JaLCDOI 10.18926/AMO/53555
FullText URL 69_4_197.pdf
Author Ishibashi, Naoki| Miyasho, Koji| Kitamura, Tetsuhisa| Ookuma, Takaaki| Kashitani, Nobuhiro| Beika, Nobuhiko| Yamashita, Takahiro| Ujike, Yoshihito|
Abstract We evaluated the hemodynamics and outcomes of septic shock (SS) patients who did not respond to fluid resuscitation, after treatment with or without intravenous calcium. We retrospectively collected information on 154 eligible SS patients who were admitted to Fukuyama City Hospital Emergency Medical Center and did not respond to fluid resuscitation. To compare their degree of hemodynamic impairment, we compared the changes in the vasoactive-inotropic score (VIS) in the calcium-treated group (n=112) and the noncalcium-treated group (n=42). We compared the length of stay in the intensive care unit (ICU) and hospital, in-hospital deaths, 28-day deaths, and changes in the Sequential Organ Failure Assessment score within 72h of ICU admission between the 2 groups. Changes in the VIS at 1h after the baseline time were significantly greater in the calcium-treated group than in the noncalcium-treated group (1.41 vs. -1.25, respectively;p<0.001). However, the changes in the VIS at 3, 6, 24, 48, and 72h did not differ between the 2 groups. The secondary outcomes also did not differ between the groups. Our findings indicate that calcium administered to SS patients might reduce their hemodynamic stabilization, but only for a short time after its administration.
Keywords hemodynamics calcium shock sepsis
Amo Type Original Article
Published Date 2015-08
Publication Title Acta Medica Okayama
Volume volume69
Issue issue4
Publisher Okayama University Medical School
Start Page 197
End Page 204
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 26289910
Web of Sience KeyUT 000365519100002
Author Yamashita, Takahiro|
Published Date 1988-01-20
Publication Title 岡山大学経済学会雑誌
Volume volume19
Issue issue3-4
Content Type Journal Article
Author Yamashita, Takahiro|
Published Date 1988-05-31
Publication Title 岡山大学経済学会雑誌
Volume volume20
Issue issue1
Content Type Journal Article