JaLCDOI 10.18926/40350
Title Alternative TWO CACES OF CHRONIC FOUDOL POISONING
FullText URL 013_044_050.pdf
Author Onda, Sakue| Kishida, Senzo|
Abstract Two cases of chronic Folidol intoxication were described. Both patients complained of oppressive feeling in upper abdomen, breast and head, since exposure to Folidol-spray. Case 1. A farmer aged 21. Two months after Folidol-spraying, investigation revealed a slight fever, a slight hyperchromic anaemia with relative lymphocytosis, achylia gafotrica, a decreased concentration in bile with a few gall-sands and an occasional tenderness on gall-bladder. Bromsulfalein test slightly positive (8%). A hypoglycaemia, hypotension, high sensitivity to pilocarpine, vanished patellar and Achilles tendon reflexes and a positive Sawada test in urine were also observed. None of the treatments given showed a favourable result. Case 2. A farmer, aged 27. Three months after Folidol-spraying, investigation revealed a slight fever, a hypochromic anaemia and a decrease in serum-cholinesterase activity (40%).
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 44
End Page 50
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 40017532456
JaLCDOI 10.18926/40349
Title Alternative COPPER AND ZINC CONTENT OF BLOOD AFTER INTRAVENOUS INJECTION OF DITHIZONE OR OXIN IN RABBIT
FullText URL pitsr_013_042_043.pdf
Author Ashizawa, Takashi|
Abstract Okamoto found that not only alloxan but also dithizone or oxin can produce diabetes in the test animals and proposed a zinc theory of diabetes. As dithizone and oxin react not only with zinc but also with many other metals, such as copper, nickel, cobalt, bismuth, silver etc, the author investigated the copper and zinc content of blood after intravenous administration of dithizone (100 mg per kg of bodyweight) or oxin (50 mg per kg of bodyweight) to rabbit by chromatographic method devised by the author. Both zinc and copper in blood decreased soon after the injection of the above-mentioned reagents and recovered only slowly after 24 - 48 hours.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 42
End Page 43
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002484882
JaLCDOI 10.18926/40348
Title Alternative MEDICAL STUDIES ON CHONDROITIN SULFATE (III)
FullText URL 013_036_041.pdf
Author Oshima, Yoshio| Sotozono, Masazumi|
Abstract 2-5cc. of 1% Rodium chondroitin-sulfate solution subcutaneouRly or 2cc. of 5% solution intraveneously was administered to 37 cares of painful disorders such as headache, backache or arthralgia. A marked improvement was obtained in 12 cares and a moderate result was seen in 16 cases. No definite change was proved concerning blood pressure in the patients and detoxicating effect in animal experiment.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 36
End Page 41
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 40017532453
JaLCDOI 10.18926/40347
Title Alternative KLINISCHE UND EXPERIMENTELLE UNTERSUCHUNGEN ÜBER DIE WIRKUNG VON THERMALBÄDERN AUF DIE SEXUALFUNKTION VON FRAUEN (5) UNTERSUCHUNGEN ÜBER DIE BEEINFLUSSUNG DER QUAINTITÄT DER ACETYLCHOLINARTIGEN SUBSTANZ IN ZWISCHENHIRN DER RATTE NACH THERMALBADE
FullText URL pitsr_013_031_035.pdf
Author Tanaka, Yosinori|
Abstract In frühen Arbeiten habe ich den Nachweiss erbracht, dass Thermalbädern den Brunstzyklus der weiblichen Ratten regelmässig werden lassen, und diese Erscheinung auf die Steigerung der Hupophysenvorderlappenfunktion zurückzuführen ist. Andererseits ist es bekannt, dass Zunahme der acetylcholinartigen Substanz der Zwischenhirn die Steigerung der Hypophysenvorderlappenfunktion mit sich bringt. Unter diesen Gesichtspunkten wurden die Bestimmnngen der acetylcholinartigen Substanz in zwischenhirn der Ratte nach Thermalbade vorgennommen. 47 männliche Ratte wurden in Misasa Therma - radioaktive Thermen - 10 Minuten lang bei 42°C gebadet, dann in 4 Gruppen geteilt, und εfort, an 30., 60., und 90. Minute nach dem Bade wurde diese Subfotanz nach Methode von M. rectus abdeminis der Frosch bestimmt, und mit kontrolltiere verglichen. Es wurde festgestellt, dass freie acetylcholinartige Snbstanz sich an 30. Minute nach dem Bade vermehrte, aber an anderen Zeiten kein statistisch signifikanter Unterschied zwischen Badgruppe lmd Kontrollgruppre hinisichtlich des Gehalt der freien, kombinierten und gesamten acetylcholinartigen Subtanz war. Die Tatsachen lassen daran denken, dass Zunahme der freien acetylcholinartigen Substanz in Zwischenhirn, die gescbah nach dem Thermalbade, sich an Verbesserung der Sexualfunktion von Thermalbädern vielleicht beteiligt. Üher diese Erscheinungen werden die Rolle der Radiumemanation im Thermalwasser und Unterschied zwischen Thermalwasser und Süsswasser in künftigen Arbeiten untersucht werden.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 31
End Page 35
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 120002484881
JaLCDOI 10.18926/40346
Title Alternative STUDIES ON SERUM MUCOPROTEIN (2) RELATION BETWEEN SERUM MUCOPROTEIN LEVEL AND DIFFERENTIAL AGGLUTINATION TEST FOR RHEUMATOID ARTHRITIS. AN EXPERIMENTAL AND CLINICAL STUDY
FullText URL 013_024_030.pdf
Author Ueda, Yoshio|
Abstract (1) Mucoprotein level in serum and agglutination reaction by Rose for rheumatoid arthritis were measured in 40 cases of rheumatoid arthritis, cancer, pulmonary tuberculosis or liver disease (mostly acute hepatitis). A raised titer of mucoprotein was often observed in cancer, and a marked rise in agglutination titer was often proved in rheumatoid arthritis. But no significant correlation was proved between the serum mucoprotein level and agglutination test in patients. (2) [n animal experiment an inereased agglutination titer was caused by sensitization with egg albumin, Arthus' s phenomenon, anaphylactic, shock, thermal spring bath, X-ray irradiation, blocking of reticuloendothelial system, liver injuries, injection of A. C. T. H., adrenaline, atropin or pilocarpin. A simultaneoas rise in serum mucoprotein level was observed after sensitization, thermal bath, X-ray irradiation, administmtion of chloroform, injection of toxic agents to vegetative nerve system. And a significant positive linear correlation was proved between the serum mucoprotein level and agglutination titer in the animal experiment on the whole. But a dissociation in this relation was observed during anaphylactic shok. Namely serum mucoprotein level tended to fall soon after the reinjection, while the agglutination titer rose higher temporarily and then both showed a tendency to decrease.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 24
End Page 30
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 40017532450
JaLCDOI 10.18926/40345
Title Alternative BALNEOLOGICAL STUDIES USING RADIOACTIVE ISOTOPES (3)
FullText URL pitsr_013_018_023.pdf
Author Yokota, Takeo| Ashizawa, Takashi|
Abstract By using labelled sodium sulfate or calcium sulfate (sulfate containing S(35)) the transition of sulfate ion into the body across the skin was investigated soon after taking a bath in sodium sulfate or calcium sulfate solution under varing conditions. Mice were used for experiments. The percutaneous absorption of sulfate ion proved to decrease gradually in the course of serial baths in sodium sulfate solntion and was accelerated by making a fresh burn on the skin of the bathed animals, but it showed a tendency to decrease as the wound became more and more healed. The application of basic dye to the skin (e.g. 1% methylenblue or 1% fuchsin solution) increased the transition of sulfate ion into the test animal. Little difference was proved between the bath in sodium sulfate and calcium sulfate solution with respect to the penetration of sulfate ion. Passage of sulfate ion from the bath water through the skin was a little promoted by the use of sodium sulfate solution than by the use of calcium sulfate solution.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 18
End Page 23
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 120002484880
JaLCDOI 10.18926/40344
Title Alternative STUDIES ON VITRIOL SPRINGS (4) ON THE COPPER, ZINC, NICKEL, AND COBALT CONTENTS OF BLOOD AFTER THE INTERNAL USE OF A VITRIOL WATER
FullText URL 013_015_017.pdf
Author Oshima, Yoshio| Ashizawa, Takashi|
Abstract Sotozono proved that the administration of daily 20cc of Fujino Mineral Water (an acid vitriol water containing copper, zinc, nickel and cobalt) has a remarkably beneficial effect on several kinds of hypochromic anemia. It contains 9.56gms of iron, 0.007gm of zinc, 0.005gm of copper 0.001gm of nickel, and 0.006gm of cobalt in one liter. 20 - 40cc of Fujino water was diluted 5 - 10 fold with plain water and administered to the fasting patients perorally. Blood samples were taken from cubital vein before, 1, 2, 4, 6, 24, 48, and 72 hours after the intake of the vitriol water. Copper, zinc, nickel and cobalt contents of the blood samples were measured by Ashizawa' s dithizone- chromatographic method. It was shown that copper, nickel, and cobalt contents of blood rose unexpectedly high temporarily, in a manner that did not correspond to their amount in the given mineral water. So that the mobilization of copper, nickel, and cobalt in the body after the intake of the mineral IVrter was susrected. Zinc content of blood showed no constant tendency.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 15
End Page 17
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002484879
JaLCDOI 10.18926/40343
Title Alternative STUDIES ON VITRIOL SPRINGS (3) EFFECT OF THE INTERNAL USE OF VITRIOL WATER OF FUJINO ON THE GASTRIC ACIDITY
FullText URL pitsr_013_009_014.pdf
Author Morinaga, Hiroshi|
Abstract Fujino Spring is the foremost acid vitriol spring of Japan in ferrous and ferric ion contents. Six years ago the author reported that its internal use had an remarkable hemopoietic effect on hypochromic anemia and delayed the curve of alimentary hyperglycemia in rabbit. Twenty ml. of this vitriol water was diluted with plain water to two hundred ml. and was given to twenty one patients by stomach tube at 37°C. Gastric acidity of the patients was measured at 30 minutes intervals during the following 150 minutes after the administration of the water. In six cases of normal acidity no significant difference was proved between the effects of the mineral water and of caffein control (0.2g. in 200 ml.). In six cases of hyperacidity it seemed that the vitriol water decreased in the acidity curve compared with control. In nine patients of hypo- and anacidity both free and total acidity curve was elevated by the use of the mineral water compared with caffein control. The internal use of Fujino Spring in moderate dilution with plain water regulated the gastric acidity.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 9
End Page 14
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002484879
JaLCDOI 10.18926/40342
Title Alternative ON THE EXISTENCE OF RADIUM B, RADIUM C AND THORIUM B IN MISASA HOT SPRINGS
FullText URL pitsr_013_005_008.pdf
Author Sato, Mitsuo|
Abstract The author tried to measure RaB, RaC and ThB in the hot spring waters using G-M counter and proved the existence of RaB and ThB in Misasa Hot Springs. To 100 liters of spring water ahout 20 gms of ferric chloride and then sodium hydroxide were added. Precipitate was dissolved in hydrochloric acid and after adding bismuth and lead, the solution was saturated with hydrogen sulfide. The precipitate of sulfides was filtered and ignited to ashes after drying. The β-activity of the ashes was measured by a mica-window type G-M counter with the recording circuits of scale of 16. Natural background was 50±5 connts per minutes. Six spring waters of Misasa, namely "Spring of Branch Laboratory", "Nakayu", "Gunze" "O-T-R", "Jwayu", and "Tsukiminoyu" were investigated. RaB was detected in all samples. ThB was found only in "Gunze" and "O-T-R". ThB content of "Gunze" was estimated, to be roughly 1×10(-12) Curie units per liter.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 5
End Page 8
ISSN 0369-7142
language English
File Version publisher
NAID 120002484878
JaLCDOI 10.18926/40341
FullText URL pitsr_013_001_005.pdf
Author Umemoto, Shunji|
Abstract Various colormetric methods for determining magnesium in natural waters have been studied, and the methods using 8-oxyquinolin, ammonium molybdate and titan yellow were studied most frequently(1)), following the studies on the interfering ions(2)). Brilliant yellow(3)), l-amino-2-naphthol-6-sulfonic acid(4)) and other new reagents were also used. E. D. T. A. was used, but the determination by using this reagent is not exact. Present reagent already reported by T. Ashizawa(5)), magneson II, is insoluble in water, soluble in alkali and hardly soluble in ethanol. In the existence of magnesium ion, the color of solution varies from pink-violet (in alkali) and orange (in ethanol) to blue-violet. This variation of color was evaluated photometrically by Shimadzu photoelectric spectrophotometer, and moreover the grades of interference by interfering ions were clarified.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 1
End Page 5
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language English
File Version publisher
NAID 120002484877
Author 岡山大学温泉研究所|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Oshima, Yoshio|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Seki, Masaji|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 大島 良雄|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 淸水 多栄|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Institute for Thermal Spring Research, Okayama University|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others