JaLCDOI 10.18926/AMO/30386
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Author Zhao, Yi| Wang, Xiaoyan| Kawai, Motoko| Liu, Jiankang| Liu, Miao| Mori, Akitane|
Abstract <p>Chinese ant extract preparations (CAEP) are a Chinese traditional medicine which is mainly used as a health food or drink for the treatment of rheumatism, rheumatoid arthritis, chronic hepatitis, sexual hypofunction, and antiaging in China. The effects on free radicals were examined by electron spin resonance spectrometry using the spin trapping agent 5.5-dimethyl-1-pyrroline-1-oxide (DMPO). Superoxide radicals (3.35 x 10(15) spins/ml) were quenched 50% by the extract at 0.5 mg/ml. The CAEP extract at 0.7 mg/ml inhibited 50% of hydroxyl radicals (52.0 x 10(15) spins/ml) generated by the Fenton reaction. Against DPPH radical, the scavenging action of CAEP was observed at 1.8 mg/ml of the extract and 50% of the DPPH radicals (8.14 x 10(15) spins/ml) were quenched. In vitro tests showed that CAEP inhibited the production of thiobarbituric acid-reactive substances, an index of lipid peroxidation, in rat brain homogenate.</p>
Keywords free radical scavenger antioxidant hydroxyl radical superoxide radical lipid peroxidation
Amo Type Article
Published Date 1995-12
Publication Title Acta Medica Okayama
Volume volume49
Issue issue6
Publisher Okayama University Medical School
Start Page 275
End Page 279
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8770235
Web of Science KeyUT A1995TM84600001