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ID 14185
Eprint ID
14185
FullText URL
Thumnail 106_655.pdf 330 KB
Title Alternative
Maintenance therapy with erythropoietin for renal anemia
Author
Nagake, Yoshio
Makino, Hirofumi
Haramoto, Toshinori
Matsumoto, Mitsuhito
Hiramatsu, Makoto
Mino, Yasuaki
Nishimura, Shigeaki
Taniai, Kazuhi
Kumagai, Isao
Komoto, Kiichi
Takehisa, Yoshiaki
Matsuura, Umeharu
Suga, Yoshihiko
Ota, Zensuke
Abstract
The beneficial effect of recombinant human erythropoietin (EPO) for renal anemia in patients with chronic hemodialysis has been esthablishel. EPO is reported to be effective against renal anemia when adeministered at a dose 3,000 units three times a week. However, only a few studies have been made on the therapy to maintain the anemia-improving effect of EPO. In the present study, we performed EPO maintenance therapy on 22 hemodialysis patients with renal anemia. EPO was initialy administered at a dose of 3,000 units three times a week, and maintenance therapy was initiated after 12 weeks of treatment. The patients were divided into two groups, with EPO being administered at a dose of 1,500 units twice a week to one group and three times a week to the other. The duration of maintenance therapy was set at eight weeks. The anemia-improving effect of EPO was found to be satisfactorily maintained in both groups and no significant difference was noted between them. According, it may be better to use the lower dose regimen of 1,500 units twice a week for the maintenance therapy of renal anemia.
Keywords
腎性貧血
エリスロポエチン
維持投与法
Note
原著
Published Date
1994
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume106
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
655
End Page
661
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/106/5-6/106_5-6_655/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma