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ID 49381
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Title Alternative
Mesalazine suppositories and their clinical application
Author
Funagakure, Keiko
Horita, Syuzi
Hamaoka, Terutaka
Tasaka, Takeshi
Tatibana, Hiroshi
Murakami, Takako
Toyokawa, Tatuya
Sato, Eiji
Tomoda, Jun
Abstract
Ulcerative proctitis (UP) is a prevalent condition associated with increased morbidity, and topical mesalazine (5-aminosalicylic acid [5-ASA]) is known to inhibit the inflammatory processes in UP. We successfully devised mesalazine suppositories, in which 250mg mesalazine was equally distributed and remained stable for at least 2 weeks. We evaluated the effect of using mesalazine suppositories twice a day (BID) on two UP patients. The results demonstrated that mesalazine suppositories were efficacious, well tolerated and safe for the long-term maintenance of UP remission.
Keywords
メサラジン坐薬(mesalazine suppositories)
潰瘍性大腸炎直腸型(ulcerative proctitis)
Note
原著(Original Paper)
Published Date
2013-04-01
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume125
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
29
End Page
33
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
Copyright (c) 2013 岡山医学会
File Version
publisher
Refereed
True
DOI
Eprints Journal Name
joma