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ID 42485
FullText URL
Thumnail 69_515.pdf 663 KB
Title Alternative
Studies on Alkylphosphate Poisoning Part II Studies on the Tissue Cholinesterase in Parathion Poisoning
Author
Yamada, Minoru
Abstract
The tissue cholinesterase (ChE) activity in normal rabbit was the highest in the central nervous system, and was high following descending order; liver, spleen, erythrocyte, lung, serum, gastrointestinal tract, kidney, heart and muscle. By a subcutaneous parathion injection, there occured the changes of ChE both in the tissues and blood as follows. 1) At the time of death caused by the administration of 100 mg/kg of parathion, the ChE in serum, erythrocyte and central nervous system were inhibited strongly than that in the others and the inhibition of liver ChE was the slightest. 2) On the case of the administration of 5 mg/kg of parathion, the inhibition of ChE was great in blood, slight in the liver and moderate in the central nervous system. On this case, the inhibition of ChE in the tissue was maximum after 6-12 hours, and the restoration of it was after 11 days, but in the kidney both were slower than the others.
Published Date
1957-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume69
Issue
issue2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
515
End Page
523
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/69/2/69_2_515/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright© 岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma