start-ver=1.4
cd-journal=joma
no-vol=2
cd-vols=
no-issue=7
article-no=
start-page=607
end-page=610
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110428
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Quantification of the orientations of pyrrolidine-based oxypeptide nucleic acid–DNA hybrid duplexes
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We describe the fluorescence quenching-based quantification of complementary parallel and antiparallel hybrids of DNAs with pyrrolidine-based oxypeptide nucleic acids (POPNAs). When BODIPY-modified DNAs as fluorescent probe formed hybrids with complementary POPNAs, fluorescence of the BODIPY was effectively quenched by the guanine unit and the Lys unit on the POPNAs. The orientations of hybrids of POPNA with DNA were estimated by the quenching efficiencies of two BODIPY-modified DNAs . As a result, we clarified that configurations of POPNAs affect the extent of orientation of the hybrid duplexes.
en-copyright=
kn-copyright=

en-aut-name=KitamatsuMizuki
en-aut-sei=Kitamatsu
en-aut-mei=Mizuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=SisidoMasahiko
en-aut-sei=Sisido
en-aut-mei=Masahiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Medical and Bioengineering, Graduate School of Natural Science and Technology, Okayama University

affil-num=2
en-affil=
kn-affil=
END