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ID 13711
Eprint ID
13711
FullText URL
Thumnail 107_69.pdf 484 KB
Title Alternative
Effect of zonisamide on neurotransmitter release from hippocampal slice of E1 mice : A study of neurotransmitter release using an improved experimemtal system
Author
Endo, Atsushi
Abstract
Using an experimental apparatus for estimating neurotransmitter release from brain slices, which involved an improved type of perfusion chamber and more well-controlled tube lines than the previous one were aspartic acid and γ-aminobutyric acid (GABA) release from hippocampal slices from epileptic E1 mice estimated more exactly and stably. Zonisamide had no effect on the aspartic acid release from hippocampal slices of E1 mice by zonisamide. However, zonisamide accelerated dose dependently GABA release from hippocampal slices of non-stimulated E1 mice, though no such acceleration was observed in stimulated E1 mice, i. e., repeatedly convulsed E1 mice.
Keywords
E1マウス
アスパラギン酸
γ-アミノ酪酸
ゾニサミド
けいれん
Note
原著
Published Date
1995-08-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume107
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
69
End Page
78
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/107/7-8/107_7-8_69/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma