| JaLCDOI | 10.18926/15096 |
|---|---|
| Title Alternative | 気管支喘息に対する複合温泉療法の作用機序 3.気道炎症反応との関連 |
| FullText URL | 067_099_106.pdf |
| Author | Hosaki, Yasuhiro| Mifune, Takashi| Mitsunobu, Fumihiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | The degree and characteristic of airway inflammation were evaluated by the proportions of bronchoalveolar lavage (BAL) cells. Clinical asthma types such as Ia. simple bronchoconstriction, Ib. bronchoconstriction + hypersecretion, and Ⅱ. bronchiolar obstruction correlate with airway inflammation. The increased proportion BAL neutrophils is characteristic of type Ⅱ asthma, and increase in BAL eosinophil count is often observed in type Ib asthma. Bronchial hyperresponsiveness also correlates with airway inflammation. Action of spa therapy has been speculated to be related to airway inflammation, since the therapy has no action inhibiting IgE-mediated allergic reaction. In fact, spa therapy is more effective in patients with type Ib and type Ⅱ than in those with type Ia showing slight degree of airway inflammation. Bronchial hyperresponsiveness is also improved by spa therapy. From a point of view, the direct action of spa therapy may be to clean airways and improve damaged mucous membrane of the airways, leading to suppression of airway inflammation. |
| Keywords | Spa therapy (温泉療法) Airway inflammation (気道炎症反応) BAL eosinophilia (BAL好酸球増多) BAL neutrophilia (BAL好中球増多) Bronchial asthma (気管支喘息) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 99 |
| End Page | 106 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307894 |
| JaLCDOI | 10.18926/15093 |
|---|---|
| Title Alternative | 気管支喘息に対する複合温泉療法の作用機序 1.温泉療法の評価方法との関連 |
| FullText URL | 067_085_091.pdf |
| Author | Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Action mechanisms of complex spa therapy (swimming training in a hot spring pool, inhalation with iodine salt solution, and fango therapy) were studied in relation to patient age, clinical asthma type, and airway inflammation. Actions of spa therapy were observed by two clinical effects : direct and indirect effects. Improvement of subjective symptoms, ventilatory function, and bronchial hyperresponsiveness was observed as direct effects of spa therapy, and improvement of suppressed function of adrenocortical glands as indirect effects of the therapy. The clinical effects of spa therapy were higher in patients over the age of 40. Regarding clinical asthma type, the effects were larger in patients with type Ib and type II asthma than in those with type Ia. The efficacy of spa therapy was closely related with airway inflammation in patients with type Ib and type II asthma. |
| Keywords | complex spa therapy (複合温泉療法) clinical asthma type (臨床病型) ventilatory function (換気機能) bronchial hyperresponsiveness (気道過敏性) adrenocortical glands (副腎皮質) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 85 |
| End Page | 91 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307192 |
| JaLCDOI | 10.18926/15094 |
|---|---|
| Title Alternative | 気管支喘息に対する複合温泉療法の作用機序 2.内分泌･自律神経系および心因的要素に対する効果 |
| FullText URL | 067_092_098.pdf |
| Author | Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Saito, Katsuyoshi| |
| Abstract | Actions of spa therapy on endocrine-autonomic nerve system and psychological factors were analyzed in patients with bronchial asthma. In endocrine function, serum levels of cortisol and ACTH tended to increase after spa therapy. In autonomic nerve system, decrease in concentrations of serum adrenalin and noradrenalin was observed after spa therapy, and the difference between the initial levels before spa therapy and the levels after the therapy was significant in serum levels of adrenalin. However, serum levels of substance P and Bradykinin were not affected by spa therapy. To evaluate the action of spa therapy on mental condition in patients with asthma, four kinds of psychological tests, CMI, SDS, CAl and SD, were carried out. Improvement of mental disorders in patients with asthma is observed after spa therapy in all psychological tests. These results suggest that spa therapy acts effectively on endocrine-autonomic nerve system and improve psychological conditions. |
| Keywords | Bronchial asthma (気管支喘息) Spa therapy (温泉療法) Endocrine-autonomic nerve system (内分泌・自律神経系) Psychological disorders (心的要素) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 92 |
| End Page | 98 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307879 |
| JaLCDOI | 10.18926/15008 |
|---|---|
| Title Alternative | 中高年発症型喘息患者におけるIgE系アレルギー反応の加令による変化 |
| FullText URL | 067_050_056.pdf |
| Author | Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Yokota, Satoshi| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Age-related changes in IgE-mediated allergic reaction were examined in patients with late onset asthma, whose asthma occured over the age at onset of 40. 1. The number of patients with a high serum IgE level over 3001U/mℓ was larger in those between the ages at onset of 40 and 49 and over age at onset 60 than in those between the ages at onset 50 and 59. 2. A positive RAST score to Hdm and cockroach allergens was more frequently found in patients between 40 and 49 and over age 60 at onset compared to those between 50 and 59 at onset. In contrast, the number of patients with a positive RAST to Candida was larger in those between 50 and 59 at onset than in those of between 40 and 49 and over 60 at onset. 3. Severe asthma was more frequently and slight asthma was less frequently observed in patients between 50 and 59 at onset than in those of the other age at onset groups. These results suggest that IgE-mediated allergic reaction in patients between the ages at onset of 50 and 59 is different from that in those with early onset asthma, and that the reaction in patients between the ages at onset 40 and 49 and over 60 resembles to the reaction in those with early onset asthma. |
| Keywords | IgE RAST 吸入抗原 (inhalant Allergen) 気管支喘息 (Bronchial asthma) 加令 (aging) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 50 |
| End Page | 56 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307989 |
| JaLCDOI | 10.18926/15002 |
|---|---|
| Title Alternative | Ia型(単純気管支れん縮型)喘息における気道過敏性について…年齢および気管支肺胞洗浄液中の細胞成分との関連について |
| FullText URL | 067_028_034.pdf |
| Author | Ashida, Kozo| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Bronchial hyperresponsiveness was examined in relation to age, ventilatory function, and the proportion of bronchoalveolar lavage (BAL) cells in 39 patients with type Ia asthma (simple bronchoconstriction) (25 with type Ia-1 and 14 with type Ia-2), classified by clinical symptoms. 1. The proportion of BAL eosinophils was significantly higher in type Ia-2 than that in type Ia-1 asthma patients. 2. Bronchial reactivity to methacholine was not different between type Ia-1 and type Ia-2 asthma patients. 3. Bronchial hyperreactivity tended to decrease as patient age was higher in both types of asthma. Neither ventilatory function (FEV1.0%) nor the proportions of BAL lymphocytes and neutrophils was not correlated with bronchial hyperresponsiveness in both types of asthma. 4. Bronchial reactivity to methacholine more dereased with the increase in the proportion of BAL eosinophils in both type Ia-1 and Ia-2 asthma patients. The results show that bronchial hyperresponsiveness in patients with type Ia asthma is correlated to patients age and the proportion of BAL eosinophils. |
| Keywords | Bronchial hyperresponsiveness Type Ia asthma Patient age BAL eosinophiIs |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 28 |
| End Page | 34 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307134 |
| JaLCDOI | 10.18926/14999 |
|---|---|
| Title Alternative | 肺活量(FVC)低値を示す気管支喘息の臨床的特徴 |
| FullText URL | 067_008_013.pdf |
| Author | Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Clinical features of asthma patients with a low % FVC (<75%) were studied in relation to clinical asthma type and disease severity. 1. The value of % FVC was not related to patient age. 2. A significant association between % FVC value and clinical asthma type was found. The value of % FVC was significantly lower in subjects with type Ⅱ asthma (bronchiolar obstruction) than in those with type Ia-1 and type Ia-2 (simple bronchoconstriction) (p<0.001). 3. % FVC value significantly correlated with disease severity. The value in the subjects tended to decrease as their asthma conditions were more severe. 4. The % FVC value in the subjects was improved after treatment (complex spa therapy). These results demonstrate that a significant correlation is present between low % FVC and disease severity in asthma patients with a low % FVC. |
| Keywords | % FVC低値 (Low % FVC) 気管支喘息 (Bronchial asthma) 臨床病型 (Clinical asthma type) 重症度 (asthma severity) 温泉療法 (Spa therapy) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 8 |
| End Page | 13 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308511 |
| JaLCDOI | 10.18926/14998 |
|---|---|
| Title Alternative | BAL液中好中球増加をともなわないⅡ型喘息について |
| FullText URL | 067_001_007.pdf |
| Author | Tanizaki, Yoshiro| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Tsuji, Takao| |
| Abstract | Clinical features of asthma patients with bronchiolar obstruction (type Ⅱ asthma) were studied in relation to the proportion of neutrophils in bronchoalveolar lavage (BAL) fluid. Of 13 subjects studied, 7 were accompanied with BAL neutrophilia (53.5%) (BALn(+)) and 6 were without BAL neutrophilia (3.5%) (BALn(-)). 1. The mean age was higher in BALn(-) (66.0 years) than in BALn(+) patients (55.0 years). 2. Bronchial reactivity to methacholine was slightly higher in BALn(-) patients than in those with BALn(+). 3. The value of FEV1.0% was significantly lower in BALn(+) patints than in those with BALn(-) (p<0.01). 4. The proportion of BAL lymphocytes was signicantly more decreased in BALn(+) patients compared to the proportion in those with BALn(-) (p<0.001). 5. the values of serum IgG, IgA, and IgM were not significantly different between BALn(+) and BALn(-) patients, however, the value of IgG was more decreased in BALn(+) patients than in those with BALn(-). These results suggest that two kinds of type Ⅱ asthma ; one is with BAL neutrophilia related to suppressed immunity, and another is without BAL neutrophilia in part due to aging. |
| Keywords | 気管支喘息 (Bronchial asthma) 細気管支閉塞 (Bronchiolar obstruction) BAL好中球 (BAL neutrophilia) 免疫能低下 (Suppressed immunity) 加齢 (Aging) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 1 |
| End Page | 7 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308171 |
| JaLCDOI | 10.18926/15006 |
|---|---|
| Title Alternative | 気管支喘息におけるエゴマ油と白血球のロイコトリエンB4,C4合成 |
| FullText URL | 067_035_042.pdf |
| Author | Ashida, Kozo| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Yokota, Satoshi| Tsugeno, Hirofumi| Tanizaki, Yoshiro| Yamamoto, Junko| Tsuji, Takao| |
| Abstract | In recent years, it has been noted that there is a close correlation between leukotrienes and late asthmatic reaction (LAR). In this study, effects of dietary supplementation with perilla seed oil rich in alpha-linolenic acid, which is speculated to affect the generation of leukotrienes through metabolism of arachidonic acid (AA), were evaluated in 6 patients with asthma. The symptoms and ventilatory function were improved after 2-week dietary supplementation with perilla seed oil. The generation of LTB4 and LTC4 by peripheral leucocytes stimulated with Ca ionophore A23187 was significantly suppressed by the dietary supplementation (LTB4 and LTC4 ; p<0.05). Regarding the composition of fatty acids in serum phospholipids, the concentrations of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and AA tended to increase after the supplementation, accompanied with an increase in the ratio of EPA to AA. These results suggest that dietary supplementation with perilla seed oil brings beneficial effects in the treatment of asthma. |
| Keywords | n-3系脂肪酸 (n-3 fatty acids) 気管支喘息 (bronchial asthma) アラキドン酸 (arachidonic acid) LTB4 LTC4 |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 35 |
| End Page | 42 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307804 |
| JaLCDOI | 10.18926/15000 |
|---|---|
| Title Alternative | Ⅱ型(細気管支閉塞)喘息と閉塞性細気管支炎における細気管支領域の炎症反応の差 |
| FullText URL | 067_014_020.pdf |
| Author | Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine| |
| Abstract | Ventilatory function and inflammatory cells in airways were compared between patients with type Ⅱ (bronchiolar obstruction) asthma and those with obstructive bronchiolitis. 1. Age and age at onset were higher in patients with type Ⅱ asthma than in those with obstructive bronchiolitis. IgE-mediated allergic reaction was observed in patients with type Ⅱ asthma, but not in those with obstructive bronchiolitis. 2. In ventilatory function tests, all ventilatory parameters examined were lower in patients with type Ⅱ asthma compared to those with obstructive bronchiolitis, and the differences were significant in FEV1.0% (p<0.001), % MMF (p<0.02), and V50 (p<0.01). 3. The proportion of BAL neutrophils was very high in type Ⅱ asthma (55.7%) and obstructive bronchiolitis (74.4%), however, this was not significant. 4. Absolute numbers/BAL fluid of total cells, BAL macrophages and BAL neutrophils were significantly higher in patients with obstructive bronchiolitis than in those with type Ⅱ asthma. 5. The results on absolute number/mℓ of BAL cells demonstrated that number of BAL neutrophils markedly larger in patients with obstructive bronchiolitis compared to those with type Ⅱ asthma. These results show that high proportion of BAL neutrophils was observed in the two respiratory diseases, however, the degree of inflammation in airways was markedly greater in obstructive bronchiolitis. |
| Keywords | Ⅱ型喘息 (Type Ⅱasthma) 閉塞性細気管支炎 (Obstructive bronchiolitis) 換気機能 (Ventilatory function) BAL好中球 (BAL neutrophiIs) IgE系反応 (IgE-mediated allergy) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 14 |
| End Page | 20 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307471 |
| JaLCDOI | 10.18926/15001 |
|---|---|
| Title Alternative | アトピー型および非アトピー型気管支喘息の発作発症機序の差異について･･･ロイコトリエンC4の役割について |
| FullText URL | 067_021_027.pdf |
| Author | Ashida, Kozo| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Yokota, Satoshi| Tsugeno, Hirofumi| Tanizaki, Yoshiro| |
| Abstract | Concentrations of main bronchoconstricting chemical mediators, histamine and leukotriene C4 (LTC4), were measured in bronchoalveolar lavage (BAL) fluid, and when cells (peripheral leukocytes and BAL cells) were stimulated by Ca ionophore A23187, in 7 atopic and 7 nonatopic asthma patients. 1. The proportion of basophilic cells was significantly larger in atopic than in nonatopic asthma (p<0.05), however no significant difference was present in the other BAL cells between the two asthma types. 2. Concentration of histamine in BAL fluid was significantly higher in atopic than that in nonatopic asthma, however, difference in that of LTC4 was not found between them. 4. The release of LTC 4 from BAL cells was higher in nonatopic than that in atopic asthma, but this was not significant. In contrast, the release of histamine was significantly higher in atopic compared to that in nonatopic asthma (p<0.001) when the cells were stimulated by Ca ionophore A23187. These results suggest that both histamine and LTC4 participate in the onset mechanism of atopic asthma, and only LTC4 in that of nonatopic asthma. |
| Keywords | Histamine LTC4 atopic nonatopic BAL cells |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 21 |
| End Page | 27 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307446 |
| JaLCDOI | 10.18926/15088 |
|---|---|
| Title Alternative | サーモグラフィーによる体表面温度の測定 |
| FullText URL | 067_063_070.pdf |
| Author | Hosaki, Yasuhiro| Nawa, Yuichiro| Takeuchi, Kazuaki| Tsugeno, Hirofumi| Ashida, Kozo| Yokota, Satoshi| Mitsunobu, Fumihiro| Mifune, Takashi| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| Ikeda, Satoru| Taketa, Kazuhisa| |
| Abstract | Body Surface Temperature was observed by thermography. The surface temperature of a healthy person's lower limbs, after being cooled in a water bath, increased in parallel with time. Patients with Diabetes Mellitus had different patterns in the rate of increase of the surface temperature. After cold loading, one patient had a 99% recovery ratio of surface temperature, the same level as healthy volunteers (83%, and 88%), as calculated by a picture processing program with the computerized thermotracer. However, the recovery ratio of other patients was poorer, ranging from 56% to under 6% recovery. This measurement of elevation of body temperature is useful for the estimation of peripheral blood flow in patients with lower limbcirculation failure. |
| Keywords | Thermography (サーモグラフィー) Diabetes Mellitus (糖尿病) Peripheral Circulation (末梢循環) Cold Loading (冷水負荷) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 63 |
| End Page | 70 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307566 |
| JaLCDOI | 10.18926/15007 |
|---|---|
| Title Alternative | 温泉療法による気管支喘息患者の心理的障害の改善 |
| FullText URL | 067_043_049.pdf |
| Author | Yokota, Satoshi| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Tada, Shinya| Harada, Mine| |
| Abstract | To evaluate improvement of mental disorders by spa therapy for 1-2 months, three kinds of psychological examinations, CMI (Cornel Medical Index), SDS (Selfrating Depression Scale) and CAI (Comprehensive Asthma Inventory) tests, were performed in 37 patients with asthma before and after spa therapy. 1. In CMI test, the scores of physical symptoms, respiratory symptoms, and CIJ symptoms significantly decreased after spa therapy. The score of psychical symptoms tended to decrease after the therapy, however, this was not significant. 2. The mean score of the subjects over 40 points in SDS test significantly decreased from 45.7 points before spa therapy to 37.5 after the therapy. 3. Mental disorders evaluated by various categories in CAI test were significantly improved after spa therapy. The average score in CAI test significantly decreased from 37.1 to 27.8 after the therapy. These results demonstrate that psychological disorders in patients with asthma are improved by spa therapy. |
| Keywords | 気管支喘息 (Bronchial asthma) 温泉療法 (Spa therapy) 心理テスト（CMI, SDS, CAI) (CMI test, SDS test, CAI test) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 43 |
| End Page | 49 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307273 |
| JaLCDOI | 10.18926/15087 |
|---|---|
| Title Alternative | 気管支喘息症例に対する鼻腔内ステロイド療法 |
| FullText URL | 067_057_062.pdf |
| Author | Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Bronchial asthma is often accompanied with allergic rhinitis or chronic sinusitis. Mucosal abnormalities of sinonasal cavity may influence lower respiratory responses in patients with asthma. We experienced a case of 72-year-old woman with asthma, who had dyspnea on exertion and a large volume of expectoration of more than 100mℓ a day. Furthermore she had nasal symptoms (nasal obstruction and rhinorrea) with prominent post-nasal discharge. Computed tomography (CT) scans of sinonasal cavity revealed marked thickness of nasal mucosa. Although her asthma symptoms such as wheezing and dyspnea improved by administration of bronchodialators, antiallergic agent, and beclomethason di isocyanate (BDI) accompanied with spa therapy after admission, the volume of expectoration revealed no decrease and her peak expiratory flow (PEF) didn't increase. The volume of expectoration and the PEF showed marked improvement after starting of intranasal glucocorticoid therapy. It is suggested from her clinical course that treatment with intranasal glucocorticoids is very important in asthmatic patients with mucosal abnormalities of sinonasal cavity. |
| Keywords | bronchial asthma (気管支喘息) rhinitis (鼻炎) intranasal steroid therapy (鼻腔内吸入ステロイド療法) expectoration (喀痰排出) peak expiratory flow (ピークフロー) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 57 |
| End Page | 62 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307814 |
| JaLCDOI | 10.18926/15091 |
|---|---|
| Title Alternative | Ⅱ型喘息(細気管支閉塞型)と気管支肺胞洗浄液の好中球数 |
| FullText URL | 067_079_084.pdf |
| Author | Tanizaki, Yoshiro| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Ochi, Koji| Harada, Hideo| Ikeda, Satoru| Taketa, Kazuhisa| |
| Abstract | Bronchial asthma is classified into three types ; type Ia (Ia-1 and Ia-2), type Ib, and type Ⅱ, by clinical symptoms (clinical diagnosis). Asthma is also classified by clinical findings and examinations (score diagnosis). Both classification systems show that markedly increased proportion of BAL neutrophils and marked decrease in % V25 value are characteristic of type Ⅱ, bronchiolar obstruction, asthma. However, there are some type Ⅱ asthma patients without BAL neutrophilia. In these patients, age is higher compared to those with BAL enutrophlia. Decrease in FEV1.0% value and decrease in the proportion of BAL lympocytes and serum IgG level, are not so remarkable as decrease in those with BAL neutrophilia. It has been suggested that type Ⅱ asthma with BAL neutrophilia correlates with suppression of humoral and cellular immunity, and same type of astma without BAL neutrophilia is in part caused by aging. |
| Keywords | Asthma classification (喘息分類) BAL lymphocytes (BALリンパ球) BAL neutrophils (BAL好中球) % V25 value Ⅱ型喘息 |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 79 |
| End Page | 84 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307924 |
| JaLCDOI | 10.18926/15111 |
|---|---|
| FullText URL | 067_134_146.pdf |
| Author | 寺崎 佳代| 山田 修子| 坂本 香須美| |
| Abstract | 私達はロイ看護モデルで事例を看護過程にそって展開することにした｡急性疾患では生命の危険があるものも少なくはなく,早期に治療とフォローが必要とされる｡それに加えて重要なことは患者自身病気に対し,恐怖にも近い不安を持つ｡患者は個人の中にある調節器対処機制と認知器対処機制によって環境の変化に対処していく｡対処した行動が適応行動か非効果的行動かは,四つの適応様式,つまり生理的,自己概念,役割機能,相互依存によって示される｡患者は自分に必要な行動を認知し,様々な環境に適応していかなければならない｡看護婦は効果的なコミュニケーションを用いて急性期の患者の行動をアセスメントし,適応行動か非効果的行動かを判定する｡その結果として四つの適応様式,それぞれに個人的特徴が強く現れる｡成人期の患者は個人の人生目標もあり,人生経験もある｡あるいは治療中に死に至ることもある｡そこで心理,社会的様式のアセスメントは特に個人の背景や価値観を理解した上でされなければならない｡患者の四つの適応様式,各々の適応を促進するために必要な介助を行うことは看護婦の役割であり,その人の健康や生活の質に貢献することができるものである｡ |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 134 |
| End Page | 146 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307386 |
| Author | Matsubara, Fumie| lnoue, Taeko| Mifune, Takashi| Tanizaki, Yoshiro| |
|---|---|
| Published Date | 1996-11 |
| Publication Title | 岡大三朝分院研究報告 |
| Volume | volume67 |
| Content Type | Data or Dataset |
| JaLCDOI | 10.18926/15090 |
|---|---|
| Title Alternative | Gastro-biliary motility in patients with non-ulcer dyspepsia |
| FullText URL | 067_075_078.pdf |
| Author | Mizushima, Takaaki| Yamamoto, Ryoichi| Matsumura, Naoki| Chowdhury, Riaz| Kato, Tadahiro| Ochi, Koji| Tanaka, Juntaro| Harada, Hideo| Yokota, Satoshi| Mitsunobu, Fumihiro| Mifune, Takashi| Tanizaki, Yoshiro| |
| Abstract | 現在,上腹部不定愁訴の原因は特定されていない｡その原因を解明するため,上腹部不定愁訴患者8人と健常対照者10人に対して液体食の胃排出能と,食事負荷による胆嚢収縮能を測定した｡胃排出時間,胆嚢収縮能はいずれも両者に有意な差は認められなかった｡健常対照者では胃排出時間と胆嚢収縮時間に有意な相関関係が認められたが,上腹部不定愁訴群では相関関係は認められなかった｡上腹部不定愁訴の原因として胃･胆嚢協調運動障害の存在が示唆 された。 |
| Keywords | 胃運動 (Gastric motility) 胆嚢運動 (Biliary motility) 不定愁訴 (indefinite complaint) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 75 |
| End Page | 78 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308012 |
| JaLCDOI | 10.18926/15110 |
|---|---|
| FullText URL | 067_126_133.pdf |
| Author | 中村 寿美江| 細田 つる子| 中村 あけみ| 寺崎 佳代| 吉尾 慶子| 伊賀 真由美| 土海 智穂| |
| Keywords | 外来看護 記録 データベース |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 126 |
| End Page | 133 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307403 |
| JaLCDOI | 10.18926/15089 |
|---|---|
| Title Alternative | Usefulness of retinol binding protein as a marker for the assessment of nutritional uptake for the preparation of colonosocpy |
| FullText URL | 067_071_074.pdf |
| Author | Kato, Tadahiro| Hasuoka, Hideaki| Ochi, Koji| Mizushima, Takaaki| Chowdhury Riaz| Matsumura, Naoki| Yamamoto, Ryoichi| Tanaka, Juntaro| Harada, Hideo| Akiyama, Tsuneo| Yokota, Satoshi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| |
| Abstract | 大腸内視鏡検査の前処置を栄養面から評価する目的で前処置前後にrapid turnover proteinである血中レチノール結合蛋白の変動を検討した｡前日に普通食を用い,当日ニフレックを使用した10例,検査1日前に低残渣食を用いた27例,通常の前処置では良好な腸管洗浄が得られないために検査前2日間低残渣食を用いた27例の3群について,前処置開始前と検査終了後に血中レチノール結合蛋白の変動をみたところ,検査前2日間低残渣食服用群で有意の低下を認めた｡前日普通食群では検査前後で変化を認めず,1日低残渣食服用群では低下傾向を認めたが,有意差は認めなかった｡これまで前処置の成否は腸管洗浄度の面で評価されてきたが,血中レチノール結合蛋白を目標として用いることにより栄養面から評価することができることが考えられた。 |
| Keywords | レチノール結合蛋白 (retinol binding protein) 大腸内視鏡 (colonoscopy) 前処置 (preparation) 栄養評価 (nutritional assessment) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 71 |
| End Page | 74 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307681 |
| Author | 岡山大学医学部附属病院三朝分院| |
|---|---|
| Published Date | 1996-11 |
| Publication Title | 岡大三朝分院研究報告 |
| Volume | volume67 |
| Content Type | Others |
