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ID 16186
Eprint ID
16186
FullText URL
Thumnail 97_607.pdf 1.82 MB
Title Alternative
Clinical studies on a new method of chromo-endoscopy with brilliant blue in the diagnosis of gastric cancer lesionsPart 2. Basic studies on the chromo-endoscopic findings of the surface of the gastric mucosa
Author
Yorimitsu, Yukio
Abstract
This report is concerned with basic studies on chromo-endoscopic findings using Brilliant Blue (BB), with special reference to the affinity of BB dye with mucus and fibrin and also to the dissecting microscopic surface structure of the normal and cancerous gastric mucosa. The BB solution stained mucus and fibrin on the mucosal surface of the stomach at pHs ranging from 1 to 4. Stained mucus appeared translucent, and stained fibrin opaque. The mucus or fibrin clot bound with BB appeared blue at any pH of the dyebath, even with a green BB solution at pH 1. A thin layer of mucus was stained with BB and destained with a 1.0% sodium bicarbonate solution in a few seconds at 37℃, while a small piece of fibrin clot was stained and destained much more slowly (in approximately 30 minutes) under the same conditions. The normal mucosa (including fundic mucosa, pyloric mucosa, and that with glandular atrophy and intestinal metaplasia) was covered with a thin layer of viscous mucus. The chromo-endoscopic appearance depended mostly on the stain characteristics of BB and the fine properties of the mucosal surface of the stomach. The "well-demarcated redness" characteristic of a gastric cancer lesion mainly of the depressed type proved to reflect an unstained or less-stained mucosal territory associated with such factors as lack of the normal-appearing layer of viscous mucus over the cancerous surface, easy loss of the insoluble mucus- and fibrin-like substances attached to the cancerous surface, and compactness of the surface structure in the case of well-differentiated tubular adenocarcinomas.
Keywords
胃癌
色素内視鏡検査
ブリリアントブルー
フィブリン
Published Date
1985-08-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume97
Issue
issue7-8
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
607
End Page
621
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/97/7-8/97_7-8_607/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma