start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=表紙・目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=岡山大学溫泉研究所 kn-aut-sei=岡山大学溫泉研究所 kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=35 end-page=81 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=EFFECTS OF RADIO-ACTIVE THERMAL BATH ON OXIDATION- REDUCTION SYSTEM kn-title=放射能泉に関する研究(XXXI) 放射能泉入浴の酸化還元機轉に及ぼす影響(Ⅲ) 放射能泉入浴とビタミンC代謝 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author proved that consumption of iodate by proteinfree serum filtrate, an index of total reductive substance in serum filtrate, was increased after a radioactive thermal bath of Misasa (400-700×10(-10) Curie units Rn per liter), at a temperature of 40°~45℃ for five minutes. Reduced glutathion in blood showed little change, but oxidized and total glutathion tend to rise and decreased only temporarily. Reduced ascorbic acid in blood and urine increased after the radioactive thermal bath, but the oxidized and total ascorbic acid decreased after a temporal increase. After the thermal. bath a tendency of fall in reduced and oxidized ascorbic acid content was observed in liver, lung, and adrenal glands, and a tendency of rise was shown in kidney, spleen, skin and musclein albino rats. By a series of daily successive thermal baths a fall in ascorbic acid content was observed in most of the organs examined in the first week (on the fourth day) and then a reactive increase was shown during the second week. en-copyright= kn-copyright= en-aut-name=SotozonoMasazumi en-aut-sei=Sotozono en-aut-mei=Masazumi kn-aut-name=外園正純 kn-aut-sei=外園 kn-aut-mei=正純 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=26 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=放射能泉に関する研究(XXX) 放射能泉入浴の酸化還元機轉に及ぼす影響(Ⅱ) 放射能泉入浴の血液グルタチオンに及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=外園正純 kn-aut-sei=外園 kn-aut-mei=正純 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=20 end-page=25 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=MEDICAL STUDIES ON CHONDROITIN SULFATE (2nd Report) kn-title=コンドロイチン硫酸の医学的研究-2- en-subtitle= kn-subtitle= en-abstract= kn-abstract=After the internal use of daily 3 grams of crude chondroitin sulfate cholinesterase activity of serum decreased and elimination of glycuronic acid in urine increased, but no definite change in serum mucoprotein level was observed. Mucoprotein in serum showed a positive linear correlation to erythrocyte sedimentation rate, and chondroitin sulfate promoted the e.s.r. in vitro and in vivo. Chondroitin sulfate showed no marked influence on phagocytosis of human leucocytes in vitro, but it promoted the production of agglutinin in rabbits by subcutaneous injection. en-copyright= kn-copyright= en-aut-name=OshimaYoshio en-aut-sei=Oshima en-aut-mei=Yoshio kn-aut-name=大島良雄 kn-aut-sei=大島 kn-aut-mei=良雄 aut-affil-num=1 ORCID= en-aut-name=YokotaTakeo en-aut-sei=Yokota en-aut-mei=Takeo kn-aut-name=横田剛男 kn-aut-sei=横田 kn-aut-mei=剛男 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所内科 affil-num=2 en-affil= kn-affil=岡山大学温泉研究所内科 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=15 end-page=19 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=CHEMICAL STUDIES ON MISASA HOT SPRING (18) A PYRITE-POLYSULFIDE THEORY OF SULFUR SPRING kn-title=三朝温泉の化学的研究(18)-硫黄泉の成因に関する黄鉄鉱多硫化物説- en-subtitle= kn-subtitle= en-abstract= kn-abstract=In Misasa there occur only few weak sulfur springs, their maximum hydrogen sulfide content being about 5mg per liter. The ground of Misasa consists of granite and there is no active volcano in the vicinity. So the author tried to explain the mechanism of the occurrence of sulfur spring in Misasa by a reaction of the primarily alkaline thermal water upon pyrite. Namely: XFeS(2) + 3Na(2)C(O)3 = 2Na(2)S(1-5) + Na(2)S(2)O(3) + 3CO(2) + XFeS(1-2) Thiosulfate in sulfur spring waters should not be taken for a secondary product from hydrogen sulfide as accepted generally, but is most probably a primary product to the latter. The phenomenon of white turbidity in sulfur spring is caused mainly by the sulfur liberated from the polysulfide decomposed by the change in pH and temperture of thermal waters and not by the sulfur liberated from the oxidation of hydrogen sulfide. Some experimental data were shown to support the theory. en-copyright= kn-copyright= en-aut-name=AshizawaTakashi en-aut-sei=Ashizawa en-aut-mei=Takashi kn-aut-name=芦沢峻 kn-aut-sei=芦沢 kn-aut-mei=峻 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所化学部 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=12 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=FLUORINE CONTENT OF THERMAL WATERS IN TOTTORI PREFECTURE AND ITS RELATION TO MOTTLED TOOTH AND GOITER (2nd REPORT) kn-title=温泉のフッ素合有量と斑状歯並に甲状腺腫の関係-2- en-subtitle= kn-subtitle= en-abstract= kn-abstract=The fluorine content of 67 samples of mineral waters in Misasa, Asozu, Togo, Hamamura, and Iwai Hot Springs was investigated by Zirconium-Alizarine Sulfonate method. It ranged from 1.5 to 15 mg. per liter, 3-6mg. per liter in the majority. Most of the river and well waters in the same districts contained no measurable amount of fluorifle. In Misasa, Asozu, Togo and Hamamura Hot Springs 68-83 per cent of the schoolchildren who take thermal waters habitually as drinking water suffer from mottled tooth. On the contrary 2-10 per cent of the schoolchildren who do not drink thermal waters habitually showed mottled tooth. In Iwai no inhabitant uses thermal water as drinking water, so that the incidence of mottled tooth among them was only 2.8 per cent. Concerning the incidence of struma in the schoolchildren no relationship was proved between the occurrence of mottled tooth or fluorine content of thermal waters. en-copyright= kn-copyright= en-aut-name=OndaSakue en-aut-sei=Onda en-aut-mei=Sakue kn-aut-name=音田作衛 kn-aut-sei=音田 kn-aut-mei=作衛 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所内科 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=8 end-page=11 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=STUDIES ON THE EFFECTS BY PUMPING SUCTION OF HOT-SPRING kn-title=溫泉の吸引による結果に対する二、三の知見 en-subtitle= kn-subtitle= en-abstract= kn-abstract=At Sekigane Hot-Spring, Tottori, Japan, where three hot-springs place side by side, the auther measured the variation of spring temperature, pH, Cl,- HCO(3)- and SO (4)-- content and the amount of flow, during and after, pumping suction of one hot-spring. About the variation of other hot-spring, immediately after the commencement of suction, the content of HCO(3)- decreased and that of Cl- and SO(4)-- increased. Then the increase of HCO(3)- content and the decrease of Cl- and SO(4)--contents appeared with the lapse of time. After stopping the suction, these changes in contents were reversed agaln, that is, the decrease of HCO(3)- and the increage of Cl- and SO(4)-- were observed. Immediately after the second suction was begun, HCO(3)- increased and Cl- and SO(4)-- decreased rapidly. The amount of flow increased only when the pumping suction stopped. At the hot-spring which was pumped, HCO(3)- and SO(4)-- contents decreased and the slight increase was observed in Cl- content. Of cource, only when the suction stopped, the amount of flow decreased. But at these hot-springs, the ratio of Cl-/SO(4)-- has always constant value, about 1.05. These results show that these three hot-springs belong to the same line and difference was observed only in the contamination with ground-watres. en-copyright= kn-copyright= en-aut-name=UmemotoShunji en-aut-sei=Umemoto en-aut-mei=Shunji kn-aut-name=梅本春次 kn-aut-sei=梅本 kn-aut-mei=春次 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所化学部 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=6 end-page=7 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=RADON CONTENT OF MISASA HOT-SPRING, JAPAN en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=UmemotoShunji kn-aut-sei=Umemoto kn-aut-mei=Shunji aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=BALNEOLOGICAL LABORATORY, OKAYAMA UNIVERSITY END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue= article-no= start-page=1 end-page=5 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=195208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=BALNEOLOGICAL STUDIES USING RADIO-ACTIVE ISOTOPES (1) ON THE MECHANISM OF THE ACTION OF SODIUM SULFATE SPRING BATH. kn-title=人工放射性同位元素による温泉作用の研究(1)芒硝泉入浴による硫酸イオンの体内進入について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using Na(2)SO(4) labelled with S(35) transition of sulfate ion into the body across the skin was investigated soon after the bath in sodium sulfate solution at varying conditions. Mice were used as test animal. Percutaneous absorption of sulfate ion proved to be promoted at high bath temperature (45℃) than at indifferent temperature(37℃). stronger by the bath of longer duration (30min.) than by the bath of shorter duration (10min.), increased after repeated baths than after a single bath. It was accelerated by making a burn to the skin of the bathed animals. Layton and Dziewiatkowski proved that the parenterally administered sulfate ion was partly fixed in the connective tissue as chondroitin sulfate. The author had proved that chondroitin sulfate relieves pain, increases peripheral circulation and when administered parenterally promotes production of immune bodies. In Japan natural and artificial Glauber's salt spring bath are known to have a beneficial effect on wound healing, but no satisfactory explanation was given till today. Lith reported that a hypertonic solution of sodium sulfate promoten wound cure by external application and Seki showed that subcutaneous connective tissue of mice was stimulated by the bath in sodium sulfate spring. And so the abovementioned author's data seem to throw some light on solving the problem. en-copyright= kn-copyright= en-aut-name=OshimaYoshio en-aut-sei=Oshima en-aut-mei=Yoshio kn-aut-name=大島良雄 kn-aut-sei=大島 kn-aut-mei=良雄 aut-affil-num=1 ORCID= en-aut-name=YokotaTakeo en-aut-sei=Yokota en-aut-mei=Takeo kn-aut-name=横田剛男 kn-aut-sei=横田 kn-aut-mei=剛男 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所内科 affil-num=2 en-affil= kn-affil=岡山大学温泉研究所内科 END