ID | 56659 |
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Author |
Takamura, Hiroyoshi
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
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Abstract | A variety of natural products, a valuable source of drug lead compounds, coexist with their stereoisomers as congeners. For pursuing the structural elucidation and the structure–activity relationship study of natural products, it is needed to establish the streamlined synthetic route to supply natural products and their stereoisomers. Divergent pathway is one of the synthetic strategies to deliver more than one target compound. In this digest, selected examples of the stereodivergent approach toward the synthesis of natural products are described. Especially, this digest focuses on common synthetic intermediates and stereodiversification steps from the common intermediates to reach the target compounds.
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Keywords | Natural product
Stereodivergent synthesis
Stereodiversification
Stereoisomer
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Published Date | 2018-02-10
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Publication Title |
Tetrahedron Letters
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Volume | volume59
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Issue | issue11
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Publisher | Pergamon Press
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Start Page | 955
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End Page | 966
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ISSN | 00404039
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NCID | AA00861801
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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File Version | author
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Related Url | isVersionOf https://doi.org/10.1016/j.tetlet.2018.02.004
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