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ID 15865
Eprint ID
15865
FullText URL
Thumnail 100_119.pdf 12.2 MB
Title Alternative
Light and electron microscopic studies of postnatal developmentof the rat amygdala by Timm's sulphide silver method
Author
Tseng, I-Ming
Abstract
The distribution of zinc and postnatal development of the rat amygdala were investigated by light and electron microscopy with Timm's sulphide silver method.By Timm's reaction and toluidine blue staining, the rat amygdala could be divided into cortical(CO), lateral(L), basolateral(ABL), basomedial(ABM), central(C), medial(M) and intercated(I) nuclear regions. CO was the most strongly positive to Timm's reaction, L, ABM and C were strongly positive, ABL was also positive, and I and M were weakly positive. In newborns, no positive Timm's reaction could be observed, but a very weakly positive reaction was observed from the 5th postnatal day. The reaction became stronger with development, and reached the strength of that of the adult on the 30th postnatal day.Electron microscopically, the deposits of silver grains were only located in the nerve fiber endings containing many small clear vesicles. This finding is quite similar to that described in the mossy fiber endings in the hippocampal formation. Deposits of silver grains could not be found in newborns, and only very few could be observed after the 5th postnatal day. The number of deposits increased with age, and reached that of the adult from the 20th to the 30th postnatal days.It was elucidated that a significant increase in the number of silver grains per square 10(-8) centimeter of Timm's positive nerve fiber endings occurred between the 10th and 20th postnatal days.These findings suggest that zinc exists in the nerve fiber endings in the rat amygdala and the amount of zinc increases with age. Zinc may play an important role in synaptic transmission.
Keywords
扁桃体
基底外側核
Timm硫化銀法
電子顕微鏡
Published Date
1988
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume100
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
119
End Page
133
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/100/1-2/100_1-2_119/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma