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ID 19541
Eprint ID
19541
FullText URL
Thumnail 71_2555.pdf 3.75 MB
Title Alternative
Studies on Serum Polysaccharides in Patients with Gastric Cancer and in Rabbits Bearing Brown-Pearce Tumor Part 1. Studies on Serum Polysaccharides in Patients with Gastric Cancer
Author
Tago, Kengo
Abstract
The author, by the method of Weimer and Moshin, has determined the total serum polysaccharides (TSP) and the serum mucoprotein polysaccharide (SMP) in patients with gastric cancer, gastric ulcer, and in healthy persons. At the same time, sera in these persons were analized by the apparatus for paper electrophoresis, and stained with Amidoschwarz 10 B for serum protein, with the periodic acid Schiff's reaction (PAS) and the double oxidation toluidine blue reaction (DOT) for serum polysaccharides. The results obtained in patients with gastric cancer were as follows; 1) The TSP, SMP and those ratios to the serum protein were significantly elevated. Those levels were increased in parallel with size and metastatic spread of the tumor. 2) In the serum protein fractions, the decrease in albumin and increase in α(1),α(2) globulin were found. These changes were almost parallel to the growth and spread of the gastric cancer. No significant changes were recognized in β, γ globulins, but the latter increased at the late stage of the gastric cancer. 3) In the tests by the PAS reaction, the fall of albumin and elevation of α(1), α(2) globulin fractions were noticed. On the contrary, there were decrases in β, γ globulin. The elevations of α(1), α(2) globulin fractions were almost parallel to the growth and spread of the gastric cancer. 4) In the tests by the DOT α(1), α(2) globulin fractions were also noticed. There was an intimate relationship between the growth, spread of the gastric cancer and the fluctuation of α(1) globulin fraction. No gsinificant changes were recognized in the other fractions. 5) In patients with gastric cancer, the TSP, SMP, these ratios to the serum protein, and α(2) globulin fraction (DOT) were significantly increased more than those in patients with gastric ulcer. It would be said that the gastric cancer and the peptic ulcer were well differentiated in accordance with the level of SMP or the ratio to serum protein than the others.
Published Date
1959-04-25
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue5-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2555
End Page
2566
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/5-2/71_5-2_2555/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma