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ID 17049
Eprint ID
17049
FullText URL
Thumnail 92_531.pdf 2.35 MB
Title Alternative
Histological studies of the lung in allergic respiratory responses Part Ⅱ. Histological investigations of the lung in experimentally sensitized animals
Author
Harada, Hiroshi
Abstract
Hypersensitivity pneumonitis and bronchial asthma were experimentally developed with adjuvant and aerosolized antigens used together and separately. Histological investigations of the lung were performed in several conditions depending on the use of adjuvant or antigens. The results were as follows. 1) In animals treated with BCG only, pulmonary histological findings such as granulomatous changes, small clusters of mononuclear cell accumulation, interstitial mononuclear cell infiltration and septal thickening were observed. Granulomatous changes in the condition consisted of predominant epithelioid cells. 2) In animals sensitized by aerosolized antigens only, marked histological changes such as cell infiltration around the alveolar septum and bronchiolar wall were observed in the use of Candida antigen. On the other hand, granuloma formation and cell infiltration around vascular wall were predominantly found in the use of Aspergillus antigens. 3) The incidence of granuloma formation and the degree of mononuclear cell infiltration tended to increase with the use of high concentration of antigen. 4) Histological findings such as granulomatous changes and cell infiltration were marked in the animals sensitized by both adjuvant and antigens.
Keywords
BCG
カンジダ
アスペルギルス
肉芽腫
実験的過敏性肺臓炎
Published Date
1980-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume92
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
531
End Page
544
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/92/3-4/92_3-4_531/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma