start-ver=1.4
cd-journal=joma
no-vol=99
cd-vols=
no-issue=1-2
article-no=
start-page=97
end-page=104
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1987
dt-pub=19870228
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Quantitative analysis of carcinoma-associated glycoproteins which bind PNA lectin.
kn-title=悪性腫瘍関連物質としてのPNAレクチン結合性糖蛋白について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Glycoproteins (PNABGP : PNA binding glycoproteins)possessing inhibitory activity against hemagglutination of PNA, a lectin specific for Galβ(1→3)Gal NAc linkage in the non-reducing end of carbohydrate chains, were detected in the serum of patients with malignant tumors. These glycoproteins were purified from ascites collected from patients bearing carcinoma of the liver, pancreas and stomach by affinity chromatography using PNA, anti-whole human serum and anti-cirrhotic ascitic fluid. SDS-polyacrylamide gel electrophoresis of these glycoproteins yielded are main band (120K daltons). Using this preparation, PNABGP in the serum was quantitated by an enzyme-linked immunosorbent assay (ELISA). The levels of these glycoproteins were high in hepatocellular carcinoma and other malignancies.
en-copyright=
kn-copyright=

en-aut-name=SuwaFumiaki
en-aut-sei=Suwa
en-aut-mei=Fumiaki
kn-aut-name=諏訪文明
kn-aut-sei=諏訪
kn-aut-mei=文明
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学医学部第一内科学教室
en-keyword=PNAレクチン
kn-keyword=PNAレクチン
en-keyword=ELISA
kn-keyword=ELISA
en-keyword=赤血球凝集阻止試験
kn-keyword=赤血球凝集阻止試験
en-keyword=腹水
kn-keyword=腹水
en-keyword=悪性腫瘍
kn-keyword=悪性腫瘍
END