JaLCDOI 10.18926/AMO/31040
FullText URL fulltext.pdf
Author Yabe, Yoshiro| Matsumoto, Kyoko| Ogura, Hajime|
Abstract <p>To establish an experimental persistent infection of the brain with human adenoviruses, adenovirus type 6 (ad 6) was inoculated intracerebrally into young adult hamsters. Hamsters appeared languid for a few days after inoculation, but recovered rapidly. By cocultivation of tissue fragments with HeLa cells, ad 6 was always recovered from the brains of hamsters throughout their lives, as long as 29 months, indicating the establishment of a lifelong persistent infection. Except for the first few days after inoculation, however, attempts to recover virus by inoculation of tissue extracts onto HeLa cells or by cultivation of tissue fragments alone were unsuccessful.</p>
Keywords adenovirus type 6 persistent infection hamster brain
Amo Type Article
Published Date 1988-02
Publication Title Acta Medica Okayama
Volume volume42
Issue issue1
Publisher Okayama University Medical School
Start Page 45
End Page 47
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 3364214
Web of Science KeyUT A1988M237800008