| ID | 56860 |
| JaLCDOI | |
| FullText URL | |
| Author |
Sakamoto, Shinji
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kawai, Hiroki
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Okahisa, Yuko
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Tsutsui, Ko
Department of Neuropsychiatry, Akita University Graduate School of Medicine
Kanbayashi, Takashi
Department of Neuropsychiatry, Akita University Graduate School of Medicine
Tanaka, Keiko
Department of Animal Model Development, Brain Research Institute, Niigata University
Mizuki, Yutaka
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Takaki, Manabu
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Yamada, Norihito
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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| Abstract | Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently-discovered autoimmune disorder in which antibodies target NMDAR in the brain. The number of reported cases of anti-NMDAR encephalitis has increased rapidly. Anti-NMDAR encephalitis can be mistakenly diagnosed as psychiatric disorders because many patients present with prominent psychiatric symptoms and visit psychiatric institutions first. Thus, psychiatrists should cultivate a better understanding of anti-NMDAR encephalitis. In this review, we present the mechanisms, epidemiology, symptoms and clinical course, diagnostic tests, treatment and outcomes of patients with anti-NMDAR encephalitis. Furthermore, we discuss the diversity of clinical spectra of anti-NMDAR encephalitis, and demonstrate a differential diagnosis of psychiatric disease from the perspective of psychiatry.
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| Keywords | NMDAR
encephalitis
psychiatric symptom
schizophrenia
mood disorder
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| Amo Type | Review
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| Publication Title |
Acta Medica Okayama
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| Published Date | 2019-06
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| Volume | volume73
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| Issue | issue3
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| Publisher | Okayama University Medical School
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| Start Page | 189
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| End Page | 195
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| ISSN | 0386-300X
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| NCID | AA00508441
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| Content Type |
Journal Article
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| language |
English
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| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School
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| File Version | publisher
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| Refereed |
True
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| PubMed ID |
