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ID 32371
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Author
Ida, Noriaki
Oda, Nobuo
Yoda, Tadao
Kiyama, Takashi
Abstract

1. The objective of this investigation was to test the influence of mammary cancer tissue extract on the induction of various tumors by urethan. Three strains of female mice, Balb/c, Zb and Db, were used in this experiment. 2. It was found that urethan was a multipotential carcinogen in the induction of (a) lung tumor, ovarian hemorrhagic cyst, and hemorrhagic lesions in various tissue in Balb/c mice, (b) lung tumor, hepatoma, leukemia, mammary cancer, Harderian gland tumor and hemorrhagic lesions in various tissues such as spleen, mesenteric lymphnode, liver and ovary in Zb strain, and (c) lung tumor, mediastinal lymphoma, leukemia, hepatoma and hemorrhagic lesions in the liver and ovary in Db mice. 3. Mammary cancer tissue extract seemed to have a promotive effect on the generalization of the mediastinal lymphoma induced by urethan in Db female mice.

Amo Type
Article
Published Date
1962-10
Publication Title
Acta Medicinae Okayama
Volume
volume16
Issue
issue5
Publisher
Okayama University Medical School
Start Page
253
End Page
264
NCID
AA00041342
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
NAID