Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

<Availability>
Some items are not available because of decision by its author or publisher.

Clinical significance of airway inflammation in bronchcial asthma. Comparison with chronic obstructive bronchiolitis.

Tanizaki, Yoshiro
Kitani, Hikaru
Mifune, Takashi
Kajimoto, Kazuhiro
Sugimoto, Keisuke
Yokota, Satoshi
Hiramatsu, Junichi
Kawaraya, Masashi
Ochi, Koji
Harada, Hideo
Tada, Shinya
Kimura, Ikuro
Abstract
Clinical significanoce of airway inflammation was assessed in 28 patients with bronchial asthma, and the results were compared with those in 9 patients with chronic obstructive bronchiolitis (COB). 1. Total cell number in bronchoalveolar lavage(BAL) fluid was markedly increased in patients with COB (51.0×10(6)), which was significantly greater than that in those with bronchial asthma (9.6×10(6) ). 2. The proportion of BAL macrophages was significantly higher in patients with bronchial asthma than in those with COB. However, the, absolute number of BAL macrophages was not significantly different between them. 3. The proportion of BAL lymphocytes was higher in patients with bronchial asthma than in those with COB, but this difference was not signifcant. In contrast, the absolute number of BAL lymphocytes was significantly greater in patients with COB than in those with bronchial asthma. 4. The proportion and the number of BAL neutrophils were markedly increased in patients with COB compared to those with bronchial asthma. 5. The proportion and the number of BAL eosinophils were higher in patients with bronchial asthma than in those with COB, although these defferences were not significant. The results suggest that airway inflammation in bronchial asthma is not so intensive as that in COB.
Keywords
airway inflammation (気道炎症反応)
bronchial asthma (気管支喘息)
chronic obstructive bronchiolitis (慢性閉塞性細気管支炎)
lymphocytes (リンパ球)
neutrophils (好中球)
ISSN
0918-7839
NCID
AN10430852