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ID 15860
Eprint ID
15860
FullText URL
Thumnail 99_97.pdf 363 KB
Title Alternative
Quantitative analysis of carcinoma-associated glycoproteins which bind PNA lectin.
Author
Suwa, Fumiaki
Abstract
Glycoproteins (PNABGP : PNA binding glycoproteins)possessing inhibitory activity against hemagglutination of PNA, a lectin specific for Galβ(1→3)Gal NAc linkage in the non-reducing end of carbohydrate chains, were detected in the serum of patients with malignant tumors. These glycoproteins were purified from ascites collected from patients bearing carcinoma of the liver, pancreas and stomach by affinity chromatography using PNA, anti-whole human serum and anti-cirrhotic ascitic fluid. SDS-polyacrylamide gel electrophoresis of these glycoproteins yielded are main band (120K daltons). Using this preparation, PNABGP in the serum was quantitated by an enzyme-linked immunosorbent assay (ELISA). The levels of these glycoproteins were high in hepatocellular carcinoma and other malignancies.
Keywords
PNAレクチン
ELISA
赤血球凝集阻止試験
腹水
悪性腫瘍
Published Date
1987-02-28
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume99
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
97
End Page
104
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/99/1-2/99_1-2_97/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma