioxidant vitamins and radon on carbon tetrachloride-induced hepatopathy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We have previously reported that radon inhalation activates anti-oxidative functions and inhibits carbon tetrachloride (CCl(4))-induced hepatopathy. It has also been reported that antioxidant vitamins can inhibit CCl(4)-induced hepatopathy. In the current study, we examined the comparative efficacy of treatment with radon, ascorbic acid and α-tocopherol on CCl(4)-induced hepatopathy. Mice were subjected to intraperitoneal injection of CCl(4) after inhaling approximately 1000 or 2000 Bq/m(3) radon for 24 h, or immediately after intraperitoneal injection of ascorbic acid (100, 300, or 500 mg/kg bodyweight) or α-tocopherol (100, 300, or 500 mg/kg bodyweight). We estimated the inhibitory effects on CCl(4)-induced hepatopathy based on hepatic function-associated parameters, oxidative damage-associated parameters and histological changes. The results revealed that the therapeutic effects of radon inhalation were almost equivalent to treatment with ascorbic acid at a dose of 500 mg/kg or α-tocopherol at a dose of 300 mg/kg. The activities of superoxide dismutase, catalase, and glutathione peroxidase in the liver were significantly higher in mice exposed to radon than in mice treated with CCl(4) alone. These findings suggest that radon inhalation has an anti-oxidative effect against CCl(4)-induced hepatopathy similar to the anti-oxidative effects of ascorbic acid or α-tocopherol due to the induction of anti-oxidative functions.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=YamatoKeiko
en-aut-sei=Yamato
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TeraokaJunichi
en-aut-sei=Teraoka
en-aut-mei=Junichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=MoriiYuji
en-aut-sei=Morii
en-aut-mei=Yuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=7
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=8
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=9
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=Radon
kn-keyword=Radon
en-keyword=ascorbic acid
kn-keyword=ascorbic acid
en-keyword=α-tocopherol
kn-keyword=α-tocopherol
en-keyword=antioxidant
kn-keyword=antioxidant
en-keyword=hepatopathy
kn-keyword=hepatopathy
END
start-ver=1.4
cd-journal=joma
no-vol=34
cd-vols=
no-issue=9
article-no=
start-page=1181
end-page=1187
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201210
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Comparative Study on the Inhibitory Effects of α-Tocopherol and Radon on Carbon Tetrachloride-Induced Renal Damage
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Since the 2011 nuclear accident in Fukushima, the effects of low-dose irradiation, especially internal exposure, are at the forefront of everyone’s attention. However, low-dose radiation induced various stimulating effects such as activation of antioxidative and immune functions. In this study, we attempted to evaluate the quantitative effects of the activation of antioxidative activities in kidney induced by radon inhalation on carbon tetrachloride (CCl4)-induced renal damage. Mice were subjected to intraperitoneal (i.p.) injection of CCl4 after inhaling approximately 1000 or 2000 Bq/m3 radon for 24 h, or immediately after i.p. injection of α-tocopherol (100, 300, or 500 mg/kg bodyweight). In case of renal function, radon inhalation at a concentration of 2000 Bq/m3 has the inhibitory effects similar to α-tocopherol treatment at a dose of 300?500 mg/kg bodyweight. The activities of superoxide dismutase and catalase in kidneys were significantly higher in mice exposed to radon as compared to mice treated with CCl4 alone. These findings suggest that radon inhalation has an antioxidative effect against CCl4-induced renal damage similar to the antioxidative effects of α-tocopherol due to induction of antioxidative functions.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=YamatoKeiko
en-aut-sei=Yamato
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=MoriiYuji
en-aut-sei=Morii
en-aut-mei=Yuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=EtaniReo
en-aut-sei=Etani
en-aut-mei=Reo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=TakataYuji
en-aut-sei=Takata
en-aut-mei=Yuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=KawabeAtsuishi
en-aut-sei=Kawabe
en-aut-mei=Atsuishi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=7
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=8
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=9
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=10
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=11
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=12
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=radon
kn-keyword=radon
en-keyword=carbon tetrachloride
kn-keyword=carbon tetrachloride
en-keyword=oxidative damage
kn-keyword=oxidative damage
en-keyword=α-tocopherol
kn-keyword=α-tocopherol
en-keyword=kidney
kn-keyword=kidney
END
start-ver=1.4
cd-journal=joma
no-vol=146
cd-vols=
no-issue=1-3
article-no=
start-page=360
end-page=363
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=201107
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Our previous studies showed the possibility that activation of the antioxidative function alleviates various oxidative damages, which are related to lifestyle diseases. Results showed that, low-dose X-ray irradiation activated superoxide dismutase and inhibits oedema following ischaemia-reperfusion. To alleviate ischaemia-reperfusion injury with transplantation, the changes of the antioxidative function in liver graft using low-dose X-ray irradiation immediately after exenteration were examined. Results showed that liver grafts activate the antioxidative function as a result of irradiation. In addition, radon inhalation enhances the antioxidative function in some organs, and alleviates alcohol-induced oxidative damage of mouse liver. Moreover, in order to determine the most effective condition of radon inhalation, mice inhaled radon before or after carbon tetrachloride (CCl4) administration. Results showed that radon inhalation alleviates CCl4-induced hepatopathy, especially prior inhalation. It is highly possible that adequate activation of antioxidative functions induced by low-dose irradiation can contribute to preventing or reducing oxidative damages, which are related to lifestyle diseases.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=YoshimotoMasaaki
en-aut-sei=Yoshimoto
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=NakagawaShinya
en-aut-sei=Nakagawa
en-aut-mei=Shinya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=ToyotaTeruaki
en-aut-sei=Toyota
en-aut-mei=Teruaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=YamatoKeiko
en-aut-sei=Yamato
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=KawabeAtsushi
en-aut-sei=Kawabe
en-aut-mei=Atsushi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Sakakibara Heart Institute of Okayama
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=7
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=8
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center
affil-num=9
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=10
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=11
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=12
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
END
start-ver=1.4
cd-journal=joma
no-vol=45
cd-vols=
no-issue=2
article-no=
start-page=219
end-page=226
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=200909
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Basic Study on Active Changes in Biological Function of Mouse Liver Graft in Cold Storage after Low-Dose X-Irradiation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We previously reported that low-dose X-irradiation alleviates ischemia-reperfusion injury such as mouse paw edema. In this study, we examined active changes in the biological function of mouse liver grafts in cold storage after low-dose X-irradiation. Mouse livers were sham-irradiated or were irradiated with 0.25, 0.5, 1.0, or 5.0 Gy of X-ray and stored for 4, 8, 24, or 48 h in preservation or saline solution. The results show that storage for 24 h in saline solution after 0.5 Gy irradiation significantly increased the activity of superoxide dismutase (SOD) and catalase. Following storage for 4, 8, or 48 h in preservation solution, lipid peroxide levels of the 0.5 Gy irradiated group were significantly lower than those of the sham irradiated group. Following storage for 24 h in preservation solution, the activity of SOD and catalase of the 1.0 Gy irradiated group were significantly higher than those of the sham irradiated group. Hepatocytes stored in saline solution were vacuolated. However, no vacuole formation was observed in hepatocytes stored in preservation solution. These findings suggest that low-dose irradiation significantly activates antioxidative functions of liver grafts. Moreover, the dose at which enhancement of antioxidative function occurs in livers stored in preservation solution, which contains glutathione, is significantly higher than that in saline solution.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=YoshimotoMasaaki
en-aut-sei=Yoshimoto
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NakagawaShinya
en-aut-sei=Nakagawa
en-aut-mei=Shinya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=MizuguchiYuko
en-aut-sei=Mizuguchi
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Radiation Safety Research Center, Central Research Institute of Electric Power Industry
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=organ transplantation
kn-keyword=organ transplantation
en-keyword=low-dose irradiation
kn-keyword=low-dose irradiation
en-keyword=antioxidative function
kn-keyword=antioxidative function
en-keyword=hepatopathy
kn-keyword=hepatopathy
END
start-ver=1.4
cd-journal=joma
no-vol=43
cd-vols=
no-issue=1
article-no=
start-page=41
end-page=49
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2008
dt-pub=200807
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=No Different Sensitivity in Terms of Whole-Body Irradiation between Normal and Acatalasemic Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=To elucidate the radiosensitivity of an acatalasemic mouse, we examined the time and dose-dependency in the survival rates, the lymphocytes and the intestinal epithelial cells, and the antioxidant function after 3.0 to 12.0 Gy whole body irradiation. Results showed that no significant differences between acatalasemic mice and normal mice were observed in the survival rates and the histological changes in spleens and small intestine after each irradiation. The catalase activities in livers and spleens of acatalasemic mice were significantly lower than those of normal mice and the glutathione peroxidase activity in livers of acatalasemic mice was significantly higher than that of normal mice. At 10 days after 6.0 Gy irradiation, the catalase activities in livers of acatalasemic and normal mice and that in spleens of normal mice significantly decreased compared with no-irradiation control, and there were no differences between those catalase activities. The total glutathione content in acatalasemic mice was significantly higher than that in normal mice at 10 days after 6.0 Gy irradiation. These findings suggested that the radiosensitivity of acatalasemic mice in terms of whole body irradiation doesn’t significantly differ from that of normal mice, probably due to compensated sufficient contents of glutathione peroxidase and total glutathione in acatalasemic mice.
en-copyright=
kn-copyright=
en-aut-name=NakagawaShinya
en-aut-sei=Nakagawa
en-aut-mei=Shinya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=MizuguchiYuko
en-aut-sei=Mizuguchi
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=YoshimotoMasaaki
en-aut-sei=Yoshimoto
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NomuraTakaharu
en-aut-sei=Nomura
en-aut-mei=Takaharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=WangDa-Hong
en-aut-sei=Wang
en-aut-mei=Da-Hong
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=KawabeAtsushi
en-aut-sei=Kawabe
en-aut-mei=Atsushi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Radiation Safety Research Center, Central Research Institute of Electric Power Industry
affil-num=7
en-affil=
kn-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
affil-num=8
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=9
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=10
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=acatalasemic mouse
kn-keyword=acatalasemic mouse
en-keyword=radiosensitivity
kn-keyword=radiosensitivity
en-keyword=catalase
kn-keyword=catalase
en-keyword=glutathione peroxidase
kn-keyword=glutathione peroxidase
en-keyword=total glutathione
kn-keyword=total glutathione
END
start-ver=1.4
cd-journal=joma
no-vol=48
cd-vols=
no-issue=6
article-no=
start-page=505
end-page=513
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2007
dt-pub=20071121
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Inhibitory Effects of Prior Low-dose X-irradiation on Ischemia-reperfusion Injury in Mouse Paw
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We have reported that low-dose, unlike high-dose, irradiation enhanced antioxidation function and reduced oxidative damage. On the other hand, ischemia-reperfusion injury is induced by reactive oxygen species. In this study, we examined the inhibitory effects of prior low-dose X-irradiation on ischemia-reperfusion injury in mouse paw. BALB/c mice were irradiated by sham or 0.5 Gy of X-ray. At 4 hrs after irradiation, the left hind leg was bound 10 times with a rubber ring for 0.5, 1, or 2 hrs and the paw thickness was measured. Results show that the paw swelling thickness by ischemia for 0.5 hr was lower than that for 2 hrs. At 1 hr after reperfusion from ischemia for 1 hr, superoxide dismutase activity in serum was increased in those mice which received 0.5 Gy irradiation and in the case of the ischemia for 0.5 or 1 hr, the paw swelling thicknesses were inhibited by 0.5 Gy irradiation. In addition, interstitial edema in those mice which received 0.5 Gy irradiation was less than that in the mice which underwent by sham irradiation. These findings suggest that the ischemia-reperfusion injury is inhibited by the enhancement of antioxidation function by 0.5 Gy irradiation.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=MizuguchiYuko
en-aut-sei=Mizuguchi
en-aut-mei=Yuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=YoshimotoMasaaki
en-aut-sei=Yoshimoto
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=Edema
kn-keyword=Edema
en-keyword=Ischemia-reperfusion injury
kn-keyword=Ischemia-reperfusion injury
en-keyword=Low-dose irradiation
kn-keyword=Low-dose irradiation
en-keyword=Reactive oxygen species
kn-keyword=Reactive oxygen species
en-keyword=Antioxidation function
kn-keyword=Antioxidation function
END
start-ver=1.4
cd-journal=joma
no-vol=45
cd-vols=
no-issue=1
article-no=
start-page=89
end-page=95
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040507
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Inhibitory Effects of Prior Low-dose X-ray Irradiation on Carbon Tetrachloride-induced Hepatopathy in Acatalasemic Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The catalase activities in blood and organs of the acatalasemic (C3H/AnLCsbCsb) mouse of C3H strain are lower than those of the normal (C3H/AnLCsaCsa) mouse. We examined the effects of prior low-dose (0.5 Gy) X-ray irradiation, which reduced the oxidative damage under carbon tetrachloride-induced hepatopathy in the acatalasemic or normal mice. The acatalasemic mice showed a significantly lower catalase activity and a significantly higher glutathione peroxidase activity compared with those in the normal mice. Moreover, low-dose irradiation increased the catalase activity in the acatalasemic mouse liver to a level similar to that of the normal mouse liver. Pathological examinations and analyses of blood glutamic oxaloacetic and glutamic pyruvic transaminase activity and lipid peroxide levels showed that carbon tetrachloride induced hepatopathy was inhibited by low-dose irradiation. These findings may indicate that the free radical reaction induced by the lack of catalase and the administration of carbon tetrachloride is more properly neutralized by high glutathione peroxidase activity and low-dose irradiation in the acatalasemic mouse liver.
en-copyright=
kn-copyright=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NomuraTakaharu
en-aut-sei=Nomura
en-aut-mei=Takaharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=WangDa-Hong
en-aut-sei=Wang
en-aut-mei=Da-Hong
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=MoriShuji
en-aut-sei=Mori
en-aut-mei=Shuji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=HanamotoKatsumi
en-aut-sei=Hanamoto
en-aut-mei=Katsumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=KiraShohei
en-aut-sei=Kira
en-aut-mei=Shohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=2
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=3
en-affil=
kn-affil=Low Dose Radiation Research Center, Central Research Institute of Electric Power Industry
affil-num=4
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=5
en-affil=
kn-affil=Public Health, Okayama University Medical School
affil-num=6
en-affil=
kn-affil=Pharmacology, Okayama University Medical School
affil-num=7
en-affil=
kn-affil=Chair of Medical Radioscience, and Department of Public Health and Pharmacology, Okayama University Medical School
affil-num=8
en-affil=
kn-affil=Public Health, Okayama University Medical School
en-keyword=Acatalasemic mouse
kn-keyword=Acatalasemic mouse
en-keyword=Catalase
kn-keyword=Catalase
en-keyword=CCl4
kn-keyword=CCl4
en-keyword=Hepatotoxicity
kn-keyword=Hepatotoxicity
en-keyword=Low-dose X-irradiation
kn-keyword=Low-dose X-irradiation
en-keyword=Antioxidant substances
kn-keyword=Antioxidant substances
END
start-ver=1.4
cd-journal=joma
no-vol=35
cd-vols=
no-issue=2
article-no=
start-page=713
end-page=722
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Protective Effects of Radon Inhalation on Carrageenan-Induced Inflammatory Paw Edema in Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We assessed whether radon inhalation inhibited carrageenan-induced inflammation in mice. Carrageenan (1% v/v) was injected subcutaneously into paws of mice that had or had not inhaled approximately 2,000 Bq/m3 of radon for 24 h. Radon inhalation significantly increased superoxide dismutase (SOD) and catalase activities and significantly decreased lipid peroxide levels in mouse paws, indicating that radon inhalation activates antioxidative functions. Carrageenan administration induced paw edema and significantly increased tumor necrosis factor-alpha (TNF-α) and nitric oxide in serum. However, radon inhalation significantly reduced carrageenan-induced paw edema. Serum TNF-α levels were lower in the radon-treated mice than in sham-treated mice. In addition, SOD and catalase activities in paws were significantly higher in the radon-treated mice than in the sham-treated mice. These findings indicated that radon inhalation had anti-inflammatory effects and inhibited carrageenan-induced inflammatory paw edema.
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=TeraokaJunichi
en-aut-sei=Teraoka
en-aut-mei=Junichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamatoKeiko
en-aut-sei=Yamato
en-aut-mei=Keiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=MondenMayuko
en-aut-sei=Monden
en-aut-mei=Mayuko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=NomuraTakaharu
en-aut-sei=Nomura
en-aut-mei=Takaharu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
affil-num=7
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency
affil-num=8
en-affil=
kn-affil=Radiation Safety Research Center, Central Research Institute of Electric Power Industry
affil-num=9
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=10
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=radon inhalation
kn-keyword=radon inhalation
en-keyword=inflammation
kn-keyword=inflammation
en-keyword=carrageenan
kn-keyword=carrageenan
en-keyword=edema
kn-keyword=edema
en-keyword=antioxidative function
kn-keyword=antioxidative function
END
start-ver=1.4
cd-journal=joma
no-vol=34
cd-vols=
no-issue=6
article-no=
start-page=559
end-page=567
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20111201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Radon Inhalation Protects Mice from Carbon-Tetrachloride-Induced Hepatic and Renal Damage
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=NishiyamaYuichi
en-aut-sei=Nishiyama
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=ToyotaTeruaki
en-aut-sei=Toyota
en-aut-mei=Teruaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=YoshimotoMasaaki
en-aut-sei=Yoshimoto
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=SakodaAkihiro
en-aut-sei=Sakoda
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=IshimoriYuu
en-aut-sei=Ishimori
en-aut-mei=Yuu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=AoyamaYutaka
en-aut-sei=Aoyama
en-aut-mei=Yutaka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=6
en-affil=
kn-affil=Ningyo-toge Environmental Engineering Center
affil-num=7
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=8
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=9
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=radon inhalation
kn-keyword=radon inhalation
en-keyword=ascorbic acid
kn-keyword=ascorbic acid
en-keyword=carbon tetrachloride
kn-keyword=carbon tetrachloride
en-keyword=antioxidative function
kn-keyword=antioxidative function
en-keyword=liver
kn-keyword=liver
END
start-ver=1.4
cd-journal=joma
no-vol=35
cd-vols=
no-issue=1
article-no=
start-page=89
end-page=97
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20120201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Inhibitory Effects of Prior Low-dose X-irradiation on Cold-induced Brain Injury in Mouse
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We examined the inhibitory effects of low-dose X-irradiation on mouse brain tissue with cold-induced injury by comparing tissue samples from three groups of mice: control, sham-irradiated cold-exposed, and X-ray-irradiated (0.5 Gy) cold-exposed mice. The water content in brain increased significantly in the sham-irradiated group following the cold-induced injury relative to the control group. However, water content in brain tissue from the X-ray-irradiated group was significantly lower than that from the sham-irradiated group. Levels of antioxidants, such as superoxide dismutase and glutathione, in brain tissue from the X-ray-irradiated group were higher than those from the sham-irradiated group. Moreover, the cold injury-induced cell death, particularly apoptosis, while low-dose irradiation inhibited cell death, especially among glial cells, but not numeral cells. These findings suggest that prior low-dose X-irradiation activated antioxidant function and inhibited cold-induced brain injury.
en-copyright=
kn-copyright=
en-aut-name=YoshimotoMasaaki
en-aut-sei=Yoshimoto
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KataokaTakahiro
en-aut-sei=Kataoka
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=ToyotaTeruaki
en-aut-sei=Toyota
en-aut-mei=Teruaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamaokaKiyonori
en-aut-sei=Yamaoka
en-aut-mei=Kiyonori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=2
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=3
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=4
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
affil-num=5
en-affil=
kn-affil=Graduate School of Health Sciences, Okayama University
en-keyword=cold injury
kn-keyword=cold injury
en-keyword=brain edema
kn-keyword=brain edema
en-keyword=0.5 Gy irradiation
kn-keyword=0.5 Gy irradiation
en-keyword=antioxidative function
kn-keyword=antioxidative function
END
start-ver=1.4
cd-journal=joma
no-vol=54
cd-vols=
no-issue=3
article-no=
start-page=111
end-page=118
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2000
dt-pub=200006
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=The perineuronal proteoglycan surface coat in the adult rat brain, with special reference to its reactions to Gomori's ammoniacal silver.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The present study showed that many neurons in the adult rat brain possessed a perineuronal sulfated proteoglycan surface coat which reacted to cationic iron colloid and aldehyde fuchsin. This surface coat was stained supravitally with Ehrlich's methylene blue and doubly stained with Ehrlich's methylene blue and aldehyde fuchsin. The surface coat was also stained with Gomori's ammoniacal silver and doubly stained with Gomori's ammoniacal silver and cationic iron colloid. The surface coat was usually expressed together with a nerve cell surface glycoprotein net detectable with lectin Wisteria floribunda agglutinin. These findings indicate that the perineuronal proteoglycan surface coat is identical to Cajal's superficial reticulum and contains some collagenous elements. It was further demonstrated that collagenase digestion erased Gomori's ammoniacal silver impregnation within the perineuronal proteoglycan surface coat.
en-copyright=
kn-copyright=
en-aut-name=EndoRyutaro
en-aut-sei=Endo
en-aut-mei=Ryutaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=MurakamiShinichiro
en-aut-sei=Murakami
en-aut-mei=Shinichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=MasudaYu
en-aut-sei=Masuda
en-aut-mei=Yu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NishizakiKazunori
en-aut-sei=Nishizaki
en-aut-mei=Kazunori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
affil-num=1
en-affil=
kn-affil=Okayama University
affil-num=2
en-affil=
kn-affil=Okayama University
affil-num=3
en-affil=
kn-affil=Okayama University
affil-num=4
en-affil=
kn-affil=Okayama University
affil-num=5
en-affil=
kn-affil=Okayama University
affil-num=6
en-affil=
kn-affil=Okayama University
affil-num=7
en-affil=
kn-affil=Okayama University
en-keyword=brain
kn-keyword=brain
en-keyword=extracellular matrix
kn-keyword=extracellular matrix
en-keyword=perineuronal proteoglycans
kn-keyword=perineuronal proteoglycans
en-keyword=cell surface glycoproteins
kn-keyword=cell surface glycoproteins
END
start-ver=1.4
cd-journal=joma
no-vol=54
cd-vols=
no-issue=6
article-no=
start-page=243
end-page=252
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2000
dt-pub=200012
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Typology of the arteries in the human scalenus region, with special reference to the accessory ascending cervical artery.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The accessory ascending cervical artery (Murakami et al., 1996), which arises from the subclavian artery and ascends between the scalenus anterior and medius muscles, was studied in 87 Japanese adult cadavers (174 sides), with special attention being given to its origin, distribution, and relationship to other arteries at the cervical or scalenus region. In 154 sides (88.5%), the accessory ascending cervical artery was found to originate from the subclavian artery behind the scalenus anterior muscle, and to branch out to the scalenus anterior and medius muscles as well as those entering the 5th and 6th intervertebral foramens along the 6th and 7th cervical nerves. This artery arose independently in 105 sides. The accessory ascending cervical artery issued off or formed a common trunk with the transverse cervical artery and/or costocervical trunk in 49 sides. In cases lacking the accessory ascending cervical artery, it was usually compensated for by the costocervial trunk and/or transverse cervical artery (18 sides). Common trunk formation with the vertebral, internal thoracic, or suprascapular arteries was not observed. The authors suggest that the accessory ascending cervical artery, the transverse cervical artery, and the costocervical trunk should be grouped into one arterial system, a system that may be a remnant of the precostal longitudinal anastomoses of intersegmental arteries of the dorsal aorta behind the scalenus anterior muscle.
en-copyright=
kn-copyright=
en-aut-name=SuWei-Dong
en-aut-sei=Su
en-aut-mei=Wei-Dong
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
affil-num=1
en-affil=
kn-affil=First Clinical Medical College of Harbin Medical University
affil-num=2
en-affil=
kn-affil=Okayama University
affil-num=3
en-affil=
kn-affil=Okayama University
affil-num=4
en-affil=
kn-affil=Okayama University
en-keyword=accessory ascending cervical artery
kn-keyword=accessory ascending cervical artery
en-keyword=transverse cervical artery
kn-keyword=transverse cervical artery
en-keyword=costocervical trunk
kn-keyword=costocervical trunk
en-keyword=scalenus anterior muscle
kn-keyword=scalenus anterior muscle
en-keyword=subclavian artery
kn-keyword=subclavian artery
END
start-ver=1.4
cd-journal=joma
no-vol=41
cd-vols=
no-issue=3
article-no=
start-page=99
end-page=103
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198706
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Palmar interosseous muscle of the human thumb.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The adductor pollicis muscle was studied in fifty hands of Japanese adult cadavers of both sexes. The radial portion of the oblique head of the adductor pollicis muscle has carpal and metacarpal origins and an insertion into the wing tendon of the extensor apparatus. This portion was located dorsal to the palmar metacarpophalangeal articular nerve and superficial palmar metacarpal artery. Thus, the radial portion of the oblique head of the adductor pollicis muscle (more strictly, the slips dorsal to the palmar-penetrating twig of the ulnar nerve) is similar to the palmar interosseous muscles, except that its slips cannot be clearly distinguished from each other.
en-copyright=
kn-copyright=
en-aut-name=YamamotoRyosuke
en-aut-sei=Yamamoto
en-aut-mei=Ryosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
affil-num=1
en-affil=
kn-affil=Okayama University
affil-num=2
en-affil=
kn-affil=Okayama University
affil-num=3
en-affil=
kn-affil=Okayama University
en-keyword=adductor pollicis muscle
kn-keyword=adductor pollicis muscle
en-keyword=palmar interosseous muscle
kn-keyword=palmar interosseous muscle
en-keyword=deep palmar artery
kn-keyword=deep palmar artery
en-keyword=deep palmar nerve
kn-keyword=deep palmar nerve
en-keyword=wing tendon
kn-keyword=wing tendon
END
start-ver=1.4
cd-journal=joma
no-vol=56
cd-vols=
no-issue=5
article-no=
start-page=245
end-page=253
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=200210
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Hepatopancreatic arterial ring: bilateral symmetric typology in human celiaco-mesenteric arterial system.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The celiac and mesenteric arterial system including the left gastric, splenic, common hepatic, and superior mesenteric arteries shows various types of origins, courses, ramifications and anastomoses. In order to explain the various expressions of this system, we have proposed a typological model, in which celiacomesenteric arteries develop as paired or bilaterally symmetrical primordial vessels originated from the anterior aspect of the aorta, and these vessels anastomose each other with longitudinal and horizontal pathways. Here, we report 3 unusual cases characterized by arterial rings, formed by the left gastric, left accessory hepatic, proper hepatic, anterior pancreaticoduodenal, and dorsal pancreatic arteries. The dorsal pancreatic and anterior pancreaticoduodenal arteries are located to the right and left of the embryonic pancreas developing in the dorsal mesentery, respectively. Such hepatopancreatic arterial rings simultaneously containing right and left elements can only be explained using our typological model, in which the concept of paired arteries or bilateral symmetry is introduced.
en-copyright=
kn-copyright=
en-aut-name=KosakaMotohiro
en-aut-sei=Kosaka
en-aut-mei=Motohiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=HoriuchiKanji
en-aut-sei=Horiuchi
en-aut-mei=Kanji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=NishidaKeiichiro
en-aut-sei=Nishida
en-aut-mei=Keiichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=Okayama University
affil-num=2
en-affil=
kn-affil=Okayama University
affil-num=3
en-affil=
kn-affil=Okayama University
affil-num=4
en-affil=
kn-affil=Okayama University
affil-num=5
en-affil=
kn-affil=Okayama University
affil-num=6
en-affil=
kn-affil=Okayama University
en-keyword=arterial variation
kn-keyword=arterial variation
en-keyword=celiac trunk
kn-keyword=celiac trunk
en-keyword=superior mesenteric artery
kn-keyword=superior mesenteric artery
en-keyword=typology
kn-keyword=typology
en-keyword=bilateral symmetry
kn-keyword=bilateral symmetry
END
start-ver=1.4
cd-journal=joma
no-vol=48
cd-vols=
no-issue=4
article-no=
start-page=195
end-page=197
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1994
dt-pub=199408
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=The occurrence of neurons with strongly negatively charged surface coats in mammalian, avian, reptilian, amphibian and piscine brains.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Neurons with strongly negatively charged surface coats were recognized in mammalian, avian, reptilian, amphibian and piscine brains. Many large-sized neurons had strongly negatively charged surface coats in the visual cortex and brain stem of the cow, cat, guinea pig, mouse, quail and parakeet. Such neurons were also seen in the brain stem of the lower vertebrates such as the house lizard, Japanese terrapin, bullfrog, newt, carp and sweetfish.
en-copyright=
kn-copyright=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=TsubouchiMari
en-aut-sei=Tsubouchi
en-aut-mei=Mari
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=TubouchiYutaka
en-aut-sei=Tubouchi
en-aut-mei=Yutaka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=Okayama University
affil-num=2
en-affil=
kn-affil=Okayama University
affil-num=3
en-affil=
kn-affil=Okayama Univeristy
affil-num=4
en-affil=
kn-affil=Okayama University
affil-num=5
en-affil=
kn-affil=Okayama University
en-keyword=central nervous system
kn-keyword=central nervous system
en-keyword=neurons
kn-keyword=neurons
en-keyword=negatively charged surface coats
kn-keyword=negatively charged surface coats
en-keyword=proteoglycans
kn-keyword=proteoglycans
END
start-ver=1.4
cd-journal=joma
no-vol=100
cd-vols=
no-issue=1-2
article-no=
start-page=187
end-page=194
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1988
dt-pub=1988
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The organization of the elastic tissues of the human and rabbit aorta
kn-title=ヒトとウサギの大動脈弾性組織構築
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The organization of the elastic tissues of the human and rabbit aorta was studied by scanning and transmission electron microscopy of tissues treated with 88% formic acid at 45℃. When the tissues were treated with formic acid until they became semitransparent, fixed tissues showed the same organization of the elastic tissues as unfixed tissues. When tissues were treated with formic acid for a short time, the intimal elastic lamina was observed as a plate with numerous small pores or fenestrae, whereas long treatment revealed that the lamina consisted of a network of elastic fibers. The tunica media consisted of concentrically arranged elastic lamellae. There were 50-60 elastic lamellae in humans and about 30 in the rabbit. The elastic fibers, that consisted of elastic microfibrils, ran longitudinally, repeatedly branching and anastomosing, and formed the network of the elastic lamella. Between the adjacent elastic lamellae stretched interlamellar elastic fibers. Thus, the elastic tissues in the aorta formed an integral network, which seems to be highly associated with the aortic function of distributing the pressure applied to the vascular wall. Disruptions of the integrity of the elastic tissue architecture may be responsible for the increased incidence of hypertension with age.
en-copyright=
kn-copyright=
en-aut-name=LiuJing-Jie
en-aut-sei=Liu
en-aut-mei=Jing-Jie
kn-aut-name=劉晶潔
kn-aut-sei=劉
kn-aut-mei=晶潔
aut-affil-num=1
ORCID=
en-aut-name=OhtaniOsamu
en-aut-sei=Ohtani
en-aut-mei=Osamu
kn-aut-name=大谷修
kn-aut-sei=大谷
kn-aut-mei=修
aut-affil-num=2
ORCID=
en-aut-name=KiutaAkio
en-aut-sei=Kiuta
en-aut-mei=Akio
kn-aut-name=菊田彰夫
kn-aut-sei=菊田
kn-aut-mei=彰夫
aut-affil-num=3
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=大塚愛二
kn-aut-sei=大塚
kn-aut-mei=愛二
aut-affil-num=4
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=田口勇仁
kn-aut-sei=田口
kn-aut-mei=勇仁
aut-affil-num=5
ORCID=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=村上宅郎
kn-aut-sei=村上
kn-aut-mei=宅郎
aut-affil-num=6
ORCID=
en-aut-name=SanoTadashi
en-aut-sei=Sano
en-aut-mei=Tadashi
kn-aut-name=佐能正
kn-aut-sei=佐能
kn-aut-mei=正
aut-affil-num=7
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=6
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=7
en-affil=
kn-affil=医療法人社団光生病院
en-keyword=aorta
kn-keyword=aorta
en-keyword=elastic tissue
kn-keyword=elastic tissue
en-keyword=scanning electron microscopy
kn-keyword=scanning electron microscopy
en-keyword=human
kn-keyword=human
en-keyword=rabbit
kn-keyword=rabbit
END
start-ver=1.4
cd-journal=joma
no-vol=105
cd-vols=
no-issue=1-2
article-no=
start-page=49
end-page=53
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1993
dt-pub=19930227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Central nervous cells with strongly negatively-charged surface-coats
kn-title=強陰性荷電被膜をもつ中枢神経細胞
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Light microscopy of tissue sections stained with cationic iron colloid (pH 1.0-2.0) and nuclear fast red or with this colloid and thionin revealed the presence of numerous neurons with a strong negative-charge or coated with sulfated proteoglycans such as chondroitin sulfates in the adult rat brain. These neurons were distributed mainly in the hippocampal subiculum, zona incerta, cerebral cortex (V lamina), medical cerebellar nuclei and certain other nuclei such as ventral pontine nuclei. In the hippocampal formation, the strongly negatively-charged cells seemed to be identical with the GABAergic inhibitory interneurons reactive to the lectin Vicia villosa agglutinin. The neurons, including the GABAergic Purkinje's cells, of the cerebellar cortex showed no reaction to the cationic iron colloid at pH 1.0-2.0. Many non-GABAergic large neurons of the ventral pontine nuclei were well reactive to the colloid at pH 1.0-2.0. These findings suggest that the cationic iron colloid at pH 1.0-2.0 mainly stains some subsets of GABA-ergic neurons, and additionally stains some non-GABAergic interneurons projecting long association or commissural fibers.
en-copyright=
kn-copyright=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=村上宅郎
kn-aut-sei=村上
kn-aut-mei=宅郎
aut-affil-num=1
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=田口勇仁
kn-aut-sei=田口
kn-aut-mei=勇仁
aut-affil-num=2
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=大塚愛二
kn-aut-sei=大塚
kn-aut-mei=愛二
aut-affil-num=3
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
en-keyword=Cationic iron colloid staining
kn-keyword=Cationic iron colloid staining
en-keyword=central nervous system
kn-keyword=central nervous system
en-keyword=neurons
kn-keyword=neurons
en-keyword=sulfated proteoglycans
kn-keyword=sulfated proteoglycans
END
start-ver=1.4
cd-journal=joma
no-vol=108
cd-vols=
no-issue=3-6
article-no=
start-page=145
end-page=148
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1996
dt-pub=19960629
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Artery ascending between the scalenus anterior and medius muscles. Accessory ascending cervical artery
kn-title=斜角筋隙を上行する動脈―副上行頚動脈
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Dissection of 25 adult Japanese cadavers revealed an artery that consistently arose from the subclavian artery and ascended between the scalenus anterior and medius muscles. This accessory ascending cervical artery, when developed, issued the dorsal scapular artery which penetrated the scalenus medius muscle. Typological discussion suggested that the accessory ascending cervical artery was a remnant of the longitudinal anastomoses along the embryonic intersegmental arteries.
en-copyright=
kn-copyright=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=村上宅郎
kn-aut-sei=村上
kn-aut-mei=宅郎
aut-affil-num=1
ORCID=
en-aut-name=HitomiSayoko
en-aut-sei=Hitomi
en-aut-mei=Sayoko
kn-aut-name=人見さよ子
kn-aut-sei=人見
kn-aut-mei=さよ子
aut-affil-num=2
ORCID=
en-aut-name=SatoTohru
en-aut-sei=Sato
en-aut-mei=Tohru
kn-aut-name=佐藤徹
kn-aut-sei=佐藤
kn-aut-mei=徹
aut-affil-num=3
ORCID=
en-aut-name=PiaoDa Xun
en-aut-sei=Piao
en-aut-mei=Da Xun
kn-aut-name=朴大
kn-aut-sei=朴
kn-aut-mei=大
aut-affil-num=4
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=大塚愛二
kn-aut-sei=大塚
kn-aut-mei=愛二
aut-affil-num=5
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=田口勇仁
kn-aut-sei=田口
kn-aut-mei=勇仁
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
affil-num=6
en-affil=
kn-affil=岡山大学医学部第二解剖学教室
en-keyword=Accessory ascending cervical artery
kn-keyword=Accessory ascending cervical artery
en-keyword=dorsal scapular artery
kn-keyword=dorsal scapular artery
en-keyword=vertebral artery
kn-keyword=vertebral artery
en-keyword=subclavian artery
kn-keyword=subclavian artery
en-keyword=intersegmental artery
kn-keyword=intersegmental artery
END
start-ver=1.4
cd-journal=joma
no-vol=113
cd-vols=
no-issue=1
article-no=
start-page=27
end-page=31
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2001
dt-pub=20010428
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A typical highest thoracic artery (A. thoracica suprema) -a case report-
kn-title=最上胸動脈，典型的と思われる1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A typical higest thoracic artery with anterior, posterior, ascending and descending branches was reported. Discussion suggests that this artery, when developed, gives rise to the internal thoracic artery descening lateral to the scalenus anterior muscle, transverse cervical artery, descending scapular artery, lateral thoracic artery or subscapular artery.
en-copyright=
kn-copyright=
en-aut-name=MurakamiShinichirou
en-aut-sei=Murakami
en-aut-mei=Shinichirou
kn-aut-name=村上慎一郎
kn-aut-sei=村上
kn-aut-mei=慎一郎
aut-affil-num=1
ORCID=
en-aut-name=MatsuokaHiroaki
en-aut-sei=Matsuoka
en-aut-mei=Hiroaki
kn-aut-name=松岡宏明
kn-aut-sei=松岡
kn-aut-mei=宏明
aut-affil-num=2
ORCID=
en-aut-name=FuyamaYasuhiro
en-aut-sei=Fuyama
en-aut-mei=Yasuhiro
kn-aut-name=普山康弘
kn-aut-sei=普山
kn-aut-mei=康弘
aut-affil-num=3
ORCID=
en-aut-name=TaguchiTakehito
en-aut-sei=Taguchi
en-aut-mei=Takehito
kn-aut-name=田口勇仁
kn-aut-sei=田口
kn-aut-mei=勇仁
aut-affil-num=4
ORCID=
en-aut-name=OhtsukaAiji
en-aut-sei=Ohtsuka
en-aut-mei=Aiji
kn-aut-name=大塚愛二
kn-aut-sei=大塚
kn-aut-mei=愛二
aut-affil-num=5
ORCID=
en-aut-name=MurakamiTakuro
en-aut-sei=Murakami
en-aut-mei=Takuro
kn-aut-name=村上宅郎
kn-aut-sei=村上
kn-aut-mei=宅郎
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部医学科解剖学第二講座
affil-num=2
en-affil=
kn-affil=岡山大学医学部医学科解剖学第三講座
affil-num=3
en-affil=
kn-affil=岡山大学医学部医学科解剖学第二講座
affil-num=4
en-affil=
kn-affil=岡山大学医学部保健学科放射線技術科学専攻
affil-num=5
en-affil=
kn-affil=岡山大学医学部医学科解剖学第二講座
affil-num=6
en-affil=
kn-affil=岡山大学医学部医学科解剖学第二講座
en-keyword=A. thoracia suprema
kn-keyword=A. thoracia suprema
en-keyword=A. transversa colli
kn-keyword=A. transversa colli
en-keyword=A. scapularis descendens
kn-keyword=A. scapularis descendens
en-keyword=A. thoracica lateralis
kn-keyword=A. thoracica lateralis
en-keyword=A. subscapularis
kn-keyword=A. subscapularis
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1986
dt-pub=19860930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=ラット頸動脈小体の血管構成,鋳型の走査電子顕微鏡観察
kn-title=Blood vascular organization of the rat carotid body. A scanning electron microscopic study of corrosion casts.
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=田口勇仁
kn-aut-sei=田口
kn-aut-mei=勇仁
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
END