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ID 16307
Eprint ID
16307
FullText URL
Thumnail 95_459.pdf 788 KB
Title Alternative
Inhibitory effect of Ca(2+) antagonist on (45)Ca uptake by mast cells
Author
Tanizaki, Yoshiro
Komagoe, Haruki
Sudo, Michiyasu
Ohtani, Jun
Kitani, Hikaru
Matsuka, Yohko
Kimura, Ikuro
Akagi, Katsumi
Townley Robert G.
Abstract
(45)Ca uptake by rat peritoneal mast cells was observed, and the inhibitory effect of nifedipine, a Ca(2+) antagonist, on (45)Ca uptake by mast cells, stimulated by an antigen, comp. 48/80, concanavalin A and Ca ionophore A 23187, was examined. The increase in (45)Ca uptake by mast cells induced by the antigen paralleled the increase in mast cell number. A significant increase in the uptake of (45)Ca by mast cells was observed with the stimulation by the antigen, comp. 48/80, concanavalin A and Ca ionophore A 23187. The increased uptake of (45)Ca induced by antigen was inhibited by nifedipine, and this dose-dependent inhibitory effect of nifedipine on (45)Ca uptake was also observed in the mast cells stimulated by comp. 48/80, concanavalin A and Ca ionophore A 23187.
Keywords
肥満細胞
(45)Ca uptake
Ca(2+)拮抗剤
Published Date
1983-06-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume95
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
459
End Page
465
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/95/5-6/95_5-6_459/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma