start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=裏表紙・英文目次
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-sei=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-mei=
kn-aut-name=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-sei=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=投稿規程
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-sei=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-mei=
kn-aut-name=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-sei=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=75
end-page=85
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Publications and lectures in 1986
kn-title=業績集
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-sei=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-mei=
kn-aut-name=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-sei=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=73
end-page=74
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=事務部だより
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-sei=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-mei=
kn-aut-name=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-sei=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=71
end-page=72
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=看護部だより
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-sei=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-mei=
kn-aut-name=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-sei=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=表紙・目次
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-sei=Institute for Environmental Medicine, Okayama University Medical Scool
en-aut-mei=
kn-aut-name=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-sei=岡山大学医学部附属環境病態研究施設，岡山大学医学部附属病院三朝分院
kn-aut-mei=
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=69
end-page=70
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=第14回喘息児童の夏期教室へ参加して
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=高田信江
kn-aut-sei=高田
kn-aut-mei=信江
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院看護部
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=66
end-page=68
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=気管支喘息のリハビリテーションとアンケート調査結果
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=山田武司
kn-aut-sei=山田
kn-aut-mei=武司
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=リハビリテーション部
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=41
end-page=65
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=On climatology in Misasa spa (nineth report)
kn-title=三朝温泉地の気候について（第9報）
en-subtitle=
kn-subtitle=
en-abstract=Climatological data of the last 12 months (1985.4.1- 1986.3.31) obtained by the climate-autorecording system at the Misasa Medical Branch in Misasa spa, Tottori-Ken, Japan, are presented.
kn-abstract=われわれは1956年以降，三朝温泉地の気候要素について観測を行なってきているが，今回は第9報として，ひきつづき1985年4月1日から1986年3月末日までの1カ年の気象観測の資料を報告することとした。なお1985年4月1日以降は自動記録装置が備えられたので，今回の資料はすべてこの自動記録装置によるものである。
en-copyright=
kn-copyright=

en-aut-name=MatsubaraFumie
en-aut-sei=Matsubara
en-aut-mei=Fumie
kn-aut-name=松原扶美恵
kn-aut-sei=松原
kn-aut-mei=扶美恵
aut-affil-num=1
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=周藤真康
kn-aut-sei=周藤
kn-aut-mei=真康
aut-affil-num=2
ORCID=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=3
ORCID=

en-aut-name=MorinagaHiroshi
en-aut-sei=Morinaga
en-aut-mei=Hiroshi
kn-aut-name=森永寛
kn-aut-sei=森永
kn-aut-mei=寛
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=35
end-page=39
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Spa therapy for bronchial asthma 2. Clinical and fundamental evaluation procedures
kn-title=喘息の温泉療法2．臨床的並びに基礎的評価方法
en-subtitle=
kn-subtitle=
en-abstract=Evaluation procedures for effectiveness of spa therapy on bronchial asthma were discussed according to the reports published. The evaluation procedures could be divided into
tow groups : procedures by clinical observations and procedures by findings relating to action mechanisms of spa therapy. Clinical evaluations have been performed by
subjective and objective symptoms, the degree of reduction of drugs used for treatment of bronchial asthma, and improvement of each parameter in ventilatory function test. The results obtained by these procedures are frequently reported as clinical observations. On the other hand, evaluations based on the findings relating to action mechanisms of spa therapy have been carried out as follows : 1) observations for immuno-allergic reactions which play an important role in pathogenic mechanisms of
bronchial asthma. 2) observations for autonomic nerve system, and 3) for endocrine glands, which have a close correlation with onset mechanisms of bronchial asthma. The results obtained by these findings before and after spa
therapy are much interesting, and should be investigated furthermore.
kn-abstract=気管支喘息に対する温泉療法の効果が，これまでどのような評価方法により判定されてきているのかについて，若干の文献的考察を加えた。効果に対する評価方法は，臨床的評価と作用機序と関連した評価方法とに分けて考えることができる。臨床的評価方法としては，自，他覚症状の改善，同時に使用された薬剤の減量の程度，あるいは，肺機能検査の各パラメーターの変動の比較などの方法により行なわれている。一方作用機序と関連した評価では，喘息の発症機序とある程度関連した温泉療法の作用を中心に検討が加えられている。例えば，喘息の発症機序として重要な位置を占める免疫アレルギー反応，自立神経系，内分泌系などと関連した指標を用いて，その変動を観察することによって，効果を明らかにしようとする試みがなされている。これらの検討は極めて意義深いが，なお今後IgE系反応や気道の過敏性との関連
などについての追求が必要であるように考えられる。
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=1
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=周藤真康
kn-aut-sei=周藤
kn-aut-mei=真康
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部三朝分院内科
en-keyword=温泉療法 (spa therapy)
kn-keyword=温泉療法 (spa therapy)
en-keyword=気管支喘息 (bronchial asthrna)
kn-keyword=気管支喘息 (bronchial asthrna)
en-keyword=免疫アレルギー反応 (immuno-allergic reaction)
kn-keyword=免疫アレルギー反応 (immuno-allergic reaction)
en-keyword=自律神経系 (autonomic nerve)
kn-keyword=自律神経系 (autonomic nerve)
en-keyword=内分泌系 (endocrine)
kn-keyword=内分泌系 (endocrine)
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=31
end-page=34
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Spa therapy for bronchial asthma 1. Climatotherapy, its clinical effects
kn-title=喘息の温泉療法1．気候療法，その臨床効果
en-subtitle=
kn-subtitle=
en-abstract=Spa therapy includes influence of environmental factors, especially climate around the place at which spa therapy is performed. In the present article, the effects of environmental climate around the hot springs on bronchial　asthma were discussed according to the reports published. Mountain climate, sea climate and underground climate are reported to be effective for the therapy of bronchial asthma. Although these climates have shown remarkable effectiveness on bronchial asthma, each of them has climatic characteristics in treatment for bronchial asthma．
Mountain climate has low content of oxygen and low vapor pressure, and patients with bronchial asthma require several weeks to adapt themselves for the climate. Sea climate is rich in cations and anions, and Ca(2+) and Mg(2+) included in sea water aerosol act beneficially on mucous membrane of airways in patiepts with bronchial asthma. Underground climate includes a lot of anions, which activate the activity of mucous membrane and ability of clearance of airways. Each climate also activate the function of adrenal glands．
kn-abstract=気管支喘息に対する温泉療法，特に温泉所在地（保養地）の環境，すなわち気候条件の喘息に対する影響について，文献的考察を加えた。気候療法としては，主として山岳気候，海洋性気候，洞窟気候などが，喘息の治療に応用されている。これらの気候は，いずれも喘息に対して有効的に作用することが示されているが，それぞれの特徴を持っている。例えば，山岳気候は酸素分圧が低いこと，水蒸気圧が低いことなどが特徴であり，そのため生体がそれに適合するためにはある程度の時間が必要となる。一方海洋性気候は，海塩粒子を含んでおり，海水エロゾル中のカルシウムやマグネシウムなどが良い影響を与えると考えられている。また洞窟気候は，水分含量が均一であり，電解質，特に陰イオンが多く，これが粘膜活性や浄化活性を亢進させると言われている。またいずれの気候療法も，副腎皮質機能の活性化をもたらすと考えられている。
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=1
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=周藤真康
kn-aut-sei=周藤
kn-aut-mei=真康
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部三朝分院内科
en-keyword=気候療法 (climatotherapy)
kn-keyword=気候療法 (climatotherapy)
en-keyword=気管支喘息 (bronchial asthrna)
kn-keyword=気管支喘息 (bronchial asthrna)
en-keyword=山岳気候 (mountain climate)
kn-keyword=山岳気候 (mountain climate)
en-keyword=海洋性気候 (sea climate)
kn-keyword=海洋性気候 (sea climate)
en-keyword=洞窟気候 (underground climate)
kn-keyword=洞窟気候 (underground climate)
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=22
end-page=30
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical effects of serial artificial CO(2) baths on degenerative disorders in consideration of the improved tissue perfusion.
kn-title=人工炭酸泉連浴による微小循環改善の退行性病変に対する効果
en-subtitle=
kn-subtitle=
en-abstract=Tissue perfusion plays an important role in prognosis of the deteriorating connective tissue disorders. Tissue perfusion was evaluated before and after CO(2) treatment on the patients with connective tissue disorders by means of medical mass spectrometer. CO(2) treatment was performed in 2 ways ; one was with CO(2)-cabine, 20 litres per minute at 40℃ for 20 minutes, and the other was with an artificial CO(2) bathing prepared with 2 tablets of BUB-KAO, a 50 g sodium hydrogencarbonate and succinic acid tablet, in 280-litre-tub at 40℃ for 20 minutes. Case 1, 33-year-old female, suffering from chronic rheumatic arthritis with rheumatic thromboangiitis obliterans in the left 5th toe. Main arterial trees were found intact arteriographically. Her joint pain and muscle stiffness
have been improved markedly after CO(2) treatment with cabin every day for one month though every medicine for rheumatism made little effect. Case 2, 46-year-old female, suffered from progressive systemic scleroderma. Major blood supply was found not blocked in upper extremities
arteriographically. Tissue perfusion was found poor in muscle tissue of each forearm before CO(2) treatment with cabin, whereas an improved tissue perfusion was confirmed after one month of serial CO(2) treatment, leading to ameliorate persistent muscle stiffness, though every medicine for her made slow effect. Case 3, 48-year-old female, suffering from the weakness in strength with no positive laboratory findings of connective tissue disorders. Tissue perfusion has been found quite improved
following serial artificial CO(2) bathings for 12 months, being able to work hard every day as a nurse. Serial CO(2) bathing is thought to be very useful in ameliorating the symptoms of deteriorating connective disorders by virtue of an improved tissue perfusion.
kn-abstract=組織循環の良不良は，結合織の退行性病変の予後に大いに影響をおよぼすものである。人工炭酸泉を用いた実験的検討で，すでに組織循環の30　％　増加を認めており，臨床的治験により好傾向を示す結果を得つつある。結合織病変を主とする慢性疾患4症例の治験前後に局所組織流量を測定して評価することができた。局所組織流量は医用質量分析装置を介したオンラインシステムで測定計算した。人工炭酸浴は，炭酸ガスキャビン，および人工炭酸浴剤浴を用いた。人工炭酸泉浴は，1カ月より1年におよび，それぞれ自覚症状の著名な改善と，組織流量の増加を定量しえた。人工炭酸泉の連浴による組織流量の改善は、結合織の退行性病変に有効に作用するものである。
en-copyright=
kn-copyright=

en-aut-name=KomotoYoshiaki
en-aut-sei=Komoto
en-aut-mei=Yoshiaki
kn-aut-name=古元嘉昭
kn-aut-sei=古元
kn-aut-mei=嘉昭
aut-affil-num=1
ORCID=

en-aut-name=KohmotoTomoji
en-aut-sei=Kohmoto
en-aut-mei=Tomoji
kn-aut-name=河本知二
kn-aut-sei=河本
kn-aut-mei=知二
aut-affil-num=2
ORCID=

en-aut-name=SunakawaMitsuru
en-aut-sei=Sunakawa
en-aut-mei=Mitsuru
kn-aut-name=砂川満
kn-aut-sei=砂川
kn-aut-mei=満
aut-affil-num=3
ORCID=

en-aut-name=YagiNobuko
en-aut-sei=Yagi
en-aut-mei=Nobuko
kn-aut-name=矢木信子
kn-aut-sei=矢木
kn-aut-mei=信子
aut-affil-num=4
ORCID=

en-aut-name=YorozuHidenori
en-aut-sei=Yorozu
en-aut-mei=Hidenori
kn-aut-name=萬秀憲
kn-aut-sei=萬
kn-aut-mei=秀憲
aut-affil-num=5
ORCID=

en-aut-name=MatsumotoYasunobu
en-aut-sei=Matsumoto
en-aut-mei=Yasunobu
kn-aut-name=松本泰伸
kn-aut-sei=松本
kn-aut-mei=泰伸
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設

affil-num=5
en-affil=
kn-affil=花王株式会社栃木研究所

affil-num=6
en-affil=
kn-affil=花王株式会社栃木研究所
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=17
end-page=21
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The simplified method of measuring Radon in mineral waters by the liquid scintillation counter.
kn-title=液体シンチレーション計数器を用いるRn-222の簡易定量法
en-subtitle=
kn-subtitle=
en-abstract=Radon in mineral waters was determined with simplicity by newly developed method. In this method, 2.0mℓ of water sample was directly mixed with 15 mℓ of Hionic-Fluor in a vial, which was then filled up with additional Hionic-Fluor ; 190 minutes were allowed for the radioactivity to equilibrate. The radioactiviity of Radon was measured by the Liquid Scintillation Counter (Tri-Carb 460C). Radon content was easily calculated with the proposed formula by an electric desk calculater. The reproducibility was proved CV=5.77 % ; the lowest detection limit was 0.2 nCi/l. An adequate correlation was obtained from the results of measurements compared with the original method ; r=0.996, y=0.818x×0.875.
kn-abstract=鉱泉水中のラドンを測定するため，抽出法を省略し，少量の試料水を直接液状シンチレーターに溶解し，液体シンチレーション計数器を用いて放射能を測定し，次いで簡単な計算法により試料水中のラドン濃度を計算する簡易定量法を試みた。本法を用いて一鉱泉水のラドンを反復測定した際の精度は，σ＝0.136nCi/l，CV＝5.77　％　，（x＝2.36n　Ci/l）であった。次に本法でのRnの最少検出量は，0.2nCi/lである。原法と本法とを用いて得られた測定値の間には，r＝0.996，y＝0.818x＋0.875なる相関関係が成立した。本法を使用すると，簡単な予備処理後，極短時間内にラドンの測定が可能なため，花崗岩地域の井水，鉱泉水中のラドンを定量するためには，有用な方法である。
en-copyright=
kn-copyright=

en-aut-name=MifuneMasaaki
en-aut-sei=Mifune
en-aut-mei=Masaaki
kn-aut-name=御舩政明
kn-aut-sei=御舩
kn-aut-mei=政明
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属病院三朝分院中央検査部
en-keyword=鉱泉水 (Mineral waters)
kn-keyword=鉱泉水 (Mineral waters)
en-keyword=ラドン (Radon)
kn-keyword=ラドン (Radon)
en-keyword=放射能泉 (Radioactive springs)
kn-keyword=放射能泉 (Radioactive springs)
en-keyword=液体シンチレーション計数器 (Liquid scintillation counter)
kn-keyword=液体シンチレーション計数器 (Liquid scintillation counter)
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=12
end-page=16
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effect of spa-drink therapy on exocrine pancreatic function
kn-title=膵外分泌機能におよぼす飲泉の効果
en-subtitle=
kn-subtitle=
en-abstract=The effect of spa-drink therapy (Misasa hot spring) on exocrine pancreatic function was studied on 18 patients after their physical and psychological conditions were stabilized about two weeks following hospitalization. Patients were randomly divided into two groups : eight patients into a control group (continuance of spa-bathing) and 10 patients into a spa-drink therapy group (continuance of spa-bathing plus commencement of spa-drink therapy). Spa-drink therapy refers to drinking 200mℓ of warm spa-water (42℃) two times a day : between meals in the morning and in the afternoon. Exocrine pancreatic
function was evaluated by fecal chymotrypsin activity, using a colorimetric method (Boehringer-Mannheim). Following results were obtained : 1) With 2-week's spa-drink therapy, fecal chymotrypsin activity was significantly enhanced in 40 % of the patients, while none of the controls showed an increase in fecal chymotrypsin
activity. 2) Fecal chymotrypsin activity at the time of 4 weeks was similar to that obtained at the time of 2 weeks in both groups. In conclusion, spa-drink therapy for 2
weeks was effective for the enhancement of exocrine pancreatic function.
kn-abstract=膵外分泌機能におよぼす飲泉（三朝温泉水）の効果を飲泉群および非飲泉群を対象として検討した。膵外分泌機能検査法としては，糞便中キモトリプシン活性比色測定法（モノテストカイモトリプシン）を用いた。その結果，糞便中キモトリプシン活性は，飲泉開始2週後に40　％　の患者で上昇し，4週後は2週後と変わらなかった。以上より，2週間の飲泉は膵外分泌機能を改善させる効果があることがわかった。
en-copyright=
kn-copyright=

en-aut-name=MatsumotoShuji
en-aut-sei=Matsumoto
en-aut-mei=Shuji
kn-aut-name=松本秀次
kn-aut-sei=松本
kn-aut-mei=秀次
aut-affil-num=1
ORCID=

en-aut-name=HaradaHideo
en-aut-sei=Harada
en-aut-mei=Hideo
kn-aut-name=原田英雄
kn-aut-sei=原田
kn-aut-mei=英雄
aut-affil-num=2
ORCID=

en-aut-name=OchiKoji
en-aut-sei=Ochi
en-aut-mei=Koji
kn-aut-name=越智浩二
kn-aut-sei=越智
kn-aut-mei=浩二
aut-affil-num=3
ORCID=

en-aut-name=TakedaMasahiko
en-aut-sei=Takeda
en-aut-mei=Masahiko
kn-aut-name=武田正彦
kn-aut-sei=武田
kn-aut-mei=正彦
aut-affil-num=4
ORCID=

en-aut-name=TanakaJuntaro
en-aut-sei=Tanaka
en-aut-mei=Juntaro
kn-aut-name=田中淳太郎
kn-aut-sei=田中
kn-aut-mei=淳太郎
aut-affil-num=5
ORCID=

en-aut-name=SenouToshinobu
en-aut-sei=Senou
en-aut-mei=Toshinobu
kn-aut-name=妹尾敏伸
kn-aut-sei=妹尾
kn-aut-mei=敏伸
aut-affil-num=6
ORCID=

en-aut-name=IrieSeiji
en-aut-sei=Irie
en-aut-mei=Seiji
kn-aut-name=入江誠治
kn-aut-sei=入江
kn-aut-mei=誠治
aut-affil-num=7
ORCID=

en-aut-name=IshibashiTadaaki
en-aut-sei=Ishibashi
en-aut-mei=Tadaaki
kn-aut-name=石橋忠明
kn-aut-sei=石橋
kn-aut-mei=忠明
aut-affil-num=8
ORCID=

en-aut-name=KimuraIkuro
en-aut-sei=Kimura
en-aut-mei=Ikuro
kn-aut-name=木村郁郎
kn-aut-sei=木村
kn-aut-mei=郁郎
aut-affil-num=9
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学分野

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学分野

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学分野

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学分野

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学分野

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学分野

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学分野

affil-num=8
en-affil=
kn-affil=岡山大学医学部第二内科

affil-num=9
en-affil=
kn-affil=岡山大学医学部第二内科
en-keyword=糞便中キモトリプシン活性 (Fecal chymotrypsin activity)
kn-keyword=糞便中キモトリプシン活性 (Fecal chymotrypsin activity)
en-keyword=飲泉療法 (Spa-drink therapy)
kn-keyword=飲泉療法 (Spa-drink therapy)
en-keyword=膵外分泌機能 (Pancreatic exocrine function)
kn-keyword=膵外分泌機能 (Pancreatic exocrine function)
en-keyword=膵 (Pancreas)
kn-keyword=膵 (Pancreas)
en-keyword=酵素 (Enzyme)
kn-keyword=酵素 (Enzyme)
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=5
end-page=11
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study on anti-allergic action of Terfenadine
kn-title=Terfenadineの抗アレルギー作用について
en-subtitle=
kn-subtitle=
en-abstract=Anti-allergic action of terfenadine, one of the H(1) receptor inhibitors, was examined by human basophil histamine release induced by anti-IgE or a specific allergen (house dust), and the release of leukotriens from leucocytes stimulated by Ca ionophore A23187. 1. Terfenadine did not inhibit the release of histamine from basophils of healthy subjects induced by anti-IgE, and also of patients with bronchial asthma induced by house dust when the in vitro examination was performed by a whole blood method. 2. Histamine release from basophils of patients with bronchial asthma was significantly inhibited
when washed leucocytes was preincubated with terfenadine in vitro. The release of LT B(4) from leucocytes was also inhibited. 3. In vivo examination of inhibitory action of terfenadine showed no effect on basophil histamine release of healthy subjects by anti-IgE and of asthmatic subjects by house dust, although skin test by house dust in these subjects was inhibited 60 min after administration in vivo.
These results show that terfenadine inhibits the release of chemical mediators from tissue mast cells, and basophils migrating into local allergic sites.
kn-abstract=選択的H(1)受容体拮抗薬であるTerfenadineの抗アレルギー作用，特にIgE系反応によるヒスタミン，およびCa ionophore A23187による好中球からのleukotrienes遊離に対する抑制作用を，ヒト末梢血白血球を用いて検討した。１．Terfenadineは，抗ヒトIgE刺激による健康人好塩基球および特異抗原刺激による気管支喘息患者好塩基球からのヒスタミン遊離に対して，全血法でのin vitro添加実験では有意の抑制作用を示さなかった。
2．洗浄白血球法によるin vitro添加実験では，Terfenadineは特異抗原および抗ヒトIgE刺激時の気管支喘息患者好塩基球からのヒスタミン，Ca ionophore　A23187刺激時のleukotriene B(4)遊離に対して有意の抑制効果を示した。3．Terfenadineの内服によるin vivoの抑制実験では，IgE系反応による健康人および気管支喘息患者好塩基球からのヒスタミン遊離に対して有意の抑制効果は見られなかったが，特異抗原による皮膚反応に対しては明らかな抑制作用が観察された。以上より，Terfenadineは，組織肥満細胞および組織へと遊走してきた好塩基球に対してはある程度の抑制作用を有しているものと考えられた。
en-copyright=
kn-copyright=

en-aut-name=TanizakiYoshiro
en-aut-sei=Tanizaki
en-aut-mei=Yoshiro
kn-aut-name=谷崎勝朗
kn-aut-sei=谷崎
kn-aut-mei=勝朗
aut-affil-num=1
ORCID=

en-aut-name=KomagoeHaruki
en-aut-sei=Komagoe
en-aut-mei=Haruki
kn-aut-name=駒越春樹
kn-aut-sei=駒越
kn-aut-mei=春樹
aut-affil-num=2
ORCID=

en-aut-name=SudoMichiyasu
en-aut-sei=Sudo
en-aut-mei=Michiyasu
kn-aut-name=周藤真康
kn-aut-sei=周藤
kn-aut-mei=真康
aut-affil-num=3
ORCID=

en-aut-name=KitaniHikaru
en-aut-sei=Kitani
en-aut-mei=Hikaru
kn-aut-name=貴谷光
kn-aut-sei=貴谷
kn-aut-mei=光
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部三朝分院内科

affil-num=2
en-affil=
kn-affil=岡山大学医学部三朝分院内科

affil-num=3
en-affil=
kn-affil=岡山大学医学部三朝分院内科

affil-num=4
en-affil=
kn-affil=岡山大学医学部三朝分院内科
en-keyword=夕一フェナンジン (Terfenadine)
kn-keyword=夕一フェナンジン (Terfenadine)
en-keyword=lgE系反応 (IgE-mediated reaction)
kn-keyword=lgE系反応 (IgE-mediated reaction)
en-keyword=ヒスタミン (histamine)
kn-keyword=ヒスタミン (histamine)
en-keyword=好塩基球 (basophils)
kn-keyword=好塩基球 (basophils)
END

start-ver=1.4
cd-journal=joma
no-vol=58
cd-vols=
no-issue=
article-no=
start-page=1
end-page=4
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=198708
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Short term effect of spa-water on gastric mucosal blood flow
kn-title=胃粘膜血流に及ぼす温泉水の効果
en-subtitle=
kn-subtitle=
en-abstract=Short-term effects of spa-drink therapy on gastric mucosal blood flow were evaluated by an endoscopic organ reflex spectrophotometry, using Olympus XQ-10. Thirty-four subjects were randomly divided into three groups : 10 subjects for warm spa-water (40±C) infusion group, 10 subjects for warm tap-water infusion group, and 14 subjects for warm air infusion group. Intragastric infusion of water or air was performed through the fiberscopic infusion channel. Gastric mucosal blood flow was determined just before and 10 min after the infusion on the three points of gastric mucosa : lesser curvature of the angle, the antrum and the pylorus. Following results were obtained : 1) Spa-water exerted a beneficial effect on gastric mucosal blood flow as compared to air. The difference was statistically significant on all of the three points. 2) Spa-water tended to exert a beneficial effect on gastric mucosal blood flow as compared to tap-water. The difference, however, was significant only on the mucosa of the gastric antrum. In conclusion, it was suggested that spa-drink therapy was useful for the treatment of chronic gastritis and gastric ulcer in which impairment of gastric mucosal blood flow plays an important pathogenetic role. Studies on the long-term effects of spa-drink therapy on the gastric mucosal blood flow are now in progress.
kn-abstract=臓器反射スペクトル法と内視鏡を併用して胃粘膜血流を測定し，当院温泉水飲用の消化機能に対する基礎的検討を胃粘膜血流を指標に行なった。温泉水の対照として空気と白湯を選び3群に分け検討した。その結果，温泉水は空気に比し胃粘膜血流を増加させる作用を有していることが示唆された。また温泉水は部分的ではあるが白湯にくらべても胃粘膜血流を増加させる作用があることが示唆された。よって飲泉療法の消化器疾患に対する臨床的有用性が胃粘膜血流の面からもうかがわれた。
en-copyright=
kn-copyright=

en-aut-name=TanakaJuntarou
en-aut-sei=Tanaka
en-aut-mei=Juntarou
kn-aut-name=田中淳太郎
kn-aut-sei=田中
kn-aut-mei=淳太郎
aut-affil-num=1
ORCID=

en-aut-name=MatumotoShuuji
en-aut-sei=Matumoto
en-aut-mei=Shuuji
kn-aut-name=松本秀次
kn-aut-sei=松本
kn-aut-mei=秀次
aut-affil-num=2
ORCID=

en-aut-name=SenouToshinobu
en-aut-sei=Senou
en-aut-mei=Toshinobu
kn-aut-name=妹尾敏伸
kn-aut-sei=妹尾
kn-aut-mei=敏伸
aut-affil-num=3
ORCID=

en-aut-name=IrieSeiji
en-aut-sei=Irie
en-aut-mei=Seiji
kn-aut-name=入江誠治
kn-aut-sei=入江
kn-aut-mei=誠治
aut-affil-num=4
ORCID=

en-aut-name=OchiKouji
en-aut-sei=Ochi
en-aut-mei=Kouji
kn-aut-name=越智浩二
kn-aut-sei=越智
kn-aut-mei=浩二
aut-affil-num=5
ORCID=

en-aut-name=TakedaMasahiko
en-aut-sei=Takeda
en-aut-mei=Masahiko
kn-aut-name=武田正彦
kn-aut-sei=武田
kn-aut-mei=正彦
aut-affil-num=6
ORCID=

en-aut-name=HaradaHideo
en-aut-sei=Harada
en-aut-mei=Hideo
kn-aut-name=原田英雄
kn-aut-sei=原田
kn-aut-mei=英雄
aut-affil-num=7
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学部門

affil-num=2
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学部門

affil-num=3
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学部門

affil-num=4
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学部門

affil-num=5
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学部門

affil-num=6
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学部門

affil-num=7
en-affil=
kn-affil=岡山大学医学部附属環境病態研究施設成人病学部門
en-keyword=飲泉療法 (Spa-drink therapy)
kn-keyword=飲泉療法 (Spa-drink therapy)
en-keyword=消化器機能 (Digestive function)
kn-keyword=消化器機能 (Digestive function)
en-keyword=胃粘膜血流 (Gastric mucosal blood flow)
kn-keyword=胃粘膜血流 (Gastric mucosal blood flow)
en-keyword=臓器反射スペクトル法 (Organ reflex spectrophotometry)
kn-keyword=臓器反射スペクトル法 (Organ reflex spectrophotometry)
END