start-ver=1.4 cd-journal=joma no-vol=39 cd-vols= no-issue=3 article-no= start-page=117 end-page=122 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Oral administration of the probiotic bacterium Lactobacillus acidophilus strain L-55 modulates the immunological parameters of the laying hen inoculated with a Newcastle disease virus-based live attenuated vaccine en-subtitle= kn-subtitle= en-abstract= kn-abstract=Probiotic supplements containing living bacteria have attracted interest as a potential source of health benefits for humans and livestock. The aim of this study was to determine whether administration of Lactobacillus acidophilus strain L-55 (LaL-55) enhances the immune response among chicks exposed to a Newcastle disease virus (NDV)-based live attenuated vaccine. Oral administration of LaL-55 augmented the elevation in the total numbers of leukocytes and lymphocytes following inoculation with the NDV-based live attenuated vaccine. Monocyte counts increased after LaL-55 administration independent of inoculation with the NDV vaccine. Among chicks that were administered LaL-55, there was a dose-dependent increase in the NK cell activity measured by a 51Cr release assay at 2 weeks after the secondary NDV vaccine inoculation. Two weeks after the secondary inoculation with the NDV vaccine, interferon (IFN)-γ-mRNA expression was significantly elevated in mononuclear splenocytes from chicks that were administered LaL-55. Meanwhile, LaL-55 administration did not change the mRNA levels of IFN-α, IFN-β, and interleukin-1β. These results may suggest that coadministration of LaL-55 with an NDV vaccine augments the immune response against the virus. Therefore, LaL-55 may help protect against viral diseases in poultry. en-copyright= kn-copyright= en-aut-name=HoDung Thi en-aut-sei=Ho en-aut-mei=Dung Thi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HatabuToshimitsu en-aut-sei=Hatabu en-aut-mei=Toshimitsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SunadaYosuke en-aut-sei=Sunada en-aut-mei=Yosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=3 en-affil=Research & Development, Ohayo Dairy Products Co., Ltd. kn-affil= affil-num=4 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= en-keyword=Lactobacillus acidophilus L-55 kn-keyword=Lactobacillus acidophilus L-55 en-keyword=chicken kn-keyword=chicken en-keyword=Newcastle disease vaccine kn-keyword=Newcastle disease vaccine en-keyword=immunomodulatory kn-keyword=immunomodulatory END start-ver=1.4 cd-journal=joma no-vol=43 cd-vols= no-issue=3 article-no= start-page=404 end-page=408 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200301 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Daily Meal Supplemented with Astaxanthin-Enriched Yolk Has Mitigative Effects against Hypertension in Spontaneously Hypertensive Rats en-subtitle= kn-subtitle= en-abstract= kn-abstract=The aim of this study was to investigate the effects of egg yolk powder enriched with astaxanthin (ASX-E) on blood pressure in spontaneously hypertensive rats (SHR) and to verify the benefits of ASX-E as a functional food. To investigate the antihypertensive effect, SHR were fed with an ASX-E mixed diet before hypertension development. Blood pressures were determined periodically during the study by the tail-cuff method. At the end of the study, animals were euthanized, and their thoracic aortas were collected to determine vascular conductance. The thoracic aorta tension was measured with a force displacement transducer. Concentration-dependent response relationships were determined by cumulative addition of 10−9–10−4 M Carbamoylcholine (Cch). Blood pressures of the SHR in the ASX-E mixed diet group were ASX-dose-dependently lower than that of those in the control group. In SHR fed with an ASX-E mixed diet, Cch induced vasorelaxation in the thoracic aorta with endothelium lining but not without endothelium. However, the antihypertensive effect of ASX-E was not observed on blood pressures in SHR that were fed with ASX-E only after the development of hypertension. Results suggest that ASX-E protects endothelial function and thereby prevents the development of hypertension. Hence, the results of our research indicate that daily consumption of ASX-E has a potential benefit on human health. en-copyright= kn-copyright= en-aut-name=HatabuToshimitsu en-aut-sei=Hatabu en-aut-mei=Toshimitsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HaradaTakumi en-aut-sei=Harada en-aut-mei=Takumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TakaoYuri en-aut-sei=Takao en-aut-mei=Yuri kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=DungHo Thi en-aut-sei=Dung en-aut-mei=Ho Thi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamasatoAkihiro en-aut-sei=Yamasato en-aut-mei=Akihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HoriuchiTatsuya en-aut-sei=Horiuchi en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MochizukiAtsuya en-aut-sei=Mochizuki en-aut-mei=Atsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Laboratory of Animal Physiology, Graduate School of Environmental and Life Science , Okayama University kn-affil= affil-num=2 en-affil=Laboratory of Animal Physiology, Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=3 en-affil=Laboratory of Animal Physiology, Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=4 en-affil=Laboratory of Animal Physiology, Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=5 en-affil=K.I Chemical Industry Co., Ltd. kn-affil= affil-num=6 en-affil=K.I Chemical Industry Co., Ltd. kn-affil= affil-num=7 en-affil=K.I Chemical Industry Co., Ltd. kn-affil= affil-num=8 en-affil=Laboratory of Animal Physiology, Graduate School of Environmental and Life Science, Okayama University kn-affil= en-keyword=astaxanthin-enriched egg yolk kn-keyword=astaxanthin-enriched egg yolk en-keyword=hypertension kn-keyword=hypertension en-keyword=spontaneously hypertensive rat kn-keyword=spontaneously hypertensive rat END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue= article-no= start-page=43 end-page=51 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of Sex-steroid Hormones on Lymphocyte Genesis in the Central Lymphoid Organs of Chickens kn-title=ニワトリのリンパ球造成と性ステロイドホルモン en-subtitle= kn-subtitle= en-abstract= kn-abstract=Lymphocytes play essential roles as a kind of leukocyte in the defense mechanism of animals against infectious factors. Lymphocytes are classified into two subsets, T lymphocytes and B lymphocytes in mammals or avian species. In avian species, T lymphocytes differentiate and proliferate in the thymus which is a central lymphoid organ common to mammalians and avian species, whereas on the other hand, B lymphocytes have been known to occur in the bursa of Fabricius (bursa) which is a unique central lymphoid organ of birds. Steroid hormones, such as androgen and estrogen, have been reported to change differentiations and proliferations of these lymphocytes in corresponding lymphoid organs, indicating steroid hormones give influence lymphocyte development positively or negatively in the bursa and thymus of birds. Studying the relation between steroid hormones and lymphocyte development in the central lymphoid organs is important, because changes in the lymphocyte genesis in central organs of birds may result in altered levels of antibody production and immune functions related to T lymphocyte activity. We have studied effects of androgen and estrogen on lymphocyte differentiation and proliferation in the central lymphoid organs of chicken at Okayama University since the 1980s. In the present report, the results of these studies are summarized. en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=lymphocyte kn-keyword=lymphocyte en-keyword=steroid hormone kn-keyword=steroid hormone en-keyword=bursa of Fabricius kn-keyword=bursa of Fabricius en-keyword=thymus kn-keyword=thymus END start-ver=1.4 cd-journal=joma no-vol=57 cd-vols= no-issue=1 article-no= start-page=45 end-page=48 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=200302 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Enhancement of norepinephrine-induced transient contraction in aortic smooth muscle of diabetic mice. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Changes in norepinephrine-induced transient contractions in Ca2+-deficient solution were investigated in the aortic smooth muscles of diabetic ALS (alloxan-induced diabetes susceptible) mice. The transient contractions in diabetic mice were significantly larger than those in normal mice. The longer incubation of the muscle preparations in Ca2+-deficient solution made the transient contractions smaller, probably due to the leakage and decrease in norepinephrine-releasable stored Ca2+. The rate of this reduction in contraction was slower in diabetic mice. These results suggest that the leakage of intracellular stored Ca2+ caused by extracellular Ca2+ deficiency is attenuated in diabetic mice, contributing to enhanced norepinephrine-induced transient contractions.

en-copyright= kn-copyright= en-aut-name=AbeAsaki en-aut-sei=Abe en-aut-mei=Asaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KawasoeChiaki en-aut-sei=Kawasoe en-aut-mei=Chiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoKatsunori en-aut-sei=Sato en-aut-mei=Katsunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=diabetes mellitus kn-keyword=diabetes mellitus en-keyword=vascular smooth muscle kn-keyword=vascular smooth muscle en-keyword=norepinephrine kn-keyword=norepinephrine END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=1 article-no= start-page=31 end-page=37 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=200902 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Animal Experiment on Functional Features of Eggs Stated to be Hypoallergenic for People with Food Allergies kn-title=低アレルギー発症性が言及されている鶏卵の機能特性に関する動物実験 en-subtitle= kn-subtitle= en-abstract=食物アレルギーを持つ消費者の経験に基づいて低アレルギー誘発性であることが言及されている鶏卵について，低アレルギー誘発性の有無と科学的な根拠を明らかにするために動物を用いた実験をおこなった．実験にはアレルギーを発症することが知られているラットの系統であるBrown Norway rat（BNラット）を用い，この鶏卵を混ぜ込んだ飼料で飼育した．対照として，市販の鶏卵（普通卵）で同様に飼育した．試験卵で飼育したBNラットでは，空腸と回腸組織のIgE陽性細胞の密度は普通卵で飼育した場合に比較して大きく低下した．組織中のIgE陽性細胞の大部分は肥満細胞であることが知られていることから試験卵群における小腸組織の肥満細胞密度は低下した．さらに，血中の好酸球数は同様に試験卵による飼育で低下した．一方，血清のIgE濃度には摂取させた卵による違いは認められなかった．以上の結果は，試験卵を摂取した場合，通常の卵の摂取に比較して即時型アレルギー症状の発生に直接的に関与する肥満細胞と好酸球の誘導や増殖が促進されにくいと考えられ，このことが，試験卵がアレルギーを引き起こしにくい一因であると推察される． kn-abstract=Functional features concerned with low proallergic natures were examined using an allergy-inducible rat strain (Brown Norway rat; BN rat) on hen's eggs which have been empirically mentioned as hypoallergenic for patients suffering from food allergies (experimental eggs). BN rats were fed on feed containing whole experimental eggs (feed E) and whole normal eggs (control feed, feed C). The densities of immunoglobulin E (IgE)-positive cells, have reported to be IgE-bearing mast cells, in the jejunum and ileum of BN rats fed on experimental-egg-containing feed were lower than those of BN rats fed on normal-egg-containing feed. The number of blood eosinophils was also lower in BN rats fed on feed E. Serum IgE levels were no different between BN rats fed on feed E and feed C. These results indicate that the low proallergic nature of hen's eggs studied in the present study is due to the dereased ability of experimental eggs to facilitate the proliferation and induction of mast cells in the intestinal tissue. en-copyright= kn-copyright= en-aut-name=NagatoKumiko en-aut-sei=Nagato en-aut-mei=Kumiko kn-aut-name=長門久美子 kn-aut-sei=長門 kn-aut-mei=久美子 aut-affil-num=1 ORCID= en-aut-name=AbeAsaki en-aut-sei=Abe en-aut-mei=Asaki kn-aut-name=阿部浅樹 kn-aut-sei=阿部 kn-aut-mei=浅樹 aut-affil-num=2 ORCID= en-aut-name=NarabaraKiyoaki en-aut-sei=Narabara en-aut-mei=Kiyoaki kn-aut-name=楢原清顕 kn-aut-sei=楢原 kn-aut-mei=清顕 aut-affil-num=3 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=応用動物科学コース affil-num=2 en-affil= kn-affil=応用動物科学コース affil-num=3 en-affil= kn-affil=応用動物科学コース affil-num=4 en-affil= kn-affil=応用動物科学コース en-keyword=egg kn-keyword=egg en-keyword=food allergy kn-keyword=food allergy en-keyword=IgE kn-keyword=IgE en-keyword=mast cells kn-keyword=mast cells END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=1 article-no= start-page=59 end-page=62 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cattle Performance Improvement Trials in Southeast Asian Countries, Using Japanese Cattle kn-title=東南アジア諸国の牛の日本の牛による改良の試み en-subtitle= kn-subtitle= en-abstract=この研究は日本の牛を用いて東南アジヤの牛の能力を改善するために計画した。日本の褐毛和種牛の凍結精液をインドネシア・北スラウエシのマナドに空輸した。この凍結精液をP.Ongole雌牛に人工授精した。289日の妊娠期間の後に1頭の雌雑種牛F1が生まれた。F1は日本の褐毛和種とオンゴール牛との間に生まれた最初の交雑種F1である。私どもはこれをジャブラゴール(Jabragole)と名付けた。 kn-abstract=The Project was designed to improve the performance of cattle in Southeast Asia, using Japanese Cattle, Frozen semen of the Japanese Brown breed of cattle was send by air to Manado, North sulawesi, lndonesia. The frozen semen was inseminated to P. O. (Peranakan Ongole) cow. A female hybrid (F1) was produced after duration of pregnancy of 289 days. This is the first hybrid of cattle between Japanese Brown breed cattle and Peranakan Ongole in lndonesia. We call F1 of crossbreed of Ongole with Japanese Brown breed cattle, Jabragole. en-copyright= kn-copyright= en-aut-name=WadaHiroshi en-aut-sei=Wada en-aut-mei=Hiroshi kn-aut-name=和田宏 kn-aut-sei=和田 kn-aut-mei=宏 aut-affil-num=1 ORCID= en-aut-name=TanakaKazue en-aut-sei=Tanaka en-aut-mei=Kazue kn-aut-name=田中一栄 kn-aut-sei=田中 kn-aut-mei=一栄 aut-affil-num=2 ORCID= en-aut-name=OkushimaShiroh en-aut-sei=Okushima en-aut-mei=Shiroh kn-aut-name=奥島史朗 kn-aut-sei=奥島 kn-aut-mei=史朗 aut-affil-num=3 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=4 ORCID= en-aut-name=KawamotoYasuo en-aut-sei=Kawamoto en-aut-mei=Yasuo kn-aut-name=河本泰生 kn-aut-sei=河本 kn-aut-mei=泰生 aut-affil-num=5 ORCID= en-aut-name=LantugL.A. en-aut-sei=Lantug en-aut-mei=L.A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MarangkeyJ.B. en-aut-sei=Marangkey en-aut-mei=J.B. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=東京農業大学家畜育種学講座 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 affil-num=6 en-affil= kn-affil=Section of Animal Husbandry, Distinct Office, North Sulawesi affil-num=7 en-affil= kn-affil=Animal Science, Samu Ratulangi University en-keyword=Ongole kn-keyword=Ongole en-keyword=Japanese Brown breed cattle kn-keyword=Japanese Brown breed cattle en-keyword=frozen semen kn-keyword=frozen semen en-keyword=hybrid kn-keyword=hybrid en-keyword=Jabragole kn-keyword=Jabragole END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=1 article-no= start-page=45 end-page=49 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=200402 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Induction of Atherosclerosis in Aorta and Coronary Artery of Chicken by Orally Administered Cholesterol kn-title=コレステロール負荷によって発症したニワトリ胸部大動脈と冠状動脈における動脈硬化症 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Hypercholesterolemia and hyperlipidemia have been important in human health as factors that induce atherosclerotic lesions in brain and heart blood vessel. Various experimental studies have been done to prevent and treat atherosclerotic lesions in animals. In the present study, we assessed the suitability of chickens as experimental animal for atherosclerosis. Newly hatched chicks were fed on 1.0%-or 0.1%-cholesterol(CHO) containing feed. After 3 and 6 months, total cholesterol levels in the sera and histological changes in the aorta and coronary artery of chicks fed on 1.0%-CHO-containing feed for 3 and 6 months, intimal thickening and marked accumulation of foam cells were observed. Endothelial cells had disappeared in the aorta of these chicks. A slight accumulation of foam cells was observed in the aortic intima of chicks fed on 0.1%-CHO-containing feed. In the coronary artery, a remarkable thickening of intima with accumulation of foam cells and a marked stenosis of coronary space were observed in chicks fed on 1.0%-CHO-containing feed. The results of present study indicate that the chicken can be a useful experimental animal in the study of hypercholesterolemia, hyperlipidemia and atherosclerosis. en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= en-aut-name=HonjoSachika en-aut-sei=Honjo en-aut-mei=Sachika kn-aut-name=本條幸香 kn-aut-sei=本條 kn-aut-mei=幸香 aut-affil-num=2 ORCID= en-aut-name=OhtsukiKazumasa en-aut-sei=Ohtsuki en-aut-mei=Kazumasa kn-aut-name=大月寿栄 kn-aut-sei=大月 kn-aut-mei=寿栄 aut-affil-num=3 ORCID= en-aut-name=AbeAsaki en-aut-sei=Abe en-aut-mei=Asaki kn-aut-name=阿部浅樹 kn-aut-sei=阿部 kn-aut-mei=浅樹 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 en-keyword=experimental atherosclerosis kn-keyword=experimental atherosclerosis en-keyword=cholrsterol kn-keyword=cholrsterol en-keyword=chicks kn-keyword=chicks END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=1 article-no= start-page=55 end-page=58 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200702 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ニワトリ胚のファブリシウス嚢におけるＢリンパ球の発達に対する sIgM 誘導因子の役割 kn-title=Role of the Surface IgM-Inducing Factor in Development of B Lymphocytes in Chicken Embryonic Bursa of Fabricius en-subtitle= kn-subtitle= en-abstract=ファブリシウス嚢はＢリンパ球分化と増殖のための中枢リンパ組織として鳥類の免疫機能の発達において重要な役割を演じている．培養ファブリシウス嚢上皮細胞は胚のファブリシウス嚢リンパ球に膜の IgM 分子（sIgM）の発 現を誘導する因子を産生することが報告されている．ファブリシウス嚢リンパ球の sIgM 発現誘導因子に対する感受性はファブリシウス嚢における分化の時期において変動する可能性が考えられる．ニワトリの胚では，リンパ球系の前駆細胞は胚発達の７日目から14日目の間においてのみファブリシウス嚢に進入・定着することが知られている．そこで本研究では，リンパ球系前駆細胞がファブリシウス嚢に定着するこの時期（10日胚から13日胚）におけるファブリシウス嚢リンパ球の sIgM 発現の変動を調べるとともに，これらの細胞における sIgM 発現誘導因子に対する感受性の変動について測定した．sIgM 陽性細胞の割合は11日胚で有意に上昇した．sIgM 発現誘導因子に対する反応性はこの時期の胚発達に伴って変動し，11日胚で高い傾向を示した．これらの結果から，11日胚齢はニワトリ胚のファブリシウス嚢におけるＢリンパ球の発達に関して重要な時期であることが示唆された． kn-abstract=　The bursa of Fabricius plays essential roles in the establishment of immune functions of avian species as a primary site for differentiation and proliferation of B lymphocytes. The bursa of chick embryos is colonized by lymphoid cell precursors only between the days 7th of embryogenesis (E7) and E14. Susceptibility to the sIgM-inducing factor may fluctuate in bursal lymphoid cells during the lymphoid precursor cell-receptive period. In the present study, the dynamic changes in the sIgM-positive ratio and responsiveness to sIgM-inducing factor were examined in lymphoid cells sampled from the bursa during the B precursor cell-receptive period (E10 to E13) and findings suggest that responsiveness to sIgM-inducing factor varies with the development of the chick embryos. E11 is suggested to be a critical stage of B-lymphocytegenesis in the bursa of chick embryos. en-copyright= kn-copyright= en-aut-name=HanSong en-aut-sei=Han en-aut-mei=Song kn-aut-name=韓松 kn-aut-sei=韓 kn-aut-mei=松 aut-affil-num=1 ORCID= en-aut-name=AbeAsaki en-aut-sei=Abe en-aut-mei=Asaki kn-aut-name=阿部浅樹 kn-aut-sei=阿部 kn-aut-mei=浅樹 aut-affil-num=2 ORCID= en-aut-name=NaraharaKiyoaki en-aut-sei=Narahara en-aut-mei=Kiyoaki kn-aut-name=楢原清顕 kn-aut-sei=楢原 kn-aut-mei=清顕 aut-affil-num=3 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 en-keyword=bursa of Fabricius kn-keyword=bursa of Fabricius en-keyword=B lymphocytegenesis kn-keyword=B lymphocytegenesis en-keyword=sIgM-inducing factor kn-keyword=sIgM-inducing factor END start-ver=1.4 cd-journal=joma no-vol=77 cd-vols= no-issue=1 article-no= start-page=1 end-page=8 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Selective Accumulation of Some Leaf Xanthophylls in Hen Egg Yolk and Its Manner. kn-title=緑葉カロテノイドのニワトリ卵黄への選択的移行とその機構 en-subtitle= kn-subtitle= en-abstract= kn-abstract=ニワトリにおける緑葉カロテノイドの吸収と体組織分布について部分的に明らかにするとともに,とくに卵黄へのルテインの集中選択的蓄積に関する知見を得た. 投与した緑葉カロテノイド各々のみかけ吸収率は50～65%とカロテノイドによる差は認められないが,卵黄への蓄積量及び蓄積率はキサントフィルが高く,なかでもルテインはそのみかけ吸収量の25%が卵黄に蓄積している.これに対し,β－カロチンはみかけ吸収量のわずか0.6%しか蓄積せず,卵黄全カロテノイドに占める割合もルテインの約85%に対し1%である. 3日間の短期投与による緑葉カロテノイドの肝,卵巣,血液への正味蓄積量において,ルテインは肝よりも卵巣に6倍以上の速度で蓄積するのに対し,他のキサントフィル及びβ－カロテンは肝に多く蓄積する傾向がある.このことは緑葉カロテノイドのうちルテインがとくに卵黄に蓄積しやすいことを示すものである。 en-copyright= kn-copyright= en-aut-name=TakagiShigeaki en-aut-sei=Takagi en-aut-mei=Shigeaki kn-aut-name=高木茂明 kn-aut-sei=高木 kn-aut-mei=茂明 aut-affil-num=1 ORCID= en-aut-name=NakanoHiroyuki en-aut-sei=Nakano en-aut-mei=Hiroyuki kn-aut-name=中野浩行 kn-aut-sei=中野 kn-aut-mei=浩行 aut-affil-num=2 ORCID= en-aut-name=KimuraYoshinobu en-aut-sei=Kimura en-aut-mei=Yoshinobu kn-aut-name=木村吉伸 kn-aut-sei=木村 kn-aut-mei=吉伸 aut-affil-num=3 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=4 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 en-keyword=緑葉カロテノイド kn-keyword=緑葉カロテノイド en-keyword=ニワトリ卵黄 kn-keyword=ニワトリ卵黄 en-keyword=ルテイン kn-keyword=ルテイン END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=1 article-no= start-page=19 end-page=22 dt-received= dt-revised= dt-accepted= dt-pub-year=1987 dt-pub=1987 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Chlamydial Complement Fixing Antibodies in Feral Pigeons kn-title=ドバト集団におけるクラミジア抗体保有率 en-subtitle= kn-subtitle= en-abstract= kn-abstract=名古屋市内及び周辺の3地区(市街地,住宅地及び近郊農村地区)並びに東京の1地区(繁華街)の計4ドバト集団について,クラミジア(CF)抗体保有状況を陽性率と抗体力価の面から調査した.1984年に採取した集団別の材料では,抗体力価は住宅地や農村部よりも市街地で高い傾向にあったが,陽性率においては集団間の差は小さかった.名古屋市街地における1984年から1986年の3年間にわたる調査では,陽性率は急激に上昇していることが明らかとなった.以上の結果について,今までの報告と比較検討した。 en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= en-aut-name=TosaKaori en-aut-sei=Tosa en-aut-mei=Kaori kn-aut-name=土左かおり kn-aut-sei=土左 kn-aut-mei=かおり aut-affil-num=2 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=3 ORCID= en-aut-name=SotoKoji en-aut-sei=Soto en-aut-mei=Koji kn-aut-name=佐藤孝二 kn-aut-sei=佐藤 kn-aut-mei=孝二 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=名古屋大学農学部 END start-ver=1.4 cd-journal=joma no-vol=64 cd-vols= no-issue=1 article-no= start-page=53 end-page=59 dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=1984 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ontogeny and Age Distribution of Specific Antigens and Surface Immunoglobulins on the Lymphocyte Membranes of Chick Embryos kn-title=ニワトリ胚におけるリンパ球の膜特異抗原と膜表面Igの発生と成長に伴う変動 en-subtitle= kn-subtitle= en-abstract= kn-abstract=鶏の胚の胸腺,BF及び脾臓中のT+リンパ球,B+リンパ球,sIg+リンパ球及びsIgM+リンパ球の比率の加齢に伴う変化を経時的に追求した. 胸腺では,胚齢11日目にT+リンパ球及びB+リンパ球が,胚齢12日目にｓIg+リンパ球及びsIgM+リンパ球が発生した. 一方BFでは,胚齢10日目にT+リンパ球が,胚齢11日目にB+リンパ球,sIg+リンパ球及びsIgM+リンパ球が発生した. 胸腺では,胚齢15日目からT+リンパ球の比率が,一方BFでは胚齢17日目からB+リンパ球の比率が急激に上昇することから,この時点より真の分化が始まると考えられる. BFでは,ｓIg+リンパ球及びsIgM+リンパ球が胚齢11日目に発生してから胚齢16日目まで,ほぼ同じ値で推移していることから,胚齢16日目までBリンパ球のsIgはIgMのみであると考えられる. BFでは,胚齢16日目以降,sIg+リンパ球の比率がsIgM+リンパ球の比率を大幅に上回ることから,胚齢16日目前後に,Bリンパ球のsIgでは,IgMから他のクラスのlgへの転換(スイッチ)が始まると考えられる。 en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= en-aut-name=AriyasuToshio en-aut-sei=Ariyasu en-aut-mei=Toshio kn-aut-name=有安利夫 kn-aut-sei=有安 kn-aut-mei=利夫 aut-affil-num=2 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=3 ORCID= en-aut-name=ToriumiTooru en-aut-sei=Toriumi en-aut-mei=Tooru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=63 cd-vols= no-issue=1 article-no= start-page=27 end-page=33 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=1983 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effect of Starvation on Immunological Function of Chicks : I. Effect on Humoral Immunity kn-title=ニワトリの免疫機能に及ぼす飢餓の影響 I.液性免疫機能に及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=隔日絶食による長期間の飢餓状態におけるニワトリヒナのGRBC及びBAに対する抗体産生能力を調べることにより,液性免疫機能に及ぼす飢餓の影響について試験した. 本試験において得られた結果は以下のようである. (1)絶食期間中,ヒナの体重増加はまったく認められず,強度の飢餓状態にあると思われた. (2)飢餓状態にあるヒナでは,抗GRBC,抗BA共に抗体価が上昇する傾向が示された. (3)血中のγ－グロブリン総量及び産生された抗体中のIgM比率については,対照との間に差が認められなかった. (4)飢餓状態のヒナにより産生される抗GRBC抗体の半減期は,対照に比べ有意に長いことが示された. 以上の結果から,長期にわたる飢餓にさらされたヒナでは,産生される抗体の血中からの消退が遅延し,その結果,抗体価が上昇するものと思われた. これは,抗体産生の亢進によるものではなく,産生された抗体の分解遅延に起因するものと思われた。 en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= en-aut-name=TaniguchiYoshihiro en-aut-sei=Taniguchi en-aut-mei=Yoshihiro kn-aut-name=谷口吉弘 kn-aut-sei=谷口 kn-aut-mei=吉弘 aut-affil-num=2 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=3 ORCID= en-aut-name=ToriumiTooru en-aut-sei=Toriumi en-aut-mei=Tooru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=62 cd-vols= no-issue=1 article-no= start-page=19 end-page=23 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=1983 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Distribution of Membrane Antigen and Immunoglobulin Positive Lymphocytes in the Lymphoid Organs of Chicks kn-title=ニワトリヒナのリンパ組織におけるB抗原陽性リンパ球とIg陽性リンパ球の分布 en-subtitle= kn-subtitle= en-abstract= kn-abstract=ニワトリのファブリシウス嚢,胸腺および脾臓リンパ球中のB抗原陽性リンパ球,T抗原陽性リンパ球及びIg陽性リンパ球比率の加令に伴う変化を経時的に追求した. B抗原陽性率はBFリンパ球で,T抗原陽性率は胸腺リンパ球においてそれぞれ高率に認められたが,週令が増すに従い減少する傾向を示した. BFリンパ球ではB抗原を持つがIgを持たないBリンパ球が存在する一方,脾臓Bリンパ球のすべてはB抗原と膜Igの両方を持つことから,Bリンパ球の分化過程において,B抗原は膜Igよりも早期に現れることが推察された. 膜抗原の存在率から,BFと胸腺のリンパ球内には,膜抗原マーカーを持たないnull cellがかなり多く存在していると考えられた。 en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=2 ORCID= en-aut-name=ToriumiTooru en-aut-sei=Toriumi en-aut-mei=Tooru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=62 cd-vols= no-issue=1 article-no= start-page=13 end-page=18 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=1983 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Pharmacokinetics of Arsenic Compound in the Chicken : I. Distribution, Excretion and Transference to the Eggs of Arsenic Administered Orally to Chickens. kn-title=ヒ素化合物のニワトリ体内動態に関する研究 I.経口投与された3酸化ヒ素の体内分布、排泄及び卵への移行 en-subtitle= kn-subtitle= en-abstract= kn-abstract=1.3酸化ヒ素30mg/㎏を産卵鶏に経口投与して,1,2,4,8,16および32日めの各臓器,組織及び卵中のヒ素濃度をしらべた. 又雄鶏に人工肛門手術を施し,3酸化ヒ素30mg/㎏を経口投与して,以後排泄される尿と糞のヒ素量をしらべた. 2.検査した諸臓器のうちヒ素移行率の高かったのは肝,腎,心筋であった. 血漿と脾では中程度の分布率であり,赤血球,浅胸筋および脳組織の移行率は低かった. 又ヒ素のリテンションの長かったのは肝,腎,脾,浅胸筋であり,特に肝では32日めにも対照の水準に復しなかった. 3.卵ではヒ素は主として卵黄に移行し,卵白には極めて低濃度にしか移行しなかった. 4.人工肛門手術を受けたニワトリの尿中には投与後6時間めまでにヒ素が出現し始め,3日めまで急増して最高値となり,以後は一定の率で漸減した,一方糞中には投与後6～18時間でヒ素が出現し始め,36～48時間めまで急増して最高値となり,以後11日めまで緩やかに減少し,それ以後は急減した. 17日めまでに排泄されたヒ素の総量は尿中に投与量の15%,糞中に20%であった。 en-copyright= kn-copyright= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=1 ORCID= en-aut-name=YunokiMasashi en-aut-sei=Yunoki en-aut-mei=Masashi kn-aut-name=柚木正志 kn-aut-sei=柚木 kn-aut-mei=正志 aut-affil-num=2 ORCID= en-aut-name=NoguchiShigeaki en-aut-sei=Noguchi en-aut-mei=Shigeaki kn-aut-name=野口重明 kn-aut-sei=野口 kn-aut-mei=重明 aut-affil-num=3 ORCID= en-aut-name=ToriumiTooru en-aut-sei=Toriumi en-aut-mei=Tooru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=4 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=1 article-no= start-page=7 end-page=13 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=1980 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Effect of Testosterone and Other Steroid Hormones on the Tumor Lymphocyte Lines Isolated from Chickens kn-title=リンパ腫症及びマレック病腫瘍細胞に対するテストステロンほか各種ステロイドホルモンの結果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=ニワトリのマレック病およびリンパ腫症の腫瘍リンパ球増殖に及ぼすテストステロンほか各種ステロイドホルモンの効果ならびに3H－テストステロンに対するそれらの細胞の結合量を調べた. さらに,正常リンパ球におけるテストステロンの効果およびその結合量を調べた. テストステロンのほか,エストロジェンおよびグルココルチコイドにおいて,両腫瘍細胞あるいは一方の腫瘍細胞に対する増殖抑制効果が観察された. 正常リンパ球では,テストステロンは,Bリンパ球の生存率を減少させたが,Tリンパ球に対する効果はなかった. 3H－テストステロンに対する結合量は,腫瘍細胞では多量で,Bリンパ球でも比較的多かったが,Tリンパ球では少なかった. 以上の結果から,腫瘍細胞を含めたリンパ球におけるステロイドホルモンの効果は,多量のステロイドホルモンが細胞に結合することに基づくものと結論された. さらに,リンパ球の分化に関して,Tリンパ球は成熟のある時期にテストステロンに対する感受性を失なう一方,Bリンパ球は､その感受性を保持し続けることが示唆された。 en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= en-aut-name=ShiotaMasahiko en-aut-sei=Shiota en-aut-mei=Masahiko kn-aut-name=塩田雅彦 kn-aut-sei=塩田 kn-aut-mei=雅彦 aut-affil-num=2 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=3 ORCID= en-aut-name=ToriumiTooru en-aut-sei=Toriumi en-aut-mei=Tooru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=4 ORCID= en-aut-name=SatoKoji en-aut-sei=Sato en-aut-mei=Koji kn-aut-name=佐藤孝二 kn-aut-sei=佐藤 kn-aut-mei=孝二 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=名古屋大学農学部 END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue=1 article-no= start-page=55 end-page=60 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=1978 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ニワトリの神経におけるCholinesteraseの軸索内移動 kn-title=The Axoplasmic Transport of Cholinesterases in Chicken Nerves en-subtitle= kn-subtitle= en-abstract= kn-abstract=1. The axoplasmic transport of cholinesterases was investigated in chicken vagus and sciatic nerve trunks by the ligature method. 2. Even 48 hours after ligation, the nerve segments in which the increased activity of acetylcholinesterase (AChE) was observed were ristricted within 5mm from the ligature. The activity of AChE in these segments increased linearly until 24 hours or 48 hours after ligation. 3. Two ligatures were made on sciatic nerve trunks and the change in activity of AChE between them was investigated. And it was found that only about 13% of AChE was moved by fast flow. The velocity was 233. 8mm/day in the anterograde and 97.7mm/day in the retrograde direction. 4. The activity of pseudo-cholinesterase (Ps-ChE) also accumulated with time at the proximal and distal side of the ligature. en-copyright= kn-copyright= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=1 ORCID= en-aut-name=TajiriShinsuke en-aut-sei=Tajiri en-aut-mei=Shinsuke kn-aut-name=田尻新介 kn-aut-sei=田尻 kn-aut-mei=新介 aut-affil-num=2 ORCID= en-aut-name=MatsumotoIsao en-aut-sei=Matsumoto en-aut-mei=Isao kn-aut-name=松本功 kn-aut-sei=松本 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=4 ORCID= en-aut-name=ToriumiTooru en-aut-sei=Toriumi en-aut-mei=Tooru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue=1 article-no= start-page=49 end-page=53 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=1978 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Prevention of Leucitytozoon Infection of the Chicken : VIII. Preventive Effects of Sulfamonomethoxine and Halofuginone kn-title=ニワトリのLeucocytozoon病の予防に関する研究 VIII. Sulfamonomethoxine ならびに Halofuginone の感染予防効果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=SMならびにHFについて,これらを飼料中に添加運続投与した場合本病の自然感染予防効果について試験を行なった. 1.SMは12.5ppm添加ではparasitemiaならびに抗体産生はそれぞれ26.7%,76.7%の個体に認められ感染予防効果はないものと考えられた. しかし50ppm添加区ではparasitemiaの認められたもの0%,抗体陽性となったもの31.0%であり,感染は予防し,かつ免疫も付与するという現象が認められた. 2.HFの3ppmおよび6ppm添加の場合はともにほぼ完全にparasitemiaならびに抗体産生を阻止し,予防効果のあることを示した. 3.HFの6ppm添加の場合は雄の群において,飼料摂取量の低下に原因する増体量の低下が認められた。 en-copyright= kn-copyright= en-aut-name=ToriumiTohru en-aut-sei=Toriumi en-aut-mei=Tohru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=1 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=2 ORCID= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=3 ORCID= en-aut-name=YamaguchiKohshi en-aut-sei=Yamaguchi en-aut-mei=Kohshi kn-aut-name=山口公士 kn-aut-sei=山口 kn-aut-mei=公士 aut-affil-num=4 ORCID= en-aut-name=YamadaYoshiaki en-aut-sei=Yamada en-aut-mei=Yoshiaki kn-aut-name=山田義昭 kn-aut-sei=山田 kn-aut-mei=義昭 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山県 affil-num=5 en-affil= kn-affil=岡山県 END