start-ver=1.4
cd-journal=joma
no-vol=164
cd-vols=
no-issue=1
article-no=
start-page=552
end-page=555
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=2-Diphenylphosphanyl-4-pyridyl(dimethyl) amine as an effective ligand for the ruthenium(II) complex catalyzed homogeneous hydration of nitriles under neutral conditions
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=New homogeneous catalyst comprised of [Ru(methallyl)(2)(cod)] (cod = 1,5-cyclooctadiene) (1) and 2-diphenylphosphanyl-4-pyridyl(dimethyl) amine (2) is shown to efficiently catalyze the hydration of various nitriles under neutral conditions. The hydration proceeds in the presence of 0.5 mol% of the ruthenium catalyst at 80 degrees C in 1,2-dimethoxyethane solution and the corresponding amide is obtained within few hours without the formation of by products. Comparison of some phosphine ligands for the hydration reveals that the dimethylamino moiety of 2 improves the catalytic performance dramatically.
en-copyright=
kn-copyright=

en-aut-name=MuranakaMakoto
en-aut-sei=Muranaka
en-aut-mei=Makoto
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=HyodoIsao
en-aut-sei=Hyodo
en-aut-mei=Isao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=OkumuraWataru
en-aut-sei=Okumura
en-aut-mei=Wataru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=OshikiToshiyuki
en-aut-sei=Oshiki
en-aut-mei=Toshiyuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

affil-num=1
en-affil=
kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University

affil-num=2
en-affil=
kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University

affil-num=3
en-affil=
kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University

affil-num=4
en-affil=
kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University
en-keyword=Hydration
kn-keyword=Hydration
en-keyword=Nitrile
kn-keyword=Nitrile
en-keyword=Amides
kn-keyword=Amides
en-keyword=Homogeneous catalysis
kn-keyword=Homogeneous catalysis
en-keyword=Ruthenium
kn-keyword=Ruthenium
en-keyword=Phosphine
kn-keyword=Phosphine
END