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ID 17169
Eprint ID
17169
FullText URL
Thumnail 89_859.pdf 255 KB
Title Alternative
Studies on the lipid of rat dental pulp II. Lipid peroxidation of rat incisor pulp
Author
Hashimoto, Gonosuke
Abstract
1) ラット切歯歯髄のホモゲネートにおいてFe(++)誘導脂質過酸化反応活性が認められた.エックス線全身照射(1000R)したラットより分離した歯髄ホモゲネートのFe(++)誘導脂質過酸化反応は非照射のそれに比して促進がみられた. 2) ラット切歯歯髄脂質の構成脂質中で,過酸化反応を誘起し易い脂質はリン脂質で,中性脂質ではほとんど誘起されなかった. 3) リン脂質中,そのリン脂質構成の大部分をしめるボスファチジルコリン,ホスファチジルエタノールアミン,ホスファチジルセリンにおいて過酸化反応が誘起し得た.中でもホスファチジルエタノールアミンの脂質重量当りの比活性が最も高い値を示した. 4) リン脂質の脂肪酸組成では,アラキドン酸をはじめ,不飽和含量が多く,トリグリセリドではアラキドン酸はみられなかった.
Abstract Alternative
Lipid peroxidation of dental pulp homogenate isolated from rat incisors was induced by ferrous ion. Lipd peroxidation of dental pulp homogenate isolated from rat 3 days after wholebody irradiation at 1000R x-ray was also induced by ferrous ion, and the activity was higher than that of control homogenate. In the extracted lipid components of dental pulps, the peroxidation of phospholipid were marked, but those of choresterol, choresterol ester, mono-,di-, tri-glycerides, and fatty acid (non-esterified) were slightly or negligible. In the phospholipid components, the peroxidation was highly observed in lecithin, phosphatidyl ethanolamine and phosphatidyl serine, and the peroxidation of phosphatidyl ethanolamine showed the most value in them. By the analysis of the fatty acid composition, arachidonic acid was included in the phos-pholipid but not in the triglyceride, suggesting arachidonic acid is substrate of the peroxidation of dental pulps.
Published Date
1977-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume89
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
859
End Page
863
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/89/7-8/89_7-8_859/_article/-char/ja/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma