JaLCDOI 10.18926/AMO/32277
FullText URL fulltext.pdf
Author Karakas, Zeynep| Agaoglu, Leyla| Biner, Betul| Devecioglu, Omer| Anak, Sema| Yalman, Nevin| Unuvar, Aysegul| Celik, Alaattin| Gedikoglu, Gunduz|
Abstract <p>Fifty-one children (median age: 4.5 years; 4 months-16 years) diagnosed with rhabdomyosarcoma were treated in our center between 1980-1999. The primary sites were head and neck in 31.4%, the genito-urinary system in 21.6%, and extremities in 9.8% of the patients. The histopathologic subtypes were embryonal in 80.4%, alveolar in 9.8%, and undifferentiated in 9.8%. The majority of the patients were considered group III (47%) and group IV (25.5%) according the criteria of the Intergroup Rhabdomyosarcoma Study (IRS). Primary total tumour resection was performed in only 27.5% of the patients. The patients were treated with assigned regimens of IRS II and IRS III protocols. Radiotherapy was applied to 92.1% of the patients. Thirty-four patients (66.7%) were lost to follow up, and of the remaining 17 patients, 7 patients (41.2%) died, relapse occurred in 9 patients (52.9%) and 10 patients (58.8%) are alive. The percentage of cases lost to follow up during the first 10 years and the following 9 years of the study were 77.4% and 50%, respectively. In compliance with cancer treatment remains a major problem in developing countries.</p>
Keywords rhabdomyosarcoma pediatric onocology chemotherapy
Amo Type Article
Published Date 2000-08
Publication Title Acta Medica Okayama
Volume volume54
Issue issue4
Publisher Okayama University Medical School
Start Page 173
End Page 177
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 10985177
Web of Science KeyUT 000089132800005