| JaLCDOI | 10.18926/AMO/32277 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Karakas, Zeynep| Agaoglu, Leyla| Biner, Betul| Devecioglu, Omer| Anak, Sema| Yalman, Nevin| Unuvar, Aysegul| Celik, Alaattin| Gedikoglu, Gunduz| |
| Abstract | <p>Fifty-one children (median age: 4.5 years; 4 months-16 years) diagnosed with rhabdomyosarcoma were treated in our center between 1980-1999. The primary sites were head and neck in 31.4%, the genito-urinary system in 21.6%, and extremities in 9.8% of the patients. The histopathologic subtypes were embryonal in 80.4%, alveolar in 9.8%, and undifferentiated in 9.8%. The majority of the patients were considered group III (47%) and group IV (25.5%) according the criteria of the Intergroup Rhabdomyosarcoma Study (IRS). Primary total tumour resection was performed in only 27.5% of the patients. The patients were treated with assigned regimens of IRS II and IRS III protocols. Radiotherapy was applied to 92.1% of the patients. Thirty-four patients (66.7%) were lost to follow up, and of the remaining 17 patients, 7 patients (41.2%) died, relapse occurred in 9 patients (52.9%) and 10 patients (58.8%) are alive. The percentage of cases lost to follow up during the first 10 years and the following 9 years of the study were 77.4% and 50%, respectively. In compliance with cancer treatment remains a major problem in developing countries.</p> |
| Keywords | rhabdomyosarcoma pediatric onocology chemotherapy |
| Amo Type | Article |
| Published Date | 2000-08 |
| Publication Title | Acta Medica Okayama |
| Volume | volume54 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 173 |
| End Page | 177 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 10985177 |
| Web of Sience KeyUT | 000089132800005 |
