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ID 18406
Eprint ID
18406
FullText URL
Thumnail 74_629.pdf 371 KB
Title Alternative
Studies on Glutamic Decarboxylase in the Brain Ⅱ. Glutamic Decarboxyase Activity of Epileptogenic Cerebral Cortex
Author
Kondo, Osamu
Abstract
The activity of glutamic decarboxylase was measured with the use of cerebral cortices in human idiopathic epilpsy and in experimental epilespy of ep (epileptogenic) mice, of rabbits with local anaphylaxis of the brain and of vitamin B(6) deficiency mice and the folowing results were obtained. 1. While there can be recognized no significant defference in the activity of glutamic decarboxylase in non-focal cerebral cortex of human idiopathic epilepsy from that in the control (non-epileptic brain), the glutamic decarboxylase activity in the focal cortex of the human idiopathic epilepsy is markedly lower than that in the non-focal area. 2. The activity of glutamic decarboxylase in the cerebral cortex of adult ep mice is considerably decreased, but in the immature ep-mice that had not yet experienced convulsion its activity is rather accelerated. 3. The glutamic decarboxylase activity in the cerebral cortex of the rabbit with a local anaphylaxis is not significantly different from that in the normal control rabbit. 4. The activity of glutamic decarboxyase in the brain of vitamin B(6) deficient mice is markedly lower than that in the normal mice brain.
Published Date
1962-09-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume74
Issue
issue8-9
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
629
End Page
634
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/74/8-9/74_8-9_629/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma