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ID 16969
Eprint ID
16969
FullText URL
Thumnail 91_1035.pdf 9.89 MB
Title Alternative
Microvascular changes of gastric mucosa in the development of stress ulcer in rats A scanning electron microscopic study of vascular casts
Author
Chikasawa, Nobuyoshi
Abstract
Under a scanning electron microscope, the microcirculation in the stomachs of rats under stress was observed by a corrosion casting technique. Stress ulcers were induced by a cold immersion and restraint method. After a short time of stress, the vascular pattern showed serpentining and narrowing of the capillaries and a local depression of the capillary network. After a moderately long time, defects in the vascular network began to appear and outflowings of Mercox from the venule became prominant. Casts of interrupted collecting venules were frequently seen. With further increase in the time of stress, the interruptions in the cast of the capillaries and collecting venules which were dilated, increased. These vessel changes descended deeper and deeper into the mucosa vessels but were limited to the laminapropria and did not extend to the muscularis mucosae. After stress following truncal vagotomy, the vasculature showed serpenting and narrowing of the capillaries. But there were few defects in the capillaries and capillary network. In the case released from a short time of stress, Y-shaped duplicated vessels were often observed on the defective capillaries. In the case released from prolonged stress, newborn buds were seen on the defective capillaries and collecting vessels. Duplicated capillaries and collecting vessels ran toward the surface of the mucosa.
Keywords
ストレス潰瘍
メルコックス樹脂
毛細血管の蛇行
血行の途絶
樹脂の流出像
Published Date
1979-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume91
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1035
End Page
1064
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/91/7-8/91_7-8_1035/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma