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ID 16257
Eprint ID
16257
FullText URL
Thumnail 96_305.pdf 422 KB
Title Alternative
Clinical studies on sporadic hepatitis A: features, course and prognosis
Author
Fukuda, Tetsuya
Yamada, Gotaro
Ogawa, Hiromichi
Okushin, Hiroaki
Hyodo, Ichinosuke
Nishihara, Takashi
Mizuno, Motowo
Sakamoto, Yuji
Nagashima, Hideo
Kobayashi, Toshinari
Yoshida, Tomoro
Abstract
Clinical and laboratory features of 66 patients with sporadic hepatitis A were evaluated from October 1978 to July 1981. Jaundice was reported in 88.6% of the patients, and the frequency of skin rash was 15.7%. Less than 5% atypical lymphocytes were noted in 29.5% of the patients. Proteinuria and hematuria were present in 23.4% and 6.3% of the patients. However, immune complexes were not detected in their sera. One of the patients who had hematuria developed acute renal failure. About 10% of the patients transiently showed both low levels of cholinesterase and cholesterol and prolongation of the prothrombin time. There was no patient with fulminant hepatic failure. Liver function tests returned to normal except for 3 patients within 3 months. For 10 months after the onset, slight elevation of SGPT peristed in the patient with acute renal failure and also in a patients with a previous history of liver disease. One of two patients with acute intrahepatic cholestasis showed protraction of mild hyperbilirubinemia more than 6 months after the onset of acute illness.
Keywords
散発性A型肝炎
免疫複合体
重症化
遷延化
Published Date
1984-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume96
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
305
End Page
312
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/96/3-4/96_3-4_305/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma