Title Alternative Alzheimer’s disease : Relationship between the Alzheimer’s disease and human microbiome
FullText URL srfa_107_005_010.pdf
Author Fujii, Yusuke| Morita, Hidetoshi|
Abstract Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by memory and language disorder. The accumulation of senile plaques called β-amyloid and neurofibrillary tangles involving protein tau in the brains of AD patients have been considered as two hallmarks of AD. In AD, it is reported that accumulation of β-amyloid may be observed 25 years before onset, supporting early diagnosis and treatment by brain image analysis, because several techniques have recently been developed to detect β-amyloid and tau protein in brains of persons diagnosed with AD. AD patients are usually suffering from other diseases such as diabetes or periodontal disease, and there is accumulating data to show that these diseases associate with the human microbiome, such as gut and oral microbiota. In this report, the relation ship between AD and the human microbiome is reviewed.
Publication Title Scientific Reports of the Faculty of Agriculture, Okayama University
Published Date 2018-02-01
Volume volume107
Start Page 5
End Page 10
ISSN 2186-7755
language 日本語
File Version publisher