Author Ohta, Takeo|
Published Date 1999-12-20
Publication Title 岡山大学医学部保健学科紀要
Volume volume10
Issue issue1
Content Type Others
Author 岡山大学医療技術短期大学部|
Published Date 1991-03-25
Publication Title 岡山大学医療技術短期大学部紀要
Volume volume1
Content Type Others
Author 岡山大学医療技術短期大学部|
Published Date 1996-02-29
Publication Title 岡山大学医療技術短期大学部紀要
Volume volume6
Content Type Others
Author 岡山大学医療技術短期大学部|
Published Date 1993-01-31
Publication Title 岡山大学医療技術短期大学部紀要
Volume volume3
Content Type Others
Author 岡山大学農学部附属山陽圏フィールド科学センター|
Published Date 2005-12-01
Publication Title 岡山大学農学部センター報告
Volume volume27
Content Type Others
Author 吉野 熙道|
Published Date 2003-11-01
Publication Title 岡山大学農学部センター報告
Volume volume24
Content Type Others
Author 岡山大学農学部附属山陽圏フィールド科学センター|
Published Date 2005-12-01
Publication Title 岡山大学農学部センター報告
Volume volume27
Content Type Others
Author 岡山大学農学部附属山陽圏フィールド科学センター|
Published Date 2003-11-01
Publication Title 岡山大学農学部センター報告
Volume volume24
Content Type Others
Author Yoshii, Taishi|
Published Date 2015-06
Publication Title Okayama University Medical Research Updates
Volume volume12
Content Type Others
Author Bando, Tetsuya|
Published Date 2015-10
Publication Title Okayama University Medical Research Updates
Volume volume16
Content Type Others
Author 川本 克也|
Published Date 2015-02
Publication Title 環境制御
Volume volume36
Content Type Others
Author Ishikawa, Atsushi|
Published Date 2015-09
Publication Title Okayama University Medical Research Updates
Volume volume15
Content Type Others
Author Kawamoto, Katsuya|
Published Date 2016-02
Publication Title Environmental Research & Control
Volume volume37
Content Type Others
Author Ohara, Toshiaki| 櫻間 教文| 唐井 利昌|
Publication Title
Content Type Others
Title Alternative Contribution and progress of the gnotobiote technology in gut microbiome research
FullText URL poalas_033_011_014.pdf
Author Morita, Hidetoshi|
Publication Title Proceedings of Okayama Association for Laboratory Animal Science
Published Date 2017-04
Volume volume33
Start Page 11
End Page 14
language 日本語
File Version publisher
Author Watanabe, Mamoru| Tachibana, Hidenori|
Published Date 2006-03-31
Publication Title 岡山大学文学部プロジェクト研究報告書
Volume volume2006
Issue issue1
Content Type Others
Author Watanabe, Mamoru| Tachibana, Hidenori|
Published Date 2006-03-31
Publication Title 岡山大学文学部プロジェクト研究報告書
Volume volume2006
Issue issue1
Content Type Others
Author Shimizu, Kenji|
Published Date 1996-09
Publication Title 岡山実験動物研究会報
Volume volume13
Content Type Others
Author Takahashi, Sumio|
Published Date 1995-07
Publication Title 岡山実験動物研究会報
Volume volume12
Content Type Others
Title Alternative Transcription factor Runx3 in the mouse hypothalamo-pituitary-gonadal system
FullText URL poalas_034_002.pdf
Author Takahashi, Sumio|
Abstract Runx3 is a transcription factor that belongs to the Runx family. Female Runx3 knockout (Runx3−⁄−) mouse was anovulatory and infertile. Ovarian transplantation experiment suggested that lack of ovulation in Runx3−⁄− mice was caused by alteration of gonadotropin secretion in Runx3−⁄− mice. Cyp11a1 mRNA expression was less in Runx3−⁄− mouse ovaries than in wt ones. Hypothalamic Gnrh1 mRNA was increased, and Kiss1 mRNA expression in the anteroventral periventricular nucleus was decreased, but Kisspeptin mRNA in the arcuate nucleus was increased in Runx3-/- mice. Pituitary Fshb mRNA levels were increased in Runx3−⁄− mice. Cholesterol side-chain cleavage enzyme gene (Cyp11a1) expression was decreased in ovaries of Runx3−⁄− mice. These findings suggest that anovulation in Runx3−⁄− mice was partly due to the alterations in hypothalamus-pituitary-ovary system. Runx3 plays a key role in female reproduction through alteration of gonadotropin secretion.
Publication Title Proceedings of Okayama Association for Laboratory Animal Science
Published Date 2018-04
Volume volume34
Start Page 2
End Page 4
language 日本語
File Version publisher