start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=23 end-page=28 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=好塩基球からのヒスタミン遊離に関する研究. 1 自動分析装置による全血からのヒスタミン遊離の測定 kn-title=Studies on the release of histamine from basophils 1. Determination of histamine from whole blood by an automated fluorometric histamine analysis system en-subtitle= kn-subtitle= en-abstract=ヒスタミン自動分析装置により,健康人10名,気管支喘息23例の全血からのヒスタミン遊離を測定した. 抗ヒトIgEを添加した際のヒスタミン遊離は,健康人および外因性気管支喘息症例では有意の増加傾向を示したが,一方内因性喘息症例では遊離増加はほとんどみられなかった. ハウスダスト抗原添加では,ハウスダストが抗原である気管支喘息症例においてのみ全血からの有意のヒスタミン遊離の増加が観察された. 以上の結果より,ヒスタミン自動分析装置による全血からの遊離ヒスタミンの測定は,気管支喘息の病態解明の1手段として極めて有用であると考えられる. kn-abstract=Histamine released from whole blood was determined by an automated fiuorometric histamine analysis system. The increased release of histamine from basophils by anti-IgE was observed in ten healthy subjects and 12 extrinsic asthma patients, while the release in 11 intrinsic asthma patients was significantly less as compared to that in healthy and extrinsic asthma subjects. House dust extract caused a significant increase in the histamine release from basophils of the extrinsic asthma patients who are sensitive to house dust. It was concluded from this study that histamine released from basophils could be easily determined by an automated analysis system and that the method is useful for the diagnosis and study of allergy. en-copyright= kn-copyright= en-aut-name=TanizakiYoshiro en-aut-sei=Tanizaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=1 ORCID= en-aut-name=KomagoeHaruki en-aut-sei=Komagoe en-aut-mei=Haruki kn-aut-name=駒越春樹 kn-aut-sei=駒越 kn-aut-mei=春樹 aut-affil-num=2 ORCID= en-aut-name=SudoMichiyasu en-aut-sei=Sudo en-aut-mei=Michiyasu kn-aut-name=周藤真康 kn-aut-sei=周藤 kn-aut-mei=真康 aut-affil-num=3 ORCID= en-aut-name=MifuneMasaaki en-aut-sei=Mifune en-aut-mei=Masaaki kn-aut-name=御般政明 kn-aut-sei=御般 kn-aut-mei=政明 aut-affil-num=4 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=5 ORCID= en-aut-name=OhtaniJun en-aut-sei=Ohtani en-aut-mei=Jun kn-aut-name=大谷純 kn-aut-sei=大谷 kn-aut-mei=純 aut-affil-num=6 ORCID= en-aut-name=KitaniHikaru en-aut-sei=Kitani en-aut-mei=Hikaru kn-aut-name=貴谷光 kn-aut-sei=貴谷 kn-aut-mei=光 aut-affil-num=7 ORCID= en-aut-name=GodaYoshinori en-aut-sei=Goda en-aut-mei=Yoshinori kn-aut-name=合田吉徳 kn-aut-sei=合田 kn-aut-mei=吉徳 aut-affil-num=8 ORCID= en-aut-name=TadaShinya en-aut-sei=Tada en-aut-mei=Shinya kn-aut-name=多田慎也 kn-aut-sei=多田 kn-aut-mei=慎也 aut-affil-num=9 ORCID= en-aut-name=KimuraIkuro en-aut-sei=Kimura en-aut-mei=Ikuro kn-aut-name=木村郁郎 kn-aut-sei=木村 kn-aut-mei=郁郎 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院第2内科 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院第2内科 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院第2内科 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院第2内科 affil-num=10 en-affil= kn-affil=岡山大学医学部附属病院第2内科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=29 end-page=33 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=好塩基球からのヒスタミン遊離に関する研究. 2. ハウスダスト抗原および抗ヒトIgEによるヒスタミン遊離 kn-title=Studies on the release of histamine from basophils 2. Histamine release induced by house dust extract and anti-IgE en-subtitle= kn-subtitle= en-abstract=好塩基球からのIgE-mediated histamine releaseの機序を,健康人(2名)および気管支喘息(4例)それぞれの代表例で比較検討した. 抗ヒトIgEの添加濃度別検討では,健康人および外因性喘息例いずれも有意のヒスタミン遊離の増加をしめしたが,Max. % histamine releaseをひきおこす抗ヒトIgEの濃度は比較的限られた範囲内にある傾向がみられた. 一方内因性喘息例では,いずれの抗ヒトIgE濃度でも有意のヒスタミン遊離はみられなかった. ハウスダスト抗原の添加濃度別検討では,ハウスダストが抗原である気管支喘息症例においてdose-dependentなヒスタミン遊離が観察されたが,使用された抗原濃度の範囲ではMax. % releaseをひきおこす至適濃度は明らかでなかった. kn-abstract=IgE-mediated release of histamine from whole blood was examined in two healthy and four asthmatic subjects by dose-dependent fashion. The significantly increased amount of histamine was released from basophils of both healthy and asthmatic subjects by a limited concentration of anti-IgE. Antigen (house dust) caused histamine release only from basophils of asthmatics who are sensitive to house dust. Basophils from one patients with asthma released no significant amount of histamine by anti-IgE. en-copyright= kn-copyright= en-aut-name=TanizakiYoshiro en-aut-sei=Tanizaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=1 ORCID= en-aut-name=KomagoeHaruki en-aut-sei=Komagoe en-aut-mei=Haruki kn-aut-name=駒越春樹 kn-aut-sei=駒越 kn-aut-mei=春樹 aut-affil-num=2 ORCID= en-aut-name=SudoMichiyasu en-aut-sei=Sudo en-aut-mei=Michiyasu kn-aut-name=周藤真康 kn-aut-sei=周藤 kn-aut-mei=真康 aut-affil-num=3 ORCID= en-aut-name=MifuneMasaaki en-aut-sei=Mifune en-aut-mei=Masaaki kn-aut-name=御般政明 kn-aut-sei=御般 kn-aut-mei=政明 aut-affil-num=4 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=5 ORCID= en-aut-name=KitaniHikaru en-aut-sei=Kitani en-aut-mei=Hikaru kn-aut-name=貴谷光 kn-aut-sei=貴谷 kn-aut-mei=光 aut-affil-num=6 ORCID= en-aut-name=GodaYoshinori en-aut-sei=Goda en-aut-mei=Yoshinori kn-aut-name=合田吉徳 kn-aut-sei=合田 kn-aut-mei=吉徳 aut-affil-num=7 ORCID= en-aut-name=TadaShinya en-aut-sei=Tada en-aut-mei=Shinya kn-aut-name=多田慎也 kn-aut-sei=多田 kn-aut-mei=慎也 aut-affil-num=8 ORCID= en-aut-name=KimuraIkuro en-aut-sei=Kimura en-aut-mei=Ikuro kn-aut-name=木村郁郎 kn-aut-sei=木村 kn-aut-mei=郁郎 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院第2内科 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院第2内科 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院第2内科 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院第2内科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=77 end-page=84 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Comparison of sulfur isotope ratio measurements by various techniques, and the δ(34)S values of some sulur standards kn-title=イオウ同位体比分析法の比較検討と同位体比標準物質の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Three techniques (combustion of Ag(2)S by Cu(2)O, thermal decomposition of BaSO(4) and KIBA reagent method under vacuum) for sulfur isotope ratio measurements of geological samples are described in detail. The δ(34)S values of three working standards (MSS-2, MSS-3 and MSS-4) obtained by these techniques for the last 13 years were compared (Table 1 and Fig. 3): the most acceptable values of the three standards are +21.5, +3.5 and +4.5‰, respectively. en-copyright= kn-copyright= en-aut-name=YanagisawaFumitaka en-aut-sei=Yanagisawa en-aut-mei=Fumitaka kn-aut-name=柳沢文孝 kn-aut-sei=柳沢 kn-aut-mei=文孝 aut-affil-num=1 ORCID= en-aut-name=MiyoshiTadashi en-aut-sei=Miyoshi en-aut-mei=Tadashi kn-aut-name=三好正 kn-aut-sei=三好 kn-aut-mei=正 aut-affil-num=2 ORCID= en-aut-name=UedaAkira en-aut-sei=Ueda en-aut-mei=Akira kn-aut-name=上田晃 kn-aut-sei=上田 kn-aut-mei=晃 aut-affil-num=3 ORCID= en-aut-name=SakaiHitoshi en-aut-sei=Sakai en-aut-mei=Hitoshi kn-aut-name=酒井均 kn-aut-sei=酒井 kn-aut-mei=均 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所熱水地球化学部門 affil-num=2 en-affil= kn-affil=岡山大学温泉研究所熱水地球化学部門 affil-num=3 en-affil= kn-affil=岡山大学温泉研究所熱水地球化学部門 affil-num=4 en-affil= kn-affil=岡山大学温泉研究所熱水地球化学部門 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=85 end-page=86 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Impressions on European institutes of balneology kn-title=ヨーロッパ温泉地の訪問印象記 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HaradaHideo en-aut-sei=Harada en-aut-mei=Hideo kn-aut-name=原田英雄 kn-aut-sei=原田 kn-aut-mei=英雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所温泉内科学 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=61 end-page=65 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case report of a patient with chronic pancreatitis successfully treated by endoscopic elimination of protein plugs kn-title=内視鏡的protein plug除去術により寛解を得た慢性膵炎の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Presented here is a case report of a 56 years old male patient with chronic pancreatitis in which a dramatic improvement in symptoms and objective findings were noted after endoscopic elimination of protein plugs. In September, 1979, he had an acute onset of pancreatitis followed by pseudocyst formation and the following combined operations were performed: resection of the pseudocyst, resection of the body and tail of the pancreas along with the spleen, partial resection of the stomach and the transverse colon, and gastroenterostomy according to Billroth I method. He had been followed up at out-patient clinic for chronic pancreatitis and diabetes until January 14,1979 when he was hospitalized for anorexia, loss of weight, pretibial edema, and upper-abdominal pain. The patient's condition was characterized by emaciation (height 152 cm, weight 37 kg), anemia (Hb 7.9g/dl), hypoproteinemia (serum protein 4.2 g/dl) , and hypolipidemia (total cholesterol 73 mg/dl). Abdominal ultrasound, abdominal CT and ERCP revealed stones in the pancreatic duct. Symptoms and objective findings were only partially improved by medical regimens. Subsequently we performed endoscopic cannulation of the pancreatic duct for elimination of pancreatic stones. Successful elimination of large numbers of protein plugs resulted in dramatic improvement of symptoms and objective findings. This procedure proved to add a new important tool in the treatment of chronic pancreatitis. en-copyright= kn-copyright= en-aut-name=TakedaMasahiko en-aut-sei=Takeda en-aut-mei=Masahiko kn-aut-name=武田正彦 kn-aut-sei=武田 kn-aut-mei=正彦 aut-affil-num=1 ORCID= en-aut-name=TanakaJuntaro en-aut-sei=Tanaka en-aut-mei=Juntaro kn-aut-name=田中淳太郎 kn-aut-sei=田中 kn-aut-mei=淳太郎 aut-affil-num=2 ORCID= en-aut-name=TakasugiKiyoshi en-aut-sei=Takasugi en-aut-mei=Kiyoshi kn-aut-name=高杉潔 kn-aut-sei=高杉 kn-aut-mei=潔 aut-affil-num=3 ORCID= en-aut-name=HaradaHideo en-aut-sei=Harada en-aut-mei=Hideo kn-aut-name=原田英雄 kn-aut-sei=原田 kn-aut-mei=英雄 aut-affil-num=4 ORCID= en-aut-name=ManjiTadatomi en-aut-sei=Manji en-aut-mei=Tadatomi kn-aut-name=万治忠福 kn-aut-sei=万治 kn-aut-mei=忠福 aut-affil-num=5 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=6 ORCID= en-aut-name=TsurumiTetsuya en-aut-sei=Tsurumi en-aut-mei=Tetsuya kn-aut-name=鶴見哲也 kn-aut-sei=鶴見 kn-aut-mei=哲也 aut-affil-num=7 ORCID= en-aut-name=FujiiYasuhisa en-aut-sei=Fujii en-aut-mei=Yasuhisa kn-aut-name=藤井靖久 kn-aut-sei=藤井 kn-aut-mei=靖久 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所温泉内科学部門 affil-num=2 en-affil= kn-affil=岡山大学温泉研究所温泉内科学部門 affil-num=3 en-affil= kn-affil=岡山大学温泉研究所温泉内科学部門 affil-num=4 en-affil= kn-affil=岡山大学温泉研究所温泉内科学部門 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=7 en-affil= kn-affil=愛媛県立中央病院内科 affil-num=8 en-affil= kn-affil=愛媛県立中央病院内科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=57 end-page=60 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Role of endoscopic elimination of protein plug in the treatment of chronic pancreatitis kn-title=内視鏡的純粋膵液採取による慢性膵炎の治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Endoscopic aspiration of pure pancreatic juice (ppj) was performed on 65 patients with chronic pancreatitis (cp) or suspected CP primarily for evaluating the validity of biochemical and physiochemical analysis of PPJ in the study of pathogenesis, pathophysiology and diagnosis of CP. PPJ was collected from within the main pancreatic duct by endoscopic retrograde catheterization of the papilla. With increasing experience, it has been revealed that various numbers of protein plugs are contained in PPJ obteined from patients with CP or suspected CP and that endoscopic elimination of protein plugs can provide them with dramatic relief from abdominal pain and back pain. The purpose of this report is to evaluate the role of endoscopic elimination of protein plugs in the treatment of CP. The following conclusions were obteined: (1) endoscopic elimination of protein plugs from within the pancreatic duct is useful. at least on a short-term basis, for relieving abdominal pain and back pain in one-forth of patients with CP or suspected CP; (2) this procedure can be an effective therapeutic tool in selected cases of CP or suspected CP where no prominent stenotic lesions are noted in the major pancreatic duct system and abstinence from alcohol bevarage is strictly observed. en-copyright= kn-copyright= en-aut-name=TanakaJuntaro en-aut-sei=Tanaka en-aut-mei=Juntaro kn-aut-name=田中淳太郎 kn-aut-sei=田中 kn-aut-mei=淳太郎 aut-affil-num=1 ORCID= en-aut-name=TakedaMasahiko en-aut-sei=Takeda en-aut-mei=Masahiko kn-aut-name=武田正彦 kn-aut-sei=武田 kn-aut-mei=正彦 aut-affil-num=2 ORCID= en-aut-name=TakasugiKiyoshi en-aut-sei=Takasugi en-aut-mei=Kiyoshi kn-aut-name=高杉潔 kn-aut-sei=高杉 kn-aut-mei=潔 aut-affil-num=3 ORCID= en-aut-name=HaradaHideo en-aut-sei=Harada en-aut-mei=Hideo kn-aut-name=原田英雄 kn-aut-sei=原田 kn-aut-mei=英雄 aut-affil-num=4 ORCID= en-aut-name=ManjiTadatomi en-aut-sei=Manji en-aut-mei=Tadatomi kn-aut-name=万治忠福 kn-aut-sei=万治 kn-aut-mei=忠福 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所 affil-num=2 en-affil= kn-affil=岡山大学温泉研究所 affil-num=3 en-affil= kn-affil=岡山大学温泉研究所 affil-num=4 en-affil= kn-affil=岡山大学温泉研究所 affil-num=5 en-affil= kn-affil=岡山大学医学部附属三朝分院 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=9 end-page=11 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Hypnotic effect of the peloid therapy applied on the right hypochondrium in reference to plasma L-tryptophan kn-title=右季肋部鉱泥湿布療法の催眠効果―血漿L-トリプトファンとの関連― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Based on the EEG-observation of falling asleep when patients are under peloid therapy applied on the right hypochondrium, following assumption is made to clarify the mechanism of inducing sleep. While patients are under the peloid therapy, some chemical substance will be produced in circulating blood; L-tryptophan, an essential amino acid and a precursor of serotonin, gets over a blood-brain barrier easily to induce sleep. Six healthy volunteers, each sex by threes, were selected to apply peloid pack on the right hypochondrium for 30 minutes following 12-hour fasting. Significant increase in plasma L-tryptophan level was obtained in the clinical experiment. It is speculated from the preliminary data that L-tryptophan increased by the peloid therapy may possibly act as a specific physiological hypnotics. en-copyright= kn-copyright= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=1 ORCID= en-aut-name=KomotoJunko en-aut-sei=Komoto en-aut-mei=Junko kn-aut-name=古元順子 kn-aut-sei=古元 kn-aut-mei=順子 aut-affil-num=2 ORCID= en-aut-name=KomotoYoshiaki en-aut-sei=Komoto en-aut-mei=Yoshiaki kn-aut-name=古元嘉昭 kn-aut-sei=古元 kn-aut-mei=嘉昭 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院リ-ビリテーション部 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=奥付 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=Institute for Thermal Spring Research, Okayama University en-aut-sei=Institute for Thermal Spring Research, Okayama University en-aut-mei= kn-aut-name=岡山大学温泉研究所 kn-aut-sei=岡山大学温泉研究所 kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=1 end-page=8 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Determination of ferritin in serum and in synovial fluids of patients with rheumatoid arthritis kn-title=慢性関節リウマチ患者の血清および関節液中のフェリチンの測定について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ferritin in sera and in synovial fluids were determined by method of immunoradiometric assay (IRMA) and of radioimmunoassay (RIA). These methods have been proved to be reproducible. The coefficient variation was 7.4 to 9.9% in IRMA and 5.6 to 8.0% in RIA. There were a good correlation between methods of IRMA and of RIA (r=0.989). The mean recovery rate of ferritin in serum was 101.2% in IRMA and 101.0% in RIA, respectively. The determination of serum ferritin revealed a 16% reduction in average after preservation at -20℃ during over 100 days. The levels of serum ferritin in healthy controls were 131.4±52.1 ng/ml in 34 males and 58.4±39.9 ng/ml in 38 females. The sex differences were statisticalIy significant (p<0.01). Ferritin levels were shown to be below 30 ng/ml (the state of iron deficiency) in 2 of 34 (5.9%) males and in 8 of 38 (21%) females of healthy controls. The levels of serum ferritin in patients with rheumatoid arthritis (RA) were 337.0±293.4ng/ml in 10 males and 181.4±329.9ng/ml in 25 females. The serum ferritin in RA was significantly higher than in healthy controls of both sexes. The levels of ferritin in synovial fluids of patients with 14 RA and with 12 osteoarthritis were 2894±3017 ng/ml and 1429±1005 ng/ml, and no differences were observed in both groups. en-copyright= kn-copyright= en-aut-name=FurunoKatsushi en-aut-sei=Furuno en-aut-mei=Katsushi kn-aut-name=古野勝志 kn-aut-sei=古野 kn-aut-mei=勝志 aut-affil-num=1 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=2 ORCID= en-aut-name=IrinoShozo en-aut-sei=Irino en-aut-mei=Shozo kn-aut-name=入野昭三 kn-aut-sei=入野 kn-aut-mei=昭三 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=35 end-page=43 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical effects of swimming training in a hot spring pool on bronchial asthma kn-title=気管支喘息における温泉プールによる運動浴の臨床効果について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Five severe bronchial asthma patients with glucocorticoid therapy have had free swimming training in the hot spring pool at Misasa Medical Branch. The clinical effect of the swimming training was evaluated after 3 months' training. 1. A slight increase in pulse rate and blood pressure was observed immediately after 30 minutes, swimming, although no significant increase in the two parameters was shown 30 min. after the training. 2. No significant fall in ventilatory function tests such as % FVC, FEV(1.0)%, V(50) and V(25) was demonstrated following the swimming training in a hot spring pool. The results suggest that the free swimming training in a hot spring pool does not induce bronchoconstriction. 3. Clinical efficacy of the swimming training on bronchial asthma was evaluated according to a treatment score, an attack score and an asthmatic score. These scores were decreased during the swimming training. The results obtained in this study showed that free swimming training in a hot spring pool is one of the most suitable therapies for severe bronchial asthma patients. en-copyright= kn-copyright= en-aut-name=TanizakiYoshiro en-aut-sei=Tanizaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=1 ORCID= en-aut-name=KomagoeHaruki en-aut-sei=Komagoe en-aut-mei=Haruki kn-aut-name=駒越春樹 kn-aut-sei=駒越 kn-aut-mei=春樹 aut-affil-num=2 ORCID= en-aut-name=SudoMichiyasu en-aut-sei=Sudo en-aut-mei=Michiyasu kn-aut-name=周藤真康 kn-aut-sei=周藤 kn-aut-mei=真康 aut-affil-num=3 ORCID= en-aut-name=MurashimaMakoto en-aut-sei=Murashima en-aut-mei=Makoto kn-aut-name=村嶋誠 kn-aut-sei=村嶋 kn-aut-mei=誠 aut-affil-num=4 ORCID= en-aut-name=OkadaChiharu en-aut-sei=Okada en-aut-mei=Chiharu kn-aut-name=岡田千春 kn-aut-sei=岡田 kn-aut-mei=千春 aut-affil-num=5 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=6 ORCID= en-aut-name=KobashiHidetoshi en-aut-sei=Kobashi en-aut-mei=Hidetoshi kn-aut-name=小橋秀敏 kn-aut-sei=小橋 kn-aut-mei=秀敏 aut-affil-num=7 ORCID= en-aut-name=TadaShinya en-aut-sei=Tada en-aut-mei=Shinya kn-aut-name=多田慎也 kn-aut-sei=多田 kn-aut-mei=慎也 aut-affil-num=8 ORCID= en-aut-name=KimuraIkuro en-aut-sei=Kimura en-aut-mei=Ikuro kn-aut-name=木村郁郎 kn-aut-sei=木村 kn-aut-mei=郁郎 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=7 en-affil= kn-affil=岡山大学医学部第2内科 affil-num=8 en-affil= kn-affil=岡山大学医学部第2内科 affil-num=9 en-affil= kn-affil=岡山大学医学部第2内科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=51 end-page=55 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical problems of long-term steroid regimen for bronchial asthma, with reference to steroid-dependent cases kn-title=気管支喘息における運動浴前後のventilatory　functionの変動 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Adverse side effects of steroid therapy were investigated in 32 asthmatic patients. Thirty-two patients were classified into three groups according to steroid therapy for the past five years; group 1 has been treated with continuous steroid therapy, group 2 with occasional steroid therapy and group 3 without steroid therapy. The results were as follows. 1. Group 1 showed a low level of serum cortisol at 8-9 a. m. The serum concentration of cortisol in patients with daily steroid regimen was lower as compared to that in patients with alternateday steroid therapy. 2. The daily profile of serum cortisol was low in the steroid dependent asthmatic patients, and little increase of serum cortisol level after the administration of prednisolone was shown in group 1. 3. Serum IgG and IgM levels were significantly low in steroid dependent asthmatic patients. 4. The level of serum potassium was low in group 1. en-copyright= kn-copyright= en-aut-name=SudoMichiyasu en-aut-sei=Sudo en-aut-mei=Michiyasu kn-aut-name=周藤真康 kn-aut-sei=周藤 kn-aut-mei=真康 aut-affil-num=1 ORCID= en-aut-name=KomagoeHaruki en-aut-sei=Komagoe en-aut-mei=Haruki kn-aut-name=駒越春樹 kn-aut-sei=駒越 kn-aut-mei=春樹 aut-affil-num=2 ORCID= en-aut-name=MurashimaMakoto en-aut-sei=Murashima en-aut-mei=Makoto kn-aut-name=村嶋誠 kn-aut-sei=村嶋 kn-aut-mei=誠 aut-affil-num=3 ORCID= en-aut-name=OkadaChiharu en-aut-sei=Okada en-aut-mei=Chiharu kn-aut-name=岡田千春 kn-aut-sei=岡田 kn-aut-mei=千春 aut-affil-num=4 ORCID= en-aut-name=TanisakiYoshiro en-aut-sei=Tanisaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=5 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=6 ORCID= en-aut-name=ShiotaYutaro en-aut-sei=Shiota en-aut-mei=Yutaro kn-aut-name=塩田雄太郎 kn-aut-sei=塩田 kn-aut-mei=雄太郎 aut-affil-num=7 ORCID= en-aut-name=KimuraIkuro en-aut-sei=Kimura en-aut-mei=Ikuro kn-aut-name=木村郁郎 kn-aut-sei=木村 kn-aut-mei=郁郎 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=7 en-affil= kn-affil=岡山大学医学部第二内科 affil-num=8 en-affil= kn-affil=岡山大学医学部第二内科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=45 end-page=49 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical problems of long-term steroid regimen for bronchial asthma, with reference to steroid-dependent cases kn-title=気管支喘息のステロイド療法における2,3の問題点について―ステロイド依存性喘息を中心に― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Adverse side effects of steroid therapy were investigated in 32 asthmatic patients. Thirty-two patients were classified into three groups according to steroid therapy for the past five years; group 1 has been treated with continuous steroid therapy, group 2 with occasional steroid therapy and group 3 without steroid therapy. The results were as follows. 1. Group 1 showed a low level of serum cortisol at 8-9 a. m. The serum concentration of cortisol in patients with daily steroid regimen was lower as compared to that in patients with alternateday steroid therapy. 2. The daily profile of serum cortisol was low in the steroid dependent asthmatic patients, and little increase of serum cortisol level after the administration of prednisolone was shown in group 1. 3. Serum IgG and IgM levels were significantly low in steroid dependent asthmatic patients. 4. The level of serum potassium was low in group 1. en-copyright= kn-copyright= en-aut-name=KomagoeHaruki en-aut-sei=Komagoe en-aut-mei=Haruki kn-aut-name=駒越春樹 kn-aut-sei=駒越 kn-aut-mei=春樹 aut-affil-num=1 ORCID= en-aut-name=SudoMichiyasu en-aut-sei=Sudo en-aut-mei=Michiyasu kn-aut-name=周藤真康 kn-aut-sei=周藤 kn-aut-mei=真康 aut-affil-num=2 ORCID= en-aut-name=OkadaChiharu en-aut-sei=Okada en-aut-mei=Chiharu kn-aut-name=岡田千春 kn-aut-sei=岡田 kn-aut-mei=千春 aut-affil-num=3 ORCID= en-aut-name=TanizakiYoshiro en-aut-sei=Tanizaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=4 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=5 ORCID= en-aut-name=KitaniHikaru en-aut-sei=Kitani en-aut-mei=Hikaru kn-aut-name=貴谷光 kn-aut-sei=貴谷 kn-aut-mei=光 aut-affil-num=6 ORCID= en-aut-name=GodaYoshinori en-aut-sei=Goda en-aut-mei=Yoshinori kn-aut-name=合田吉徳 kn-aut-sei=合田 kn-aut-mei=吉徳 aut-affil-num=7 ORCID= en-aut-name=TadaShinya en-aut-sei=Tada en-aut-mei=Shinya kn-aut-name=多田慎也 kn-aut-sei=多田 kn-aut-mei=慎也 aut-affil-num=8 ORCID= en-aut-name=TakahashiKiyoshi en-aut-sei=Takahashi en-aut-mei=Kiyoshi kn-aut-name=高橋清 kn-aut-sei=高橋 kn-aut-mei=清 aut-affil-num=9 ORCID= en-aut-name=KimuraIkuro en-aut-sei=Kimura en-aut-mei=Ikuro kn-aut-name=木村郁郎 kn-aut-sei=木村 kn-aut-mei=郁郎 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部第2内科 affil-num=7 en-affil= kn-affil=岡山大学医学部第2内科 affil-num=8 en-affil= kn-affil=岡山大学医学部第2内科 affil-num=9 en-affil= kn-affil=岡山大学医学部第2内科 affil-num=10 en-affil= kn-affil=岡山大学医学部第2内科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=17 end-page=21 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A psychosomatic study of anorexia nervosa, with particular attention to the deveropmental aspect. Part 2 Female adult cases of anorexia nervosa kn-title=発達的観点からみた神経性食欲不振症の心身医学的研究 第2報 成人期女子例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Following the previous report in which analysis of two female adolescent cases was described, two female adult cases were presented in this report. The summery as follows: 1) Onset of two cases is in their early twenties, coincided with their inter-personal conflicts at work and in the family in law. Morbid condition of each case has been unchanged todate, over the age of fourty; case 1 presents chronic anorexia with bulimia and case 2 presents chronic anorexia without bulimia. 2) There was the evidence of immaturity of heterosexual object-relationship which originated from the disturbed father-daughter interaction, together with the evidence of a disturbed female identification as seen in the adolescent group. 3) Self-starvation of each case appears to have similar psychological meaning as seen in the adolescent cases; retaliation towards the mother of each patient and compensatory aim in the dependancy need. However, keeping a pride in pubertal competitions such as a pursuit in the slim body image may shift to a phobic avoidance of gastro-intestinal dyscomfort. Eventully poor motivation for treatment aimed at tackling the adolescent maturational problems seems to be the core of the disorder. en-copyright= kn-copyright= en-aut-name=KomotoJunko en-aut-sei=Komoto en-aut-mei=Junko kn-aut-name=古元順子 kn-aut-sei=古元 kn-aut-mei=順子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院神経精神料 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=目次 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=Institute for Thermal Spring Research, Okayama University en-aut-sei=Institute for Thermal Spring Research, Okayama University en-aut-mei= kn-aut-name=岡山大学温泉研究所 kn-aut-sei=岡山大学温泉研究所 kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=13 end-page=16 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Anorexia nervosa in the male report on 5 cases kn-title=神経性食欲不振症の5男子例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The case histories of 5 males diagnosed as anorexia nervosa were presented. The summary as follows : (1) 2 pre-adolescent cases; Onset of self-starvation of each case is coincided with separation from each mother, with the psychological meaning of retaliation towards the mother of each patient and of compensatory gain in dependancy need. Rorschach test of either case presents the ambivalent attitude towards each mother, of love and hate. (2) An adolescent case; Onset of self-starvation is coincided with competitious hyperactivity in sport, with some compensatory gain in dependancy need and with keeping pride in pubertal competition, including a pursuit in the slim body image. Rorschach test presents pausity of masculinity. (3) A young case; Onset of self-starvation is coincided with separation from his mother, as seen in pre-adolescent case, with phobic avoidance of protenuria from which he suffered previously. Rorschach test indicates paucity of masculinity. (4) An adult case (married); Onset of self-starvation is coincided with his conflicts at work and home, with the psychological meaning of keeping him from undoing duties as a worker and as a husband. Rorschach test presents mother-identification instead of father-identification. en-copyright= kn-copyright= en-aut-name=KomotoJunko en-aut-sei=Komoto en-aut-mei=Junko kn-aut-name=古元順子 kn-aut-sei=古元 kn-aut-mei=順子 aut-affil-num=1 ORCID= en-aut-name=YasumotoIkuko en-aut-sei=Yasumoto en-aut-mei=Ikuko kn-aut-name=安本生子 kn-aut-sei=安本 kn-aut-mei=生子 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院神経精神科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院神経精神科 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=表紙 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=Institute for Thermal Spring Research, Okayama University en-aut-sei=Institute for Thermal Spring Research, Okayama University en-aut-mei= kn-aut-name=岡山大学温泉研究所 kn-aut-sei=岡山大学温泉研究所 kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=裏表紙 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=Institute for Thermal Spring Research, Okayama University en-aut-sei=Institute for Thermal Spring Research, Okayama University en-aut-mei= kn-aut-name=岡山大学温泉研究所 kn-aut-sei=岡山大学温泉研究所 kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil= END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=67 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=On the Munyeijin potassium salt deposits in Yunnan Province, People's Republic of China kn-title=雲南省? 野井カリ塩鉱床の古水文地質について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In Langping-Simao basins of Southwestern Yunnan Province, a number of salt deposits and salt springs are distributed (Fig. 1). The salt-bearing formations are sandstones, silt and mudstones of the Cretaceous to Paleogene ages, although the ages of the potassium-salts deposits seem to be younger. The Munyeijin potassium deposit was found on the eastern side of the Simao basin in early nineteen sixties. Although the salt deposit has been strongly deformed by tectonic movements (Fig. 2), the deposit has salt-dome structure and three depositional stages have been identified in each cycle of depositional sequence. They are, from the bottom to the top, red salts, black and white salts and carnallite-bearing clayey rocks (see Fig. 3). The red colour of the bottom zone is due to globular debris of silt in the red salts, whereas the top clayey rocks are high in organic materials, being characteristic of the residue of the last stage evaporation of a salt lake. Potassium salt is found in all the three zones, filling up the grain gaps of sodium chloride crystals or running through salt beds in veins and veinlets, although the black-white salts are the most fertile in potassium and have been mined for commercial use. Small amounts of carbonates and sulfates (gypsum and anhydrite) also exist as fine, dispersed grains. Thin layers of gypsum are not uncommon in dark portions of the red and black-white salts. Tachhydrite (CaCl(2)・2MgCl(2)・6H(2)O) is also observed in the top clayey deposits. From the field observation, geological, mineralogical, and geochemical considerations, the paleohydrogeological environments which led to the formation of potassium-rich salt deposits at Munyeijin are reconstructed as follows: 1) The depositional stage of the carnallite-bearing sediments: This is the last stage of evaporation of a salt lake. The sediments would have had up to 80 vol. % interstitial waters saturated with carnallite and sylvite. 2) Diagenetic stage: The carnallite-clay deposits were covered by younger salt deposits and the pore water was gradually squeezed out by compression. The pore water penetrated into the underlying sodium chloride deposits, where the pore water precipitated sylvite as the sodium salts were essentially devoid of potassium. Because the pore water contained organic materials (Table 2), the sylvite precipitates were dark in colour. 3) Tectonic stage: The Langping and Simao basins are lined along the Sanjian tectonic belts. The tectonic activity which presumably started in Eocene must be responsible for the intense deformation of the salt beds. Enrichment of potassium along the axis of folding and the anhydrite formation with the axis of crystallization tilted to the plane of salt beds are some of the important paleohydrogeological results of such movements. Several lines of evidence strongly suggest that hydrothermal activity took place widely in Munyejin basin during this stage. The origin of the potassium-bearing brines has been debated in China since the discovery of the deposits. Many lines of evidence suggest it be of marine origin. However, the presence of tachhydrite in the carnallite-bearing clayey deposits requires some additional source(s) of calcium in addition to seawater. The highly saline groundwaters in Triassic through Jurassic formations of Sichuan Province often are rich in Ca(2+) as well as Mg(2+) and K(+) as some examples are shown in Table 3. If such saline ground waters flew into a salt lake and was subjected to evaporation, calcium-bearing salts such as tachhydrite may form at the last stage deposit of the lake. The origin of such groundwaters is an interesting problem to be studied in future. en-copyright= kn-copyright= en-aut-name=JiaShuyuan en-aut-sei=Jia en-aut-mei=Shuyuan kn-aut-name=賈疏源 kn-aut-sei=賈 kn-aut-mei=疏源 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=成都地質学院水文地質工程地質学部 END